Human systems integration (HSI) ensures human strengths and limitations are taken into consideration throughout the system design, development, and acquisition process. Regardless of the organization in which HSI practitioners work, the nature of their work involves interfacing with various organizational, system, and user stakeholders. The cross-service DoD and industry panelists will briefly discuss their diverse experiences and perspectives regarding human systems integration, working with various HSI stakeholders, and personal lessons learned (i.e., successes and challenges). The sharing of cross-service and industry lessons learned aims to prepare other HSI practitioners to effectively work and interact with various stakeholders. This knowledge exchange also encourages continued collaboration between HSI practitioners and aims to expand HSI across contexts, environments, and system stakeholders.