scholarly journals Early Goal-directed Therapy, Corticosteroid, and Recombinant Human Activated Protein C for the Treatment of Severe Sepsis and Septic Shock in the Emergency Department

2006 ◽  
Vol 13 (1) ◽  
pp. 109-113 ◽  
Author(s):  
H. Bryant Nguyen ◽  
Stephen W. Corbett ◽  
Kevin Menes ◽  
Thomas Cho ◽  
Jennifer Daugharthy ◽  
...  
Keyword(s):  
Emergency Department ◽  
Septic Shock ◽  
Severe Sepsis ◽  
Protein C ◽  
Activated Protein C ◽  
Goal Directed Therapy ◽  
Early Goal Directed Therapy ◽  
Sepsis And Septic Shock

EARLY GOAL DIRECTED THERAPY, CORTICOSTEROID, AND ACTIVATED PROTEIN C FOR SEVERE SEPSIS/SEPTIC SHOCK IN THE EMERGENCY DEPARTMENT

2004 ◽  
Vol 32 (Supplement) ◽  
pp. A159
Author(s):  
H Bryant Nguyen ◽  
Walter Klein ◽  
Stephen W Corbett ◽  
Robin Clark ◽  
William A Wittlake
Keyword(s):  
Emergency Department ◽  
Septic Shock ◽  
Severe Sepsis ◽  
Protein C ◽  
Activated Protein C ◽  
Goal Directed Therapy ◽  
Early Goal Directed Therapy

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

2018 ◽  
pp. 104-108
Keyword(s):  
Intensive Care Unit ◽  
Emergency Department ◽  
Septic Shock ◽  
Severe Sepsis ◽  
Intensive Care ◽  
Oxygen Demand ◽  
Goal Directed Therapy ◽  
Early Goal Directed Therapy ◽  
Study Results ◽  
Sepsis And Septic Shock

This case focuses on detecting sepsis through early goal-directed therapies by asking the question: Does aggressive correction of hemodynamic disturbances in the early stages of sepsis improve outcomes? Early goal-directed therapies are aimed at restoring a balance between oxygen delivery and oxygen demand. Patients included in the study were adults presenting to the emergency room with severe sepsis or septic shock. Study results indicated that most patients with severe sepsis or septic shock should be managed with aggressive hemodynamic monitoring and support immediately on presentation in the emergency department (or, if this is not possible, in the intensive care unit) for 6 hours or until there is resolution of hemodynamic disturbances.

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