Safety and efficacy of neoadjuvant combination of hepatic artery infusion (HAI) of irinotecan, 5-fluorouracil, and oxaliplatin with intravenous (iv) cetuximab in patients with unresectable liver metastases from colorectal cancer (CRC): Interim report from OPTILIV—A European multicenter phase II trial.

M. Ducreux; P. Rougier; D. Smith; C. N. J. Focan; P. F. Innominato; M. Bouchahda; Y. Ajavon; D. Castaing; T. De Baere; A. Karaboué; C. Lepere; V. Boige; R. Adam; F. Levi

doi:10.1200/jco.2011.29.15_suppl.e14102

Safety and efficacy of neoadjuvant combination of hepatic artery infusion (HAI) of irinotecan, 5-fluorouracil, and oxaliplatin with intravenous (iv) cetuximab in patients with unresectable liver metastases from colorectal cancer (CRC): Interim report from OPTILIV—A European multicenter phase II trial.

Journal of Clinical Oncology ◽

10.1200/jco.2011.29.15_suppl.e14102 ◽

2011 ◽

Vol 29 (15_suppl) ◽

pp. e14102-e14102

Author(s):

M. Ducreux ◽

P. Rougier ◽

D. Smith ◽

C. N. J. Focan ◽

P. F. Innominato ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Hepatic Artery ◽

Phase Ii ◽

Phase Ii Trial ◽

Hepatic Artery Infusion ◽

Interim Report ◽

Safety And Efficacy ◽

Multicenter Phase ◽

Unresectable Liver Metastases

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Safety and Efficacy of Intravenous Cetuximab (CET) and Hepatic Artery Infusion of Irinotecan, 5-Fluorouracil and Oxaliplatin in Patients with Unresectable Liver Metastases from Wt Kras Colorectal Cancer (CRC): Results from Optiliv European Phase II Trial

Annals of Oncology ◽

10.1016/s0923-7534(20)33179-3 ◽

2012 ◽

Vol 23 ◽

pp. ix194

Author(s):

F. Levi ◽

V. Boige ◽

P. Rougier ◽

M. Hebbar ◽

D. Smith ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Hepatic Artery ◽

Phase Ii ◽

Phase Ii Trial ◽

Hepatic Artery Infusion ◽

Safety And Efficacy ◽

Unresectable Liver Metastases

Download Full-text

Optimal control of liver metastases with intravenous cetuximab and hepatic artery infusion of three-drug chemotherapy in patients with liver-only metastases from colorectal cancer: A European multicenter phase II trial.

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.tps198 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. TPS198-TPS198 ◽

Cited By ~ 1

Author(s):

F. Levi ◽

M. Bouchahda ◽

M. Ducreux ◽

A. Karaboué ◽

C. N. Focan ◽

...

Keyword(s):

Colorectal Cancer ◽

Optimal Control ◽

Liver Metastases ◽

Hepatic Artery ◽

Phase Ii ◽

Phase Ii Trial ◽

Hepatic Artery Infusion ◽

Multicenter Phase

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Pharmacokinetic-pharmacodynamic analysis of hepatic artery infusion of three-drug chronomodulated chemotherapy and intravenous cetuximab in patients with liver metastases from colorectal cancer registered in OPTILIV, a European multicenter phase II trial.

Journal of Clinical Oncology ◽

10.1200/jco.2011.29.15_suppl.e14134 ◽

2011 ◽

Vol 29 (15_suppl) ◽

pp. e14134-e14134

Author(s):

F. Levi ◽

A. Karaboué ◽

M. Etienne-Grimaldi ◽

E. Chatelut ◽

P. F. Innominato ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Hepatic Artery ◽

Phase Ii ◽

Phase Ii Trial ◽

Hepatic Artery Infusion ◽

Multicenter Phase ◽

Pharmacodynamic Analysis

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Modified FOLFOXIRI With or Without Cetuximab as Conversion Therapy in Patients with RAS / BRAF Wild‐Type Unresectable Liver Metastases Colorectal Cancer: The FOCULM Multicenter Phase II Trial

The Oncologist ◽

10.1634/theoncologist.2020-0563 ◽

2020 ◽

Author(s):

Huabin Hu ◽

Kun Wang ◽

Meijin Huang ◽

Liang Kang ◽

Wei Wang ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Phase Ii ◽

Phase Ii Trial ◽

Wild Type ◽

Conversion Therapy ◽

Multicenter Phase ◽

Unresectable Liver Metastases

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Impact of early tumor response on prognostic of patients with unresectable liver metastases from wt-KRAS colorectal cancer (LM-CRC) treated with hepatic artery infusion of irinotecan, 5-fluorouracil and oxaliplatin plus intravenous cetuximab after failure of systemic chemotherapy (European Phase II OPTILIV).

Journal of Clinical Oncology ◽

10.1200/jco.2016.34.15_suppl.e15036 ◽

2016 ◽

Vol 34 (15_suppl) ◽

pp. e15036-e15036

Author(s):

Mohamed Bouchahda ◽

Valerie Boige ◽

Denis Michel Smith ◽

Abdoulaye KarabouÃ© ◽

Mohamed Hebbar ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Hepatic Artery ◽

Phase Ii ◽

Systemic Chemotherapy ◽

Tumor Response ◽

Hepatic Artery Infusion ◽

Unresectable Liver Metastases ◽

Early Tumor Response ◽

Early Tumor

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Percutaneous hepatic perfusion with melphalan in treating unresectable liver metastases of colorectal cancer and uveal melanoma: A phase ii trial

HPB ◽

10.1016/j.hpb.2016.01.194 ◽

2016 ◽

Vol 18 ◽

pp. e734

Author(s):

E.M. de Leede ◽

M.C. Burgmans ◽

C.H. Martini ◽

J. Vuyk ◽

F.G.J. Tyl ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Uveal Melanoma ◽

Phase Ii ◽

Phase Ii Trial ◽

Hepatic Perfusion ◽

Unresectable Liver Metastases ◽

Percutaneous Hepatic Perfusion

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Resection of previously unresectable liver metastases from colorectal cancer (LMCRC) after chemotherapy (CT) with CPT-11/L-OHP/LV5FU (Folfirinox): A prospective phase II trial

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.14_suppl.3613 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3613-3613 ◽

Cited By ~ 16

Author(s):

F. Quenet ◽

B. Nordlinger ◽

M. Rivoire ◽

J. R. Delpero ◽

G. Portier ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Phase Ii ◽

Phase Ii Trial ◽

Prospective Phase ◽

Unresectable Liver Metastases

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Early tumour response as a survival predictor in previously- treated patients receiving triplet hepatic artery infusion and intravenous cetuximab for unresectable liver metastases from wild-type KRAS colorectal cancer

European Journal of Cancer ◽

10.1016/j.ejca.2016.09.011 ◽

2016 ◽

Vol 68 ◽

pp. 163-172 ◽

Cited By ~ 5

Author(s):

Mohamed Bouchahda ◽

Valérie Boige ◽

Denis Smith ◽

Abdoulaye Karaboué ◽

Michel Ducreux ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Hepatic Artery ◽

Tumour Response ◽

Hepatic Artery Infusion ◽

Wild Type ◽

Unresectable Liver Metastases ◽

Previously Treated Patients ◽

Previously Treated ◽

Survival Predictor

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Four-year survival in patients (pts) undergoing liver surgery after neoadjuvant triplet hepatic artery infusion (HAI) and intravenous cetuximab (IV-CET) for previously treated and unresectable liver metastases from kras wt colorectal cancer (LM-CRC) (European trial OPTILIV, NCT00852228).

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.3589 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 3589-3589 ◽

Cited By ~ 1

Author(s):

Francis Levi ◽

Michel Ducreux ◽

Denis Michel Smith ◽

Mohamed Hebbar ◽

Céline Lepère ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Hepatic Artery ◽

Liver Surgery ◽

Hepatic Artery Infusion ◽

Unresectable Liver Metastases ◽

Previously Treated ◽

European Trial

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Prolonged continuous hepatic artery infusion with interleukin-2 in unresectable liver metastases of colorectal cancer: A phase IA—B study

Annals of Oncology ◽

10.1093/oxfordjournals.annonc.a010579 ◽

1996 ◽

Vol 7 (3) ◽

pp. 317-319

Author(s):

S.H. Goey ◽

A.M.M. Eggermont ◽

R. Oskam ◽

Th. Wiggers ◽

R.L.H Bolhuis ◽

...

Keyword(s):

Colorectal Cancer ◽

Liver Metastases ◽

Hepatic Artery ◽

Interleukin 2 ◽

Hepatic Artery Infusion ◽

Unresectable Liver Metastases

Download Full-text