scholarly journals Comparison of Anterior Cerebral Artery Blood Flow Velocity and Cerebral Blood Flow during Hypoxia

1985 ◽  
Vol 19 (1) ◽  
pp. 67-70 ◽  
Author(s):  
Adam A Rosenberg ◽  
Vinodh Narayanan ◽  
M Douglas Jones
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Blood Flow Velocity ◽  
Anterior Cerebral Artery ◽  
Artery Blood Flow

Multimodal Quantitation of the Effects of Endovascular Therapy for Vasospasm on Cerebral Blood Flow, Transcranial Doppler Ultrasonographic Velocities, and Cerebral Artery Diameters

Neurosurgery ◽  
2002 ◽  
Vol 51 (1) ◽  
pp. 30-43 ◽  
Author(s):  
Rod J. Oskouian ◽  
Neil A. Martin ◽  
Jae Hong Lee ◽  
Thomas C. Glenn ◽  
Donald Guthrie ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Middle Cerebral Artery ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Endovascular Therapy ◽  
Balloon Angioplasty ◽  
Transcranial Doppler ◽  
Blood Flow Velocity ◽  
Artery Blood Flow

Abstract OBJECTIVE The goal of this study was to quantify the effects of endovascular therapy on vasospastic cerebral vessels. METHODS We reviewed the medical records for 387 patients with ruptured intracranial aneurysms who were treated at a single institution (University of California, Los Angeles) between May 1, 1993, and March 31, 2001. Patients who developed cerebral vasospasm and underwent cerebral arteriographic, transcranial Doppler ultrasonographic, and cerebral blood flow (CBF) studies before and after endovascular therapy for cerebral arterial spasm (vasospasm) were included in this study. RESULTS Forty-five patients fulfilled the aforementioned criteria and were treated with either papaverine infusion, papaverine infusion with angioplasty, or angioplasty alone. After balloon angioplasty (12 patients), CBF increased from 27.8 ± 2.8 ml/100 g/min to 28.4 ± 3.0 ml/100 g/min (P = 0.87); the middle cerebral artery blood flow velocity was 157.6 ± 9.4 cm/s and decreased to 76.3 ± 9.3 cm/s (P < 0.05), with a mean increase in cerebral artery diameters of 24.4%. Papaverine infusion (20 patients) transiently increased the CBF from 27.5 ± 2.1 ml/100 g/min to 38.7 ± 2.8 ml/100 g/min (P < 0.05) and decreased the middle cerebral artery blood flow velocity from 109.9 ± 9.1 cm/s to 82.8 ± 8.6 cm/s (P < 0.05). There was a mean increase in vessel diameters of 30.1% after papaverine infusion. Combined treatment (13 patients) significantly increased the CBF from 33.3 ± 3.2 ml/100 g/min to 41.7 ± 2.8 ml/100 g/min (P < 0.05) and decreased the transcranial Doppler velocities from 148.9 ± 12.7 cm/s to 111.4 ± 10.6 cm/s (P < 0.05), with a mean increase in vessel diameters of 42.2%. CONCLUSION Balloon angioplasty increased proximal vessel diameters, whereas papaverine treatment effectively dilated distal cerebral vessels. In our small series, we observed no correlation between early clinical improvement or clinical outcomes and any of our quantitative or physiological data (CBF, transcranial Doppler velocities, or vessel diameters).

Effect of menopause on cerebral artery blood flow velocity and cerebrovascular reactivity: Systematic review and meta-analysis

Maturitas ◽  
2021 ◽  
Vol 148 ◽  
pp. 24-32
Author(s):  
Stefanie L Ruediger ◽  
Jodie L Koep ◽  
Shelley E Keating ◽  
Faith K Pizzey ◽  
Jeff S Coombes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Flow ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Blood Flow Velocity ◽  
Meta Analysis ◽  
Cerebrovascular Reactivity ◽  
Artery Blood Flow

Direct Cerebral Vasodilatory Effects of Sevoflurane and Isoflurane 

1999 ◽  
Vol 91 (3) ◽  
pp. 677-677 ◽  
Author(s):  
Basil F. Matta ◽  
Karen J. Heath ◽  
Kate Tipping ◽  
Andrew C. Summors
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Middle Cerebral Artery ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Blood Flow Velocity ◽  
End Tidal

Background The effect of volatile anesthetics on cerebral blood flow depends on the balance between the indirect vasoconstrictive action secondary to flow-metabolism coupling and the agent's intrinsic vasodilatory action. This study compared the direct cerebral vasodilatory actions of 0.5 and 1.5 minimum alveolar concentration (MAC) sevoflurane and isoflurane during an propofol-induced isoelectric electroencephalogram. Methods Twenty patients aged 20-62 yr with American Society of Anesthesiologists physical status I or II requiring general anesthesia for routine spinal surgery were recruited. In addition to routine monitoring, a transcranial Doppler ultrasound was used to measure blood flow velocity in the middle cerebral artery, and an electroencephalograph to measure brain electrical activity. Anesthesia was induced with propofol 2.5 mg/kg, fentanyl 2 micro/g/kg, and atracurium 0.5 mg/kg, and a propofol infusion was used to achieve electroencephalographic isoelectricity. End-tidal carbon dioxide, blood pressure, and temperature were maintained constant throughout the study period. Cerebral blood flow velocity, mean blood pressure, and heart rate were recorded after 20 min of isoelectric encephalogram. Patients were then assigned to receive either age-adjusted 0.5 MAC (0.8-1%) or 1.5 MAC (2.4-3%) end-tidal sevoflurane; or age-adjusted 0.5 MAC (0.5-0.7%) or 1.5 MAC (1.5-2%) end-tidal isoflurane. After 15 min of unchanged end-tidal concentration, the variables were measured again. The concentration of the inhalational agent was increased or decreased as appropriate, and all measurements were repeated again. All measurements were performed before the start of surgery. An infusion of 0.01% phenylephrine was used as necessary to maintain mean arterial pressure at baseline levels. Results Although both agents increased blood flow velocity in the middle cerebral artery at 0.5 and 1.5 MAC, this increase was significantly less during sevoflurane anesthesia (4+/-3 and 17+/-3% at 0.5 and 1.5 MAC sevoflurane; 19+/-3 and 72+/-9% at 0.5 and 1.5 MAC isoflurane [mean +/- SD]; P<0.05). All patients required phenylephrine (100-300 microg) to maintain mean arterial pressure within 20% of baseline during 1.5 MAC anesthesia. Conclusions In common with other volatile anesthetic agents, sevoflurane has an intrinsic dose-dependent cerebral vasodilatory effect. However, this effect is less than that of isoflurane.

scholarly journals Dynamic Regulation of Middle Cerebral Artery Blood Flow Velocity in Aging and Hypertension

Stroke ◽  
2000 ◽  
Vol 31 (8) ◽  
pp. 1897-1903 ◽  
Author(s):  
Lewis A. Lipsitz ◽  
Seiji Mukai ◽  
Jason Hamner ◽  
Margaret Gagnon ◽  
Viken Babikian
Keyword(s):  
Blood Flow ◽  
Middle Cerebral Artery ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Blood Flow Velocity ◽  
Artery Blood Flow ◽  
Dynamic Regulation
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