Active Transport of Sodium and Potassium

2020 ◽  
pp. 455-480
Author(s):  
Jack H. Kaplan
1974 ◽  
Vol 241 (2) ◽  
pp. 359-372 ◽  
Author(s):  
Conrad E. Johanson ◽  
Donal J. Reed ◽  
Dixon M. Woodbury

1960 ◽  
Vol 199 (1) ◽  
pp. 28-30 ◽  
Author(s):  
Oswald Dawkins ◽  
David F. Bohr

When the rat aorta is excised and placed in a bath of Krebs' solution it loses over two-thirds of its potassium and gains roughly an equivalent amount of sodium within the first 15 seconds. If the aorta is placed in rat plasma instead of Krebs' solution, a similar change occurs. These rapid changes in aorta electrolyte composition do not occur when the whole rat is perfused with Krebs' solution. It is concluded that in the handling involved in the removal of the aorta its cell membrane barriers are altered in such a way that they no longer maintain the normal transmembrane gradients of these cations. After 2 minutes in the bath the potassium in the aorta gradually increases and its sodium decreases suggesting that the cell membrane has regained its characteristics as a barrier and is capable of maintaining sodium and potassium gradients established by an active transport system.


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