A phase I dose-escalation trial evaluating ARQ 197 administered in combination with sorafenib in adult patients (pts) with advanced solid tumors.

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. 3024-3024 ◽  
Author(s):  
A. A. Adjei ◽  
J. A. Sosman ◽  
G. K. Dy ◽  
W. Ma ◽  
G. J. Fetterly ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Adult Patients ◽  
Advanced Solid Tumors ◽  
Arq 197

scholarly journals A Phase I Dose-Escalation Study of Tivantinib (ARQ 197) in Adult Patients with Metastatic Solid Tumors

2011 ◽  
Vol 17 (24) ◽  
pp. 7754-7764 ◽  
Author(s):  
Lee S. Rosen ◽  
Neil Senzer ◽  
Tarek Mekhail ◽  
Ram Ganapathi ◽  
Feng Chai ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Adult Patients ◽  
Dose Escalation Study ◽  
Arq 197

scholarly journals Phase I dose escalation study of MK-0457, a novel Aurora kinase inhibitor, in adult patients with advanced solid tumors

2010 ◽  
Vol 67 (2) ◽  
pp. 305-314 ◽  
Author(s):  
Anne M. Traynor ◽  
Maureen Hewitt ◽  
Glenn Liu ◽  
Keith T. Flaherty ◽  
Jason Clark ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Adult Patients ◽  
Advanced Solid Tumors ◽  
Aurora Kinase Inhibitor ◽  
Dose Escalation Study

A phase I, dose escalation, pharmacodynamic, pharmacokinetic, and food-effect study of α2 integrin inhibitor E7820 in patients with advanced solid tumors

2016 ◽  
Vol 34 (3) ◽  
pp. 329-337 ◽  
Author(s):  
B. Milojkovic Kerklaan ◽  
S. Slater ◽  
M. Flynn ◽  
A. Greystoke ◽  
P. O. Witteveen ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Food Effect ◽  
Effect Study ◽  
Advanced Solid Tumors ◽  
Integrin Inhibitor

A phase I dose escalation and pharmacokinetic study of vatalanib (PTK787/ZK 222584) in combination with paclitaxel in patients with advanced solid tumors

2009 ◽  
Vol 66 (3) ◽  
pp. 441-448 ◽  
Author(s):  
E. Gabriela Chiorean ◽  
Srikar Malireddy ◽  
Anne E. Younger ◽  
David R. Jones ◽  
Mary-Jane Waddell ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Dose Escalation ◽  
Advanced Solid Tumors

scholarly journals Phase I Dose-Escalation and -Expansion Study of Telisotuzumab (ABT-700), an Anti–c-Met Antibody, in Patients with Advanced Solid Tumors

2020 ◽  
Vol 19 (5) ◽  
pp. 1210-1217 ◽  
Author(s):  
John H. Strickler ◽  
Patricia LoRusso ◽  
Ravi Salgia ◽  
Yoon-Koo Kang ◽  
Chia Jui Yen ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Advanced Solid Tumors

A Phase I Dose–Escalation Study of Regorafenib (BAY 73–4506), an Inhibitor of Oncogenic, Angiogenic, and Stromal Kinases, in Patients with Advanced Solid Tumors

2012 ◽  
Vol 18 (9) ◽  
pp. 2658-2667 ◽  
Author(s):  
Klaus Mross ◽  
Annette Frost ◽  
Simone Steinbild ◽  
Susanne Hedbom ◽  
Martin Büchert ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study

scholarly journals Sunitinib in combination with docetaxel in patients with advanced solid tumors: a phase I dose-escalation study

2009 ◽  
Vol 66 (4) ◽  
pp. 669-680 ◽  
Author(s):  
Francisco Robert ◽  
Alan Sandler ◽  
Joan H. Schiller ◽  
Glenn Liu ◽  
Karen Harper ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study
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