scholarly journals Successful medical management of acute mesenteric ischemia due to superior mesenteric and portal vein thrombosis in a 27-year-old man with protein S deficiency: a case report

2017 ◽  
Vol 11 (1) ◽  
Author(s):  
N. P. Osti ◽  
D. N. Sah ◽  
R. S. Bhandari
Keyword(s):  
Case Report ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Medical Management ◽  
Mesenteric Ischemia ◽  
Acute Mesenteric Ischemia ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

PROTEIN S DEFICIENCY WITH PORTAL VEIN THROMBOSIS : A CASE REPORT

2014 ◽  
Vol 1 (11) ◽  
pp. 1383-1386
Author(s):  
Kekathi Vidyasagar ◽  
Saifullah Quraishi S M ◽  
Ravi Theja ◽  
Chandrashekar S
Keyword(s):  
Case Report ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

scholarly journals A Rare Case of Portal Vein Thrombosis due to Protein S deficiency in a patient with Decompensated Cryptogenic CLD with Portal Hypertension, Completely Recanalized by Single Oral Anticoagulant-Rivaroxaban

2020 ◽  
pp. 29-37
Author(s):  
Richmond Ronald Gomes
Keyword(s):  
Portal Hypertension ◽  
Liver Disease ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Oral Anticoagulant ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency ◽  
Hepatic Portal

Venous thromboembolic diseases are a group of heterogeneous diseases with different clinical forms and prognosis. Abdominal venous thrombosis may present either as Budd-Chiari syndrome (BCS) caused by hepatic vein or proximal inferior vena cava (IVC) obstruction or as an extra hepatic portal obstruction (EHPVO) caused by Portal vein thrombosis or mesenteric vein thrombosis. Portal vein thrombosis (PVT) is a rare form of venous thrombosis that affects the hepatic portal vein flow, which can lead to portal hypertension. Treatment of PVT includes anticoagulants, thrombolysis, and insertion of shunts, bypass surgery, and liver transplantation. Single anticoagulation therapy can be associated with a reduction in new thrombotic episodes. Here we experienced a 23 year old young lady with history of recent intrauterine death (IUD) diagnosed as PVT provoked by protein S deficiency with newly diagnosed decompensated cryptogenic chronic liver disease with portal hypertension. PVT was completely recanalized with single oral anticoagulant therapy rivaroxaban as initial low molecular weight heparin, enoxaparin administration caused reversible pancytopenia and there is a concern for bleeding and regular monitoring of INR with warfarin in this patient. Keywords: Portal vein thrombosis; Chronic liver disease; Protein S deficiency; Oral anticoagulant; Portal hypertension; Thrombolysis

A case of portal vein thrombosis associated with protein S deficiency

1993 ◽  
Vol 18 (2) ◽  
pp. 258 ◽  
Author(s):  
Bertrand Godeau ◽  
Catherine Leroy-Matheron ◽  
Michèle Gouault-Heilmann ◽  
Annette Schaeffer
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

scholarly journals Recurrent esophagogastric variceal bleeding due to portal vein thrombosis caused by protein S deficiency

2018 ◽  
Vol 06 (11) ◽  
pp. E1283-E1288 ◽  
Author(s):  
Haoxiong Zhou ◽  
Jieying Xuan ◽  
Xianyi Lin ◽  
Yunwei Guo
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Variceal Bleeding ◽  
Endoscopic Therapy ◽  
Protein S ◽  
Protein S Deficiency ◽  
Esophageal Variceal ◽  
Vein Thrombosis ◽  
S Deficiency

Abstract Background and study aims Esophagogastric variceal bleeding (EGVB) is common in patients with portal vein thrombosis (PVT). Hereditary deficiencies in natural anticoagulant proteins, such as protein S, might contribute to PVT. However, recurrent EGVB caused by PVT in patients with protein S deficiency is seldom reported. Herein, we present the case of a 38-year-old man with protein S deficiency complicated with PVT. The patient suffered recurrent EGVB for 7 years. He underwent splenectomy plus pericardial revascularization and sequential endoscopic therapy, including one gastric variceal obturation (GVO) procedure and two esophageal variceal ligations (EVL) to eradicate the varices. Rivaroxaban was administrated to reduce risk of thrombotic events. The patient is currently well without rebleeding after 1 year of follow-up. To our knowledge there is no consensus on management of recurrent EGVB on the basis of thrombophilia complicated with PVT. According to our practice, sequential endoscopic therapy combined with anticoagulant appears to be effective and safe.

scholarly journals A Case of Protein S Deficiency Presented with Superior Mesenteric and Portal Vein Thrombosis

2002 ◽  
Vol 35 (2) ◽  
pp. 184-188 ◽  
Author(s):  
Yoshio Uemura ◽  
Kenji Kobayashi ◽  
Taichi Koyama ◽  
Naofumi Kagara ◽  
Yosuke Seki ◽  
...  
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

scholarly journals A Case of Ileal Necrosis caused by Superior Mesenteric and Portal Vein Thrombosis associated with Protein S Deficiency

2009 ◽  
Vol 42 (11) ◽  
pp. 1717-1722
Author(s):  
Kei Yonezawa ◽  
Jun Nakagawa ◽  
Toshihiko Gotoh ◽  
Motoko Harigai ◽  
Toshiki Kobayashi ◽  
...  
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

scholarly journals A Case of Portal Vein Thrombosis due to Protein S Deficiency which Avoided Intestinal Resection

2021 ◽  
Vol 82 (5) ◽  
pp. 891-895
Author(s):  
Kyohei KAWASAKI ◽  
Takuji KAGIYA ◽  
Kenta OGASAWARA ◽  
Ryuichi TAKIGAMI ◽  
Takao YAMAMOTO ◽  
...  
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Intestinal Resection ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

scholarly journals Laparoscopic splenectomy and proximal splenorenal shunt for portal hypertension due to portal vein thrombosis in a patient with protein S deficiency

2021 ◽  
Vol 41 (1) ◽  
pp. 48
Author(s):  
Claudia Alvizuri Gómez ◽  
Diego Romaní Pozo ◽  
Guillermo Herrera Chávez ◽  
Carla Laso Suárez ◽  
Félix Carrasco Mascaro ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Laparoscopic Splenectomy ◽  
Protein S ◽  
Splenorenal Shunt ◽  
Minor Bleeding ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

Portal vein thrombosis (PVT) is a rare condition in the general population that develops serious complications if left untreated for long time. We present a case of a 29-year-old woman who developed PVT due to protein S deficiency versus neonatal funiculitis. Over time, the patient developed upper gastrointestinal bleeding due to esophageal varices and hypersplenism with splenic sequestration that caused minor bleeding episodes. Laparoscopic splenectomy and proximal splenorenal shunt with distal pancreatectomy due to aneurysmal dilatations of the splenic artery were successfully performed to avoid mayor progression of portal hypertension. Patient was discharged with indefinite anticoagulation and after surgery platelets raised 3 3 ectomy and proximal splenorenal shunt for portal hypertension due to portal vein ombosis is an adequate surgery procedure which should be applied in these medical cases.

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