Severe Hypercalcemia in a Patient with Liver Metastasis of Unknown Primary: An Unusual Case of Coexistent Primary Hyperparathyroidism (PHPT) and Humoral Hypercalcemia of Malignancy (HHM)

2011 ◽  
pp. P3-103-P3-103
Author(s):  
Hiba N Abou Assi ◽  
Thomas J Weber ◽  
Jennifer M Perkins
Keyword(s):  
Liver Metastasis ◽  
Primary Hyperparathyroidism ◽  
Unusual Case ◽  
Unknown Primary ◽  
Humoral Hypercalcemia Of Malignancy ◽  
Hypercalcemia Of Malignancy ◽  
Humoral Hypercalcemia ◽  
Severe Hypercalcemia

scholarly journals Association of primary hyperparathyroidism and humoral hypercalcemia of malignancy in a patient with clear cell renal carcinoma

2015 ◽  
Vol 59 (1) ◽  
pp. 84-88 ◽  
Author(s):  
Letícia da Silva Gomes ◽  
Carolina A. M. Kulak ◽  
Tatiana Munhoz da Rocha Lemos Costa ◽  
Evandro Cezar Guerreiro Vasconcelos ◽  
Maurício de Carvalho ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Renal Carcinoma ◽  
Clear Cell ◽  
Clear Cell Renal Carcinoma ◽  
Humoral Hypercalcemia Of Malignancy ◽  
Hypercalcemia Of Malignancy ◽  
Humoral Hypercalcemia ◽  
Cell Renal Carcinoma

scholarly journals Hypercalcemic Crisis

2001 ◽  
Vol 12 (suppl 1) ◽  
pp. S3-S9
Author(s):  
REINHARD ZIEGLER
Keyword(s):  
Primary Hyperparathyroidism ◽  
Serum Calcium ◽  
Fatal Outcome ◽  
Humoral Hypercalcemia Of Malignancy ◽  
Hypercalcemia Of Malignancy ◽  
Hypercalcemic Crisis ◽  
Humoral Hypercalcemia ◽  
First Case ◽  
Threatening Condition ◽  
Life Threatening

Abstract. Hypercalcemia may decompensate from a more or less chronic status into a critical and life-threatening condition, hypercalcemic crisis. In the majority of cases, primary hyperparathyroidism is the cause; humoral hypercalcemia of malignancy or rarer conditions of hypercalcemia will decompensate less often. The leading symptoms that characterize the crisis are oliguria and anuria as well as somnolence and coma. After a hypercalcemic crisis is recognized, an emergency diagnostic program has to be followed either to prove or to exclude primary hyperparathyroidism. In the first case, surgical neck exploration is the only way to avoid fatal outcome. The diagnostic program should be performed within hours; during this time, serum calcium should be lowered. Treatment of choice is hemodialysis against a calcium-free dialysate. Bisphosphonates could be useful as adjuvant drugs.

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