scholarly journals A case report on aggressive giant cell tumor of greater trochanter: a divergent site

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Rohan Kumar Singh ◽  
PratapSingh Hanuman Parihar ◽  
Gaurav Vedprakash Mishra ◽  
Rajasbala Pradeep Dhande ◽  
Prerna Anup Patwa
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Needle Aspiration ◽  
Cell Tumor ◽  
Long Bone ◽  
Greater Trochanter ◽  
Giant Cell Tumors ◽  
Additional Information ◽  
Benign Nature ◽  
Needle Aspiration Cytology

Abstract Background Giant cell tumor is a tumor of benign nature which usually arises in the long bone, but it can also be seen at unusual sites. Only few cases have been reported so far regarding involvement of greater trochanter of the femur as it is a very divergent site for giant cell tumors; our case is one of them. Giant cell tumors are seen in 20–40 years of age in the metaepiphyseal regions of the long bones. If femur has to be involved, it is in the distal end usually. Case presentation We present a case of a 45-year-old female with chief complains of swelling and left hip pain since over a month. Magnetic resonance imaging was done where the location and extent of the tumor was found. What makes this case interesting is that on fine needle aspiration cytology the lesion showed multinucleated giant osteoclasts in the background of osseous matrix of spindle cells suggesting Giant cell tumor. Conclusion It is sometimes tricky to make a diagnosis of these lesions on imaging as the typical features may not be present, and hence, in such circumstances helping the clinicians with additional information like location, extent, margins is of utmost importance.

Giant Cell Tumor of the Larynx

1998 ◽  
Vol 107 (8) ◽  
pp. 729-732 ◽  
Author(s):  
Kenneth O. Devaney ◽  
Alfio Ferlito ◽  
Alessandra Rinaldo
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Sarcomatoid Carcinoma ◽  
Cell Tumor ◽  
Long Bone ◽  
Giant Cell Tumors ◽  
Tentative Diagnosis ◽  
True Neoplasm

Among the more uncommon tumors that may sometimes be encountered in the laryngeal region is the recently described giant cell tumor of the larynx. This lesion is a true neoplasm, presumably of the fibrohistiocytic series. Histologically, it closely resembles the more familiar true giant cell tumor of long bone. The laryngeal giant cell tumors appear, to date, to be nonmetastasizing lesions; it is possible that they may recur locally if incompletely excised (although this remains to be demonstrated). In view of the rarity of these tumors, a tentative diagnosis of such a neoplasm should always prompt consideration of other (more frequently encountered) differential diagnostic possibilities, including cytologically malignant giant cell-rich tumors such as malignant fibrous histiocytoma and sarcomatoid carcinoma.

Fine Needle Aspiration Cytology of Diffuse-Type Tenosynovial Giant Cell Tumors

2017 ◽  
Vol 61 (2) ◽  
pp. 160-164 ◽  
Author(s):  
Zimin Zhao ◽  
Cherie Paquette ◽  
Akeesha A. Shah ◽  
Kristen A. Atkins ◽  
Henry F. Frierson
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Cell Tumor ◽  
Diffuse Type ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Tenosynovial giant cell tumor (TSGCT), also known as giant cell tumor of tendon sheath or pigmented villonodular synovitis, is the most common benign tumor of the tendon and synovium. The intra-articular diffuse type can present as a large infiltrative mass involving adjacent soft tissue and sometimes causes secondary destruction of bone, which leads to radiographic and clinical concern for malignancy. The tumor may also be purely extra-articular. Case: Here, we report the fine needle aspiration cytology findings of 2 cases of diffuse-type TSGCT with large mononuclear cells with eccentric nuclei, finely granular cytoplasm, and a peripheral well-defined cytoplasmic rim of hemosiderin (“ladybird cells”). Conclusion: Although the presence of ladybird cells has been described in tissue sections of TSGCT, their identification in cytological specimens has not been reported to our knowledge. When observed, their presence may aid in differentiating TSGCT from other lesions with multinucleated osteoclast-type giant cells occurring at or near joints.

scholarly journals Giant cell tumor of patella

2013 ◽  
Vol 34 (3) ◽  
pp. 58-60
Author(s):  
S Paudel ◽  
P Kayastha ◽  
P Pokhrel ◽  
A Shah ◽  
RK Ghimire ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Articular Surface ◽  
Needle Aspiration ◽  
Cell Tumor ◽  
Skeletal Maturation ◽  
Institute Of Medicine ◽  
Aspiration Cytology ◽  
Needle Aspiration Cytology ◽  
The Right

Giant cell tumor of bone also known as osteoclastoma is a distinct clinical, roentgenographic and pathologic entity with specific characteristics. It is a benign but locally aggressive neoplasm of the epiphyseal or metaphyseal-epiphyseal region of long tubular bones extending to the articular surface. It usually occurs after skeletal maturation and is one of the rare bone tumors that more frequently affects women. We report here a case of giant cell tumor originating from the right patella diagnosed on ne needle aspiration cytology. DOI: http://dx.doi.org/10.3126/joim.v34i3.8920   Journal of Institute of Medicine, December, 2012; 34:58-60

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