Glucose Rapidly and Reversibly Decreases INS-1 Cell Insulin Gene Transcription via Decrements in STF-1 and C1 Activator Transcription Factor Activity

Molecular Endocrinology ◽

10.1210/mend.12.2.0066 ◽

1998 ◽

Vol 12 (2) ◽

pp. 207-219 ◽

Author(s):

L. Karl Olson ◽

Jin Qian ◽

Vincent Poitout

Keyword(s):

Transcription Factor ◽

Gene Transcription ◽

Insulin Gene ◽

Transcription Factor Activity ◽

Factor Activity ◽

Insulin Gene Transcription

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The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression.

Molecular Endocrinology ◽

10.1210/mend.9.9.7491105 ◽

1995 ◽

Vol 9 (9) ◽

pp. 1127-1134 ◽

Author(s):

A Sharma ◽

L K Olson ◽

R P Robertson ◽

R Stein

Keyword(s):

Transcription Factor ◽

Gene Transcription ◽

High Glucose ◽

Glucose Concentration ◽

Insulin Gene ◽

High Glucose Concentration ◽

Factor Expression ◽

Transcription Factor Expression ◽

Insulin Gene Transcription

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Corrections: Reduction of Insulin Gene Transcription in HIT-T15 Cells Chronically Exposed to a Supraphysiologic Glucose Concentration is Associated With Loss of STF-1 Transcription Factor Expression

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.24.11322d ◽

1995 ◽

Vol 92 (24) ◽

pp. 11322d-11322

Author(s):

L. K. Olson

Keyword(s):

Transcription Factor ◽

Gene Transcription ◽

Glucose Concentration ◽

Insulin Gene ◽

Factor Expression ◽

Transcription Factor Expression ◽

Insulin Gene Transcription

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Evaluation of pancreatic .BETA. cell function in glucose toxicity model. Importance of insulin gene transcription factor PDX-1(IPF1) functional depression.

Proceedings of The Japanese Society of Animal Models for Human Diseases ◽

10.1538/expanim1992.13.79 ◽

1997 ◽

Vol 13 ◽

pp. 79-85

Author(s):

Yoshitaka KAJIMOTO ◽

Ryuzo KAWAMORI

Keyword(s):

Transcription Factor ◽

Beta Cell ◽

Gene Transcription ◽

Beta Cell Function ◽

Cell Function ◽

Pancreatic Beta Cell ◽

Insulin Gene ◽

Glucose Toxicity ◽

Pancreatic Beta Cell Function ◽

Insulin Gene Transcription

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The Cyclic AMP Response Element Modulator Family Regulates the Insulin Gene Transcription by Interacting with Transcription Factor IID

Journal of Biological Chemistry ◽

10.1074/jbc.274.30.21095 ◽

1999 ◽

Vol 274 (30) ◽

pp. 21095-21103 ◽

Author(s):

Akari Inada ◽

Yoshimichi Someya ◽

Yuichiro Yamada ◽

Yu Ihara ◽

Akira Kubota ◽

...

Keyword(s):

Transcription Factor ◽

Gene Transcription ◽

Insulin Gene ◽

Response Element ◽

Cyclic Amp Response Element ◽

Transcription Factor Iid ◽

Insulin Gene Transcription

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Activation of PPARδ up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate

Molecular and Cellular Biochemistry ◽

10.1007/s11010-012-1296-9 ◽

2012 ◽

Vol 366 (1-2) ◽

pp. 183-189 ◽

Author(s):

Mingming Cao ◽

Yang Long ◽

Yuzhen Tong ◽

Jun Wan ◽

Nanwei Tong

Keyword(s):

Transcription Factor ◽

Insulin Secretion ◽

Gene Transcription ◽

Insulin Gene ◽

Insulin Gene Transcription

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Identification of -cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.102168499 ◽

2002 ◽

Vol 99 (10) ◽

pp. 6737-6742 ◽

Author(s):

M. Olbrot ◽

J. Rud ◽

L. G. Moss ◽

A. Sharma

Keyword(s):

Transcription Factor ◽

Gene Transcription ◽

Insulin Gene ◽

Specific Insulin ◽

Insulin Gene Transcription

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Regulation of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus at concentrations that inhibit calcineurin activity and involving the transcription factor CREB

Naunyn-Schmiedeberg s Archives of Pharmacology ◽

10.1007/s00210-003-0694-7 ◽

2003 ◽

Vol 367 (3) ◽

pp. 227-236 ◽

Author(s):

Elke Oetjen ◽

Daniela Grapentin ◽

Roland Blume ◽

Michael Seeger ◽

Doris Krause ◽

...

Keyword(s):

Transcription Factor ◽

Cyclosporin A ◽

Human Insulin ◽

Gene Transcription ◽

Immunosuppressive Drugs ◽

Insulin Gene ◽

Human Insulin Gene ◽

Calcineurin Activity ◽

Insulin Gene Transcription

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XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor

Molecular Endocrinology ◽

10.1210/me.8.6.806 ◽

1994 ◽

Vol 8 (6) ◽

pp. 806-816 ◽

Author(s):

M. Peshavaria

Keyword(s):

Transcription Factor ◽

Gene Transcription ◽

Insulin Gene ◽

Homeodomain Protein ◽

Insulin Gene Transcription

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XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor.

Molecular Endocrinology ◽

10.1210/mend.8.6.7935494 ◽

1994 ◽

Vol 8 (6) ◽

pp. 806-816

Author(s):

M Peshavaria ◽

L Gamer ◽

E Henderson ◽

G Teitelman ◽

C V Wright ◽

...

Keyword(s):

Transcription Factor ◽

Gene Transcription ◽

Insulin Gene ◽

Homeodomain Protein ◽

Insulin Gene Transcription

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Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.20.9127 ◽

1995 ◽

Vol 92 (20) ◽

pp. 9127-9131 ◽

Author(s):

L. K. Olson ◽

A. Sharma ◽

M. Peshavaria ◽

C. V. Wright ◽

H. C. Towle ◽

...

Keyword(s):

Transcription Factor ◽

Gene Transcription ◽

Glucose Concentration ◽

Insulin Gene ◽

Factor Expression ◽

Transcription Factor Expression ◽

Insulin Gene Transcription

Download Full-text