scholarly journals A randomized controlled trial to assess the effectiveness and safety of acupuncture for overactive bladder: a study in Hong Kong population

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Zhi-xiu Lin ◽  
Ngai Ho Tony Chan ◽  
Yiu-keung Kwan ◽  
Yu Tat Chan ◽  
Hongwei Zhang ◽  
...  
Keyword(s):  
Urinary Incontinence ◽  
Hong Kong ◽  
Overactive Bladder ◽  
Acupuncture Treatment ◽  
Sham Acupuncture ◽  
Urgency Urinary Incontinence ◽  
Urinary Frequency ◽  
Night Time ◽  
Acupuncture Intervention

Abstract Background Around 15% of the Hong Kong population was found to suffer from overactive bladder (OAB), but the current available treatments, such as medication, behavioral therapy and physical therapy are unsatisfactory. Previous studies have suggested that acupuncture may have promising effect for OAB, but some limitations on the study design render the evidence questionable. This study aimed to evaluate the effectiveness and safety of acupuncture treatment for patients with OAB in Hong Kong. Methods One hundred patients with OAB were enrolled. The patients were randomized to receive either active acupuncture or sham needle intervention twice a week for 8 consecutive weeks, and had a follow-up consultation 12 weeks after the completion of acupuncture intervention. The primary outcome assessment was the 3-Day Voiding Diary, which records daytime and night-time urinary frequency and symptoms, at the baseline, the end of the 8-week intervention and 12 weeks after acupuncture intervention. Secondary outcomes included Urine NGF level, Incontinence Impact Questionnaire (IIQ-7) and Urogenital Distress Inventory (UDI-6), as well as Overactive Bladder Symptom Score (OABSS). Results After 16 sessions of treatment, when compared with the baseline, both active and sham acupuncture significantly reduced the frequency of urgency urinary incontinence (UUI), daytime and night-time urinary frequency as well as the scores of IIQ-7, UDI-6 and OABSS. Moreover, the treatment effects could last for at least 3 months. However, no significant difference in frequency of UUI and daytime urinary frequency was found between the active and sham acupuncture groups. On the other hand, the night-time urinary frequency decreased more significantly during the treatment and follow-up in the active acupuncture group than in the sham control group after controlling baseline night-time urinary frequency. Urine NGF level could not be detected by ELISA method in our experiments. Conclusion This study suggests a beneficial effect of acupuncture on improving OAB symptoms. Both active and sham acupuncture treatment were able to improve the symptoms of frequency of urgency urinary incontinence, and the daytime and night-time urinary frequency, while only mild adverse effects were found. This project was unable to establish the specific effect of acupuncture for OAB. Trial registration Chinese Clinical Trial Registry, ChiCTR-INR-16010048. Registered on 29 Nov 2016.

Urinary Incontinence and Overactive Bladder Syndrome

2018 ◽  
Author(s):  
Kristie A. Greene ◽  
Lennox Hoyte
Keyword(s):  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Stress Incontinence ◽  
Urge Incontinence ◽  
Valsalva Maneuver ◽  
Abdominal Pressure ◽  
Sudden Increase ◽  
Overactive Bladder Syndrome ◽  
Urinary Frequency ◽  
Mixed Incontinence

Urinary incontinence falls into two broad categories: stress incontinence and urge incontinence. Stress urinary incontinence occurs when urethral closure pressure cannot increase sufficiently to compensate for a sudden increase in intra-abdominal pressure, as from a cough or Valsalva maneuver. Urge urinary incontinence occurs when an unintended bladder contraction creates an insuppressible urge to void, leading to urinary leakage. When women have signs and/or symptoms of both stress and urge incontinence, it is referred to as mixed urinary incontinence. Overactive bladder syndrome is defined by the Standardization Subcommittee of the International Continence Society (ICS) as urinary urgency, with or without urge incontinence and usually with frequency and nocturia. Nocturia, which is often associated with urinary frequency, is defined as a need to urinate that awakens the person during the night. This chapter discusses the epidemiology and physiology of urinary incontinence and overactive bladder syndrome in women, as well as diagnosis and treatment. Tables list foods and beverages that may cause urinary frequency and urgency; features of urge incontinence, stress incontinence, and mixed incontinence; American Urologic Association (AUA) guidelines regarding level of evidence and indications for adult urodynamics; and currently available antimuscarinic drugs and their dosages, selectivity, efficacy, and side effects. Figures depict the journal of someone with mixed incontinence, a typical urodynamics suite, a urodynamic study of someone with detrusor overactivity, incontinence pessaries, and transobturator and retropubic slings. This review contains 5 figures, 5 tables, and 44 references.

Urinary Incontinence and Overactive Bladder Syndrome

2017 ◽  
Author(s):  
Kristie A. Greene ◽  
Lennox Hoyte
Keyword(s):  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Stress Incontinence ◽  
Urge Incontinence ◽  
Valsalva Maneuver ◽  
Abdominal Pressure ◽  
Sudden Increase ◽  
Overactive Bladder Syndrome ◽  
Urinary Frequency ◽  
Mixed Incontinence

Urinary incontinence falls into two broad categories: stress incontinence and urge incontinence. Stress urinary incontinence occurs when urethral closure pressure cannot increase sufficiently to compensate for a sudden increase in intra-abdominal pressure, as from a cough or Valsalva maneuver. Urge urinary incontinence occurs when an unintended bladder contraction creates an insuppressible urge to void, leading to urinary leakage. When women have signs and/or symptoms of both stress and urge incontinence, it is referred to as mixed urinary incontinence. Overactive bladder syndrome is defined by the Standardization Subcommittee of the International Continence Society (ICS) as urinary urgency, with or without urge incontinence and usually with frequency and nocturia. Nocturia, which is often associated with urinary frequency, is defined as a need to urinate that awakens the person during the night. This chapter discusses the epidemiology and physiology of urinary incontinence and overactive bladder syndrome in women, as well as diagnosis and treatment. Tables list foods and beverages that may cause urinary frequency and urgency; features of urge incontinence, stress incontinence, and mixed incontinence; American Urologic Association (AUA) guidelines regarding level of evidence and indications for adult urodynamics; and currently available antimuscarinic drugs and their dosages, selectivity, efficacy, and side effects. Figures depict the journal of someone with mixed incontinence, a typical urodynamics suite, a urodynamic study of someone with detrusor overactivity, incontinence pessaries, and transobturator and retropubic slings. This review contains 5 figures, 5 tables, and 44 references.

Overactive bladder and urgency urinary incontinence in men undergoing artificial urinary sphincter placement

2020 ◽  
Vol 39 (5) ◽  
pp. 1489-1493
Author(s):  
Mona S. Jahromi ◽  
Kyrra Engle ◽  
Daniel Furlong ◽  
Alejandra Guevara Méndez ◽  
Christopher S. Gomez
Keyword(s):  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Artificial Urinary Sphincter ◽  
Urgency Urinary Incontinence ◽  
Urinary Sphincter

scholarly journals Acupuncture Improving Early Sexual Development of Girls with Peripheral Precocious Puberty: A Prospective Cohort Study

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Lili Liu ◽  
Naijun Wan ◽  
Huihui Sun
Keyword(s):  
Precocious Puberty ◽  
Hormone Level ◽  
Acupuncture Treatment ◽  
Tanner Stage ◽  
Sex Hormone ◽  
Serious Adverse Events ◽  
Acupuncture Intervention ◽  
Symptom Scores ◽  
Peripheral Precocious Puberty

Objective. To study primarily on the effect of acupuncture on breast Tanner stage, serum sex hormone level, and TCM symptom scores in girls with peripheral precocious puberty (PPP). Methods. 19 eligible patients diagnosed with PPP received acupuncture intervention for 12 weeks, twice a week for 12 weeks, 24 sessions of acupuncture treatment in all, and then follow-up for 12 weeks. The primary outcome was the change in serum luteinizing hormone (LH) level, follicle-stimulating hormone (FSH) level, and breast Tanner stage at 12-week treatment and 12-week follow-up. Serum estradiol (E2) level and TCM symptom scores were also assessed. Results. Nineteen patients with peripheral precocious puberty were treated with acupuncture. After the 12-week acupuncture intervention, the serum LH level, breast Tanner stage, and TCM symptom scores decreased significantly compared with baseline (P<0.05); the serum FSH and E2 level did not change significantly after the 12-week treatment (P>0.05). After the 12-week follow-up, breast Tanner stage and TCM symptom scores decreased significantly compared with baseline (P<0.05), and there was no statistical difference between serum sex hormone (LH, FSH, and E2) level and baseline level (P>0.05). During the period of acupuncture treatment, no side effects or serious adverse events occurred. Conclusions. Acupuncture is effective in regulating the hormone level and controlling early development process. It may be a viable alternative to the treatment of peripheral precocious puberty in girls. However, further randomized controlled trials are needed.

Urinary Incontinence and Overactive Bladder Syndrome

2018 ◽  
Author(s):  
Kristie A. Greene ◽  
Lennox Hoyte
Keyword(s):  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Stress Incontinence ◽  
Urge Incontinence ◽  
Valsalva Maneuver ◽  
Abdominal Pressure ◽  
Sudden Increase ◽  
Overactive Bladder Syndrome ◽  
Urinary Frequency ◽  
Mixed Incontinence

Urinary incontinence falls into two broad categories: stress incontinence and urge incontinence. Stress urinary incontinence occurs when urethral closure pressure cannot increase sufficiently to compensate for a sudden increase in intra-abdominal pressure, as from a cough or Valsalva maneuver. Urge urinary incontinence occurs when an unintended bladder contraction creates an insuppressible urge to void, leading to urinary leakage. When women have signs and/or symptoms of both stress and urge incontinence, it is referred to as mixed urinary incontinence. Overactive bladder syndrome is defined by the Standardization Subcommittee of the International Continence Society (ICS) as urinary urgency, with or without urge incontinence and usually with frequency and nocturia. Nocturia, which is often associated with urinary frequency, is defined as a need to urinate that awakens the person during the night. This chapter discusses the epidemiology and physiology of urinary incontinence and overactive bladder syndrome in women, as well as diagnosis and treatment. Tables list foods and beverages that may cause urinary frequency and urgency; features of urge incontinence, stress incontinence, and mixed incontinence; American Urologic Association (AUA) guidelines regarding level of evidence and indications for adult urodynamics; and currently available antimuscarinic drugs and their dosages, selectivity, efficacy, and side effects. Figures depict the journal of someone with mixed incontinence, a typical urodynamics suite, a urodynamic study of someone with detrusor overactivity, incontinence pessaries, and transobturator and retropubic slings. This review contains 5 figures, 5 tables, and 44 references.

Sign in / Sign up

Export Citation Format

Share Document