Long term follow-up of transsphenoidal surgery for the treatment of Cushing's disease in childhood.

1995 ◽  
Vol 80 (8) ◽  
pp. 2475-2479 ◽  
Author(s):  
M C Leinung ◽  
L A Kane ◽  
B W Scheithauer ◽  
P C Carpenter ◽  
E R Laws ◽  
...  
Keyword(s):  
Cushing’S Disease ◽  
Transsphenoidal Surgery ◽  
Cushing's Disease ◽  
Long Term Follow Up

Results of repeated transsphenoidal surgery in Cushing's disease. Long-term follow-up

2014 ◽  
Vol 61 (4) ◽  
pp. 176-183 ◽  
Author(s):  
Pablo Valderrábano ◽  
Javier Aller ◽  
Leopoldo García-Valdecasas ◽  
José García-Uría ◽  
Laura Martín ◽  
...  
Keyword(s):  
Cushing’S Disease ◽  
Transsphenoidal Surgery ◽  
Cushing's Disease ◽  
Long Term Follow Up

scholarly journals Usefulness of desmopressin testing to predict relapse during long-term follow-up in patients in remission from Cushing’s disease

2017 ◽  
Vol 6 (8) ◽  
pp. 791-799 ◽  
Author(s):  
Alberto Giacinto Ambrogio ◽  
Massimiliano Andrioli ◽  
Martina De Martin ◽  
Francesco Cavagnini ◽  
Francesca Pecori Giraldi
Keyword(s):  
Cushing’S Disease ◽  
Transsphenoidal Surgery ◽  
Response Pattern ◽  
Disease Recurrence ◽  
Cushing's Disease ◽  
Close Monitoring ◽  
Long Term Follow Up ◽  
Over Time

Recurrence of Cushing’s disease after successful transsphenoidal surgery occurs in some 30% of the patients and the response to desmopressin shortly after surgery has been proposed as a marker for disease recurrence. The aim of the present study was to evaluate the response to desmopressin over time after surgery. We tested 56 patients with Cushing’s disease in remission after transsphenoidal surgery with desmopressin for up to 20 years after surgery. The ACTH and cortisol response to desmopressin over time was evaluated in patients on long-term remission or undergoing relapse; an increase by at least 27 pg/mL in ACTH levels identified responders. The vast majority of patients who underwent successful adenomectomy failed to respond to desmopressin after surgery and this response pattern was maintained over time in patients on long-term remission. Conversely, a response to desmopressin reappeared in patients who subsequently developed a recurrence of Cushing’s disease, even years prior to frank hypercortisolism. It appears therefore that a change in the response pattern to desmopressin proves predictive of recurrence of Cushing’s disease and may indicate which patients require close monitoring.

Results of repeated transsphenoidal surgery in Cushing's disease. Long-term follow-up

2014 ◽  
Vol 61 (4) ◽  
pp. 176-183
Author(s):  
Pablo Valderrábano ◽  
Javier Aller ◽  
Leopoldo García-Valdecasas ◽  
José García-Uría ◽  
Laura Martín ◽  
...  
Keyword(s):  
Cushing’S Disease ◽  
Transsphenoidal Surgery ◽  
Cushing's Disease ◽  
Long Term Follow Up

Long-term follow-up results of transsphenoidal surgery for Cushing’s disease in a single centre using strict criteria for remission

2002 ◽  
Vol 56 (4) ◽  
pp. 541-551 ◽  
Author(s):  
D. A. Rees ◽  
F. W. F. Hanna ◽  
J. S. Davies ◽  
R. G. Mills ◽  
J. Vafidis ◽  
...  
Keyword(s):  
Cushing’S Disease ◽  
Transsphenoidal Surgery ◽  
Cushing's Disease ◽  
Single Centre ◽  
Long Term Follow Up

Endocrinological long-term follow-up study of patients bilaterally adrenalectomized for Cushing's disease

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S107-S108
Author(s):  
A. EDELMANN ◽  
L. RADBRUCH ◽  
L. NOCKE-FINCK
Keyword(s):  
Cushing’S Disease ◽  
Cushing's Disease ◽  
Follow Up Study ◽  
Long Term Follow Up

Long Term Follow-Up of Patients with Cushing's Disease Treated by Interstitial Irradiation

1987 ◽  
Vol 65 (3) ◽  
pp. 441-447 ◽  
Author(s):  
LAURENCE M. SANDLER ◽  
NICHOLAS T. RICHARDS ◽  
DENIS H. CARR ◽  
KEITH MASHITER ◽  
GRAHAM F. JOPLIN
Keyword(s):  
Cushing’S Disease ◽  
Cushing's Disease ◽  
Interstitial Irradiation ◽  
Long Term Follow Up

MEGAVOLTAGE PITUITARY IRRADIATION IN THE MANAGEMENT OF CUSHING'S DISEASE AND NELSON'S SYNDROME: LONG-TERM FOLLOW-UP

1989 ◽  
Vol 31 (3) ◽  
pp. 309-323 ◽  
Author(s):  
T. A. HOWLETT ◽  
P. N. PLOWMAN ◽  
J. A. H. WASS ◽  
L. H. REES ◽  
A. E. JONES ◽  
...  
Keyword(s):  
Cushing’S Disease ◽  
Cushing's Disease ◽  
Nelson’S Syndrome ◽  
Nelson's Syndrome ◽  
Long Term Follow Up ◽  
Pituitary Irradiation
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