Whole brain radiation therapy alone versus radiosurgery for patients with 1–10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial

Denise Bernhardt; Adriane Hommertgen; Daniela Schmitt; Rami El Shafie; Angela Paul; Laila König; Johanna Mair-Walther; Johannes Krisam; Christina Klose; Thomas Welzel; Juliane Hörner-Rieber; Jutta Kappes; Michael Thomas; Claus Peter Heußel; Martin Steins; Meinhard Kieser; Jürgen Debus; Stefan Rieken

doi:10.1186/s13063-018-2745-x

Whole brain radiation therapy alone versus radiosurgery for patients with 1–10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial

Trials ◽

10.1186/s13063-018-2745-x ◽

2018 ◽

Vol 19 (1) ◽

Cited By ~ 6

Author(s):

Denise Bernhardt ◽

Adriane Hommertgen ◽

Daniela Schmitt ◽

Rami El Shafie ◽

Angela Paul ◽

...

Keyword(s):

Lung Cancer ◽

Randomized Controlled Trial ◽

Radiation Therapy ◽

Brain Metastases ◽

Controlled Trial ◽

Small Cell ◽

Small Cell Lung ◽

Randomized Controlled ◽

Whole Brain Radiation ◽

Brain Radiation

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1386P Anlotinib combined with whole brain radiation therapy (WBRT) for advanced non-small cell lung cancer with multiple brain metastases: An open-label, single-arm phase II trial

Annals of Oncology ◽

10.1016/j.annonc.2020.08.1700 ◽

2020 ◽

Vol 31 ◽

pp. S881

Author(s):

X. Zhu ◽

H. Tao ◽

C. Kong ◽

X. Song ◽

N. Zhang ◽

...

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Phase Ii Trial ◽

Small Cell ◽

Small Cell Lung ◽

Open Label ◽

Whole Brain Radiation ◽

Brain Radiation

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Comparison of Whole Brain Radiation Therapy and Locally Limited Radiation Therapy in the Treatment of Solitary Brain Metastases from Non-small Cell Lung Cancer

Neurologia medico-chirurgica ◽

10.2176/nmc.36.364 ◽

1996 ◽

Vol 36 (6) ◽

pp. 364-369 ◽

Cited By ~ 19

Author(s):

Keisuke UEKI ◽

Masao MATSUTANI ◽

Osamu NAKAMURA ◽

Yoshiaki TANAKA

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

Whole Brain Radiation ◽

Brain Radiation ◽

Solitary Brain Metastases

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Faculty Opinions recommendation of Phase II trial of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non-small-cell lung cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717976512.793472688 ◽

2013 ◽

Author(s):

Marc Chamberlain

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Phase Ii ◽

Phase Ii Trial ◽

Small Cell ◽

Small Cell Lung ◽

Whole Brain Radiation ◽

Brain Radiation

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Toward the clarification of the role of whole-brain radiation therapy for brain metastases from non-small cell lung cancer: a comment about the QUARTZ trial

Translational Cancer Research ◽

10.21037/tcr.2016.12.71 ◽

2016 ◽

Vol 5 (S7) ◽

pp. S1465-S1468

Author(s):

Hirotake Saito ◽

Toshimichi Nakano ◽

Miki Shioi ◽

Hidefumi Aoyama

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

Whole Brain Radiation ◽

Brain Radiation

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Veliparib in combination with whole-brain radiation therapy for patients with brain metastases from non-small cell lung cancer: results of a randomized, global, placebo-controlled study

Journal of Neuro-Oncology ◽

10.1007/s11060-016-2275-x ◽

2016 ◽

Vol 131 (1) ◽

pp. 105-115 ◽

Cited By ~ 25

Author(s):

Pierre Chabot ◽

Te-Chun Hsia ◽

Jeong-Seon Ryu ◽

Vera Gorbunova ◽

Cristobal Belda-Iniesta ◽

...

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Controlled Study ◽

Small Cell Lung ◽

Whole Brain Radiation ◽

Brain Radiation

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Phase II Study of Erlotinib with Concurrent Whole-brain Radiation Therapy for Patients with Brain Metastases from Non-small Cell Lung Cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2011.06.280 ◽

2011 ◽

Vol 81 (2) ◽

pp. S136 ◽

Cited By ~ 2

Author(s):

J.W. Welsh ◽

E. Kim ◽

A. Amini ◽

P. Allen ◽

J. Chang ◽

...

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Small Cell ◽

Small Cell Lung ◽

Whole Brain Radiation ◽

Brain Radiation

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Comparative effectiveness of stereotactic radiosurgery versus whole-brain radiation therapy for patients with brain metastases from breast or non-small cell lung cancer

Cancer ◽

10.1002/cncr.30188 ◽

2016 ◽

Vol 122 (20) ◽

pp. 3243-3244

Author(s):

Jacob A. Miller ◽

Rupesh Kotecha ◽

John H. Suh

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Stereotactic Radiosurgery ◽

Comparative Effectiveness ◽

Small Cell ◽

Small Cell Lung ◽

Whole Brain Radiation ◽

Brain Radiation

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A Phase 3 Trial of Whole Brain Radiation Therapy and Stereotactic Radiosurgery Alone Versus WBRT and SRS With Temozolomide or Erlotinib for Non-Small Cell Lung Cancer and 1 to 3 Brain Metastases: Radiation Therapy Oncology Group 0320

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2012.11.042 ◽

2013 ◽

Vol 85 (5) ◽

pp. 1312-1318 ◽

Cited By ~ 183

Author(s):

Paul W. Sperduto ◽

Meihua Wang ◽

H. Ian Robins ◽

Michael C. Schell ◽

Maria Werner-Wasik ◽

...

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Radiation Therapy Oncology Group ◽

Small Cell ◽

Oncology Group ◽

Small Cell Lung ◽

Phase 3 ◽

Whole Brain Radiation ◽

Brain Radiation

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PD5-2-8: Predictors of survival for non-small-cell lung cancer patients with brain metastases treated with whole brain radiation therapy: pooled data from two randomized trials

Journal of Thoracic Oncology ◽

10.1097/01.jto.0000283434.35380.3b ◽

2007 ◽

Vol 2 (8) ◽

pp. S478

Author(s):

Markus F. Renschler ◽

Jennifer A. Smith ◽

See-Chun Phan ◽

John Suh ◽

Minesh P. Mehta

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Randomized Trials ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Pooled Data ◽

Whole Brain Radiation ◽

Brain Radiation

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Delayed leukoencephalopathy of non-small cell lung cancer patients with brain metastases underwent whole brain radiation therapy

Journal of Neuro-Oncology ◽

10.1007/s11060-015-1888-9 ◽

2015 ◽

Vol 125 (1) ◽

pp. 177-181 ◽

Cited By ~ 5

Author(s):

Xiaoling Zhong ◽

Biao Huang ◽

Jieying Feng ◽

Wanqun Yang ◽

Hongjun Liu

Keyword(s):

Lung Cancer ◽

Radiation Therapy ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Whole Brain Radiation ◽

Brain Radiation

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