scholarly journals Hyperinsulinemia and Urinary Calcium Excretion in Calcium Stone Formers With Idiopathic Hypercalciuria

2013 ◽  
Vol 98 (6) ◽  
pp. 2589-2594 ◽  
Author(s):  
Vivienne Yoon ◽  
Beverley Adams-Huet ◽  
Khashayar Sakhaee ◽  
Naim M. Maalouf
Keyword(s):  
Urinary Calcium ◽  
Urinary Calcium Excretion ◽  
Idiopathic Hypercalciuria ◽  
Calcium Excretion ◽  
Calcium Stone ◽  
Stone Formers

scholarly journals Role of 1,25-Dihydroxy Vitamin D3and Parathyroid Hormone in Urinary Calcium Excretion in Calcium Stone Formers

2014 ◽  
Vol 55 (5) ◽  
pp. 1326 ◽  
Author(s):  
Won Tae Kim ◽  
Yong-June Kim ◽  
Seok Joong Yun ◽  
Kyung-Sub Shin ◽  
Young Deuk Choi ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Urinary Calcium ◽  
Urinary Calcium Excretion ◽  
Calcium Excretion ◽  
Calcium Stone ◽  
Stone Formers

Effects of Eicosapentaenoic Acid on Urinary Calcium Excretion in Calcium Stone Formers

2001 ◽  
Vol 39 (5) ◽  
pp. 580-585 ◽  
Author(s):  
Takahiro Yasui ◽  
Hajime Tanaka ◽  
Keiji Fujita ◽  
Masanori Iguchi ◽  
Kenjiro Kohri
Keyword(s):  
Eicosapentaenoic Acid ◽  
Urinary Calcium ◽  
Urinary Calcium Excretion ◽  
Calcium Excretion ◽  
Calcium Stone ◽  
Stone Formers

Evidence that postprandial reduction of renal calcium reabsorption mediates hypercalciuria of patients with calcium nephrolithiasis

2007 ◽  
Vol 292 (1) ◽  
pp. F66-F75 ◽  
Author(s):  
Elaine M. Worcester ◽  
Daniel L. Gillen ◽  
Andrew P. Evan ◽  
Joan H. Parks ◽  
Katrina Wright ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Serum Magnesium ◽  
Normal Subjects ◽  
Urinary Calcium ◽  
Idiopathic Hypercalciuria ◽  
Calcium Excretion ◽  
Stone Formers ◽  
Calcium Reabsorption ◽  
Renal Tubular ◽  
Filtered Load

Idiopathic hypercalciuria (IH) is common among calcium stone formers (IHSF). The increased urinary calcium arises from increased intestinal absorption of calcium, but it is unclear whether increased filtered load or decreased renal tubular reabsorption of calcium is the main mechanism for the increased renal excretion. To explore this question, 10 IHSF and 7 normal subjects (N) were studied for 1 day. Urine and blood samples were collected at 30- to 60-min intervals while subjects were fasting and after they ate three meals providing known amounts of calcium, phosphorus, sodium, protein, and calories. Fasting and fed, ultrafiltrable calcium levels, and filtered load of calcium did not differ between N and IHSF. Urine calcium rose with meals, and fractional reabsorption fell in all subjects, but the change was significantly higher in IHSF. The changes in calcium excretion were independent of sodium excretion. Serum parathyroid hormone levels did not differ between N and IHSF, and they could not account for the greater fall in calcium reabsorption in IHSF. Serum magnesium and phosphorus levels in IHSF were below N throughout the day, and tubule phosphate reabsorption was lower in IHSF than N after meals. The primary mechanism by which kidneys ferry absorbed calcium into the urine after meals is via reduced tubule calcium reabsorption, and IHSF differ from N in the magnitude of the response. Parathyroid hormone is not likely to be a sufficient explanation for this difference.

scholarly journals CALCIUM

2010 ◽  
Vol 17 (04) ◽  
pp. 698-701
Author(s):  
MUHAMMAD ISHAQ ◽  
ISRAR AHMED AKHUND ◽  
MOULA BUX LAGHARI ◽  
Muhammad Sabir
Keyword(s):  
Urinary Tract ◽  
Serum Calcium ◽  
Upper Urinary Tract ◽  
Urinary Calcium ◽  
Stone Disease ◽  
Urinary Calcium Excretion ◽  
Calcium Excretion ◽  
Stone Formers ◽  
Study Results ◽  
Urinary Tract Stone

Aims & Objectives: To evaluate the effects of Serum Calcium and Urinary Calcium excretion on upper urinary tract stone diseases in the Peshawar (a high stone incidence belt). Subjects & Methods: One hundred patients (age 20-60years) who were suffering severely from upper urinary tract stone disease were selected from LRH and Hayatabad Medical Complex Hospitals of Peshawar, same numbers of healthy controls from the same region were also selected for the study. Results: When results were summed up and testParameters were compared, it was seen that mean Serum Calcium in stone formers was greater than that of non-stone formers (P<0.001). Same pattern was also observed (P< 0.001) in both groups regarding mean urinary calcium excretion. Conclusions: We concluded that calcium is a definitive risk factor in upper urinary tract stone disease. However we suggest further work and research on wide scale population inorder to evaluate this relation. 

scholarly journals Renal Tubular Impairment in Children with Idiopathic Hypercalciuria

2006 ◽  
Vol 49 (2) ◽  
pp. 109-111 ◽  
Author(s):  
Sylva Skálová ◽  
Štěpán Kutílek
Keyword(s):  
Reference Data ◽  
Urinary Calcium ◽  
Urinary Calcium Excretion ◽  
Idiopathic Hypercalciuria ◽  
Tubular Damage ◽  
Calcium Excretion ◽  
Spot Urine ◽  
Z Scores ◽  
Proximal Tubular ◽  
Renal Tubular

Idiopathic hypercalciuria (IH) is defined as hypercalciuria that persists after correction of dietary inbalances and has no detectable cause. The excretion of urinary N-acetyl-beta-D-glucosaminidase (U-NAG), a marker of proximal tubular damage, has been previously reported as either increased or normal in children with IH. We evaluated U-NAG in 20 children (13 boys and 7 girls, mean age 10.3 years ± 5.7 SD) with IH (urinary calcium excretion above 0.1 mmol/kg/24 hours, with no detectable cause) and with otherwise normal renal function tests. Ultrasound examination revealed urolithiasis (n = 4) and nephrocalcinosis (n = 1). The U-NAG values were evaluated in the spot urine collected from the second morning void and calculated as the urinary NAG/creatinine ratio (U-NAG/Cr) and expressed in nkat/mmol. The 24-hour urinary calcium excretion (U-Ca/24h) was assessed in a urinary sample from 24-hour collected urine and calculated in mmol/kg. The obtained results of U-Ca/24h and U-NAG/Cr were expressed as Z-scores. When compared to the reference data, the U-Ca/24h and U-NAG/Cr were significantly higher (p=0.0004 and p=0.006, respectively). There was no correlation between the U-NAG/Cr and U-Ca/24h (r = 0.18, p = 0.20). The U-NAG/Cr values were significantly higher in the 5 patients with urolithiasis/nephrocalcinosis, whether compared to the rest of the group (p=0.02), or to the reference data (p=0.01). The U-NAG/Cr activity was higher in 15 children without urolithiasis/nephrocalcinosis when compared to reference data (p < 0.01). There was no difference in U-Ca/24h between the children with and without urolithiasis/nephrocalcinosis (p = 0.58). These findings suggest that tubular impairment, as reflected by U-NAG/Cr, might occur in children with IH, especially in patients with urolithiasis/nephrocalcinosis. There doesn’t seem to be a direct relationship between the U-NAG/Cr activity and the degree of calcium leakage.

scholarly journals Unprocessed bran and its effect on urinary calcium excretion in idiopathic hypercalciuria.

BMJ ◽  
1980 ◽  
Vol 281 (6237) ◽  
pp. 426-426 ◽  
Author(s):  
P J Shah ◽  
N A Green ◽  
G Williams
Keyword(s):  
Urinary Calcium ◽  
Urinary Calcium Excretion ◽  
Idiopathic Hypercalciuria ◽  
Calcium Excretion

Indomethacin Lowers Urinary Calcium Excretion in Normal Volunteers and Normocalciuric Stone-Formers

Urolithiasis ◽  
1981 ◽  
pp. 723-725
Author(s):  
W. C. Carter ◽  
P. V. Halushka ◽  
D. Jones ◽  
B. Roof ◽  
S. N. Rous ◽  
...  
Keyword(s):  
Urinary Calcium ◽  
Urinary Calcium Excretion ◽  
Calcium Excretion ◽  
Normal Volunteers ◽  
Stone Formers
Sign in / Sign up

Export Citation Format

Share Document