Pharmacological Strategies for Uterine Relaxation

2019 ◽  
pp. 401-431
Author(s):  
Michael Hollingsworth ◽  
Sandra J. Downing ◽  
Josephine M. S. Cheuk ◽  
Ian T. Piper ◽  
Sarah J. Hughes
Keyword(s):  
Uterine Relaxation

Letter: The use of intravenous nitroglycerin for emergency cervico-uterine relaxation

1997 ◽  
Vol 76 (3) ◽  
pp. 287-288 ◽  
Author(s):  
Ph. Dufour ◽  
D. Vinatier ◽  
G. Orazi ◽  
A. S. Ducloy
Keyword(s):  
Intravenous Nitroglycerin ◽  
Uterine Relaxation

scholarly journals The Successful Use of Nitroglycerin for Uterine Hyperstimulation with Fetal Heart Rate Abnormality Caused by a Controlled-Release Dinoprostone Vaginal Delivery System (PROPESS): A Case Report

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 478
Author(s):  
Sho Takakura ◽  
Hiroaki Tanaka ◽  
Naosuke Enomoto ◽  
Shintaro Maki ◽  
Tomoaki Ikeda
Keyword(s):  
Heart Rate ◽  
Controlled Release ◽  
Vaginal Delivery ◽  
Delivery System ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Cervical Ripening ◽  
Emergency Cesarean ◽  
Uterine Hyperstimulation ◽  
Uterine Relaxation

The PROPESS, a controlled-release dinoprostone vaginal delivery system, is a pharmacological cervical ripening intervention and promotes cervical change causing uterine contraction. During insertion of the PROPESS, uterine hyperstimulation could occur and result in fetal heart rate (FHR) abnormality. We report a case of uterine hyperstimulation accompanied with FHR abnormality caused by the PROPESS in a pregnant woman. Postural change, oxygenation, fluid infusion, and the immediate PROPESS removal were ineffective to address the adverse event, so we administered nitroglycerin for acute uterine relaxation. The nitroglycerin resulted in uterine relaxation, and the FHR abnormality was resolved immediately, thereby preventing an emergency cesarean section. Therefore, nitroglycerin could be considered an effective option for uterine hyperstimulation accompanied with FHR abnormality caused by the PROPESS.

scholarly journals The Contrasting Effects of Enflurane on Transplacental Exchange after Methohexitone and Ketamine Induction of Anaesthesia for Caesarean Section

1978 ◽  
Vol 6 (3) ◽  
pp. 239-242 ◽  
Author(s):  
J. W. Downing ◽  
P. J. C. Houlton ◽  
J. G. Brock-Utne ◽  
R. J. R. Buley
Keyword(s):  
Caesarean Section ◽  
Beneficial Effect ◽  
General Anaesthesia ◽  
Elective Caesarean Section ◽  
Volatile Agent ◽  
Inhalational Agent ◽  
Induction Of Anaesthesia ◽  
Uterine Relaxation

Supplementation of general anaesthesia with enflurane 0.6% before delivery of the foetus by elective Caesarean section, produced contrasting effects after methohexitone and ketamine administration. Enflurane, an inhalational agent causing vasodilation and uterine relaxation, enhanced maternal to foetal transplacental exchange following methohexitone induction of narcosis. This beneficial effect of the volatile agent was not seen after ketamine, a vasoconstrictor drug which stimulates myometrial contraction.

Use of Nitroglycerin for Uterine Relaxation

1998 ◽  
Vol 53 (9) ◽  
pp. 559-565 ◽  
Author(s):  
Graeme N. Smith ◽  
James F. Brien
Keyword(s):  
Uterine Relaxation

Beta-3 versus beta-2 adrenergic agonists and preterm labour: in vitro uterine relaxation effects

2001 ◽  
Vol 108 (6) ◽  
pp. 605-609 ◽  
Author(s):  
Michael C Dennedy ◽  
Anne M Friel ◽  
Francois Gardeil ◽  
John J Morrison
Keyword(s):  
Preterm Labour ◽  
Adrenergic Agonists ◽  
Relaxation Effects ◽  
Beta 2 ◽  
Uterine Relaxation

Evidence that 5β-progestins produce uterine relaxation by diminishing cellular calcium permeability

1985 ◽  
Vol 6 (1) ◽  
pp. 103-107 ◽  
Author(s):  
Carlos Kubli-Garfias ◽  
Pilar Ortega-Suárez ◽  
Carlos Hoyo-Vadillo ◽  
Héctor Ponce-Monter
Keyword(s):  
Cellular Calcium ◽  
Calcium Permeability ◽  
Uterine Relaxation
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