Herniated lumbar disc disease in patients with malignancy.

1987 ◽  
Vol 5 (4) ◽  
pp. 667-671 ◽  
Author(s):  
R Goodkin ◽  
B I Carr ◽  
R G Perrin

Six patients with cancer presented with signs and symptoms of a lumbar herniated disc syndrome due to a herniated lumbar disc. The differential diagnosis and literature are reviewed. In four of the six, the patients' complaints were attributed to the malignancy, with delay in diagnosis and institution of appropriate therapy. In two of the patients, treatment was administered for presumed spinal metastasis with radiation therapy and/or chemotherapy with castration before the correct diagnosis was made. Surgery was performed on all six patients confirming the diagnosis of a herniated lumbar disc at the involved level and relieving the patients' pain.

Spine ◽  
2011 ◽  
Vol 36 (19) ◽  
pp. 1541-1546 ◽  
Author(s):  
Inge Gregersen Sørensen ◽  
Peter Jacobsen ◽  
Finn Gyntelberg ◽  
Poul Suadicani

2013 ◽  
Vol 19 (6) ◽  
pp. 767-773 ◽  
Author(s):  
Martin Nikolaus Stienen ◽  
Werner Surbeck ◽  
Ulrich Tröhler ◽  
Gerhard Hildebrandt

The understanding of lumbar spine pathologies made substantial progress at the turn of the twentieth century. The authors review the original publication of Otto Veraguth in 1929 reporting on the successful resection of a herniated lumbar disc, published exclusively in the German language. His early report is put into the historical context, and its impact on the understanding of pathologies of the intervertebral disc (IVD) is estimated. The Swiss surgeon and Nobel Prize laureate Emil Theodor Kocher was among the first physicians to describe the traumatic rupture of the IVD in 1896. As early as 1909 Oppenheim and Krause published 2 case reports on surgery for a herniated lumbar disc. Goldthwait was the first physician to delineate the etiopathogenes is between annulus rupture, symptoms of sciatica, and neurological signs in his publication of 1911. Further publications by Middleton and Teacher in 1911 and Schmorl in 1929 added to the understanding of lumbar spinal pathologies. In 1929, the Swiss neurologist Veraguth (surgery performed by Hans Brun) and the American neurosurgeon Walter Edward Dandy both published their early experiences with the surgical therapy of a herniated lumbar disc. Veraguth's contribution, however, has not been appreciated internationally to date. The causal relationship between lumbar disc pathology and sciatica remained uncertain for some years to come. The causal relationship was not confirmed until Mixter and Barr's landmark paper in 1934 describing the association of sciatica and lumbar disc herniation, after which the surgical treatment became increasingly popular. Veraguth was among the first physicians to report on the clinical course of a patient with successful resection of a herniated lumbar disc. His observations should be acknowledged in view of the limited experience and literature on this ailment at that time.


2017 ◽  
Vol 51 (2) ◽  
pp. 149-155 ◽  
Author(s):  
Harsha A. Huliyappa ◽  
Rakesh Kumar Singh ◽  
Sunil Kumar Singh ◽  
Manish Jaiswal ◽  
Somil Jaiswal ◽  
...  

Spine ◽  
1996 ◽  
Vol 21 (14) ◽  
pp. 1653-1655 ◽  
Author(s):  
John L. OʼDonnell ◽  
Amy L. OʼDonnell

1986 ◽  
Vol 64 (4) ◽  
pp. 613-616 ◽  
Author(s):  
Robert G. Fisher ◽  
John W. Bromley ◽  
George L. Becker ◽  
Mark Brown ◽  
Vert Mooney

✓ Of 410 patients with refractory herniated lumbar disc disease treated with intradiscal collagenase, 82 (20%) did not respond to enzyme treatment and subsequently underwent surgery. Failure to improve in 6 to 8 weeks was the predominant cause for surgical intervention (53 patients). Increased pain (18 patients), progressing neurological deficit (10 patients), and disc-space infection (one patient) were the other indications for surgery. At surgery, extrusions and/or sequestrations were found in 46 patients, undigested protrusions in 16 patients, and other causes of treatment failure in 14 patients. Six patients had normal findings. There was no evidence of adverse enzyme activity on the surrounding structures. Surgical results showed an overall success rate of 87%, and did not appear to be compromised by the previous enzyme therapy.


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