Fluvastatin, a New Inhibitor of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase, Resists Hydroxyl Radical Generation in the Rat Myocardium

Journal of Pharmacy and Pharmacology ◽

10.1211/0022357001774020 ◽

2000 ◽

Vol 52 (4) ◽

pp. 425-430 ◽

Author(s):

TOSHIO OBATA ◽

AKIO EBIHARA ◽

YASUMITSU YAMANAKA

Keyword(s):

Hydroxyl Radical ◽

Rat Myocardium ◽

Radical Generation ◽

Coenzyme A Reductase

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Protective effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on copper-induced hydroxyl radical generation in the rat heart

10.1016/j.tox.2006.03.006 ◽

2006 ◽

Vol 223 (3) ◽

pp. 175-180 ◽

Author(s):

Toshio Obata

Keyword(s):

Protective Effect ◽

Hydroxyl Radical ◽

Rat Heart ◽

Radical Generation ◽

Coenzyme A Reductase

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Effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on nitric oxide-induced hydroxyl radical generation in the rat heart

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ◽

10.1016/s0925-4439(00)00090-9 ◽

2001 ◽

Vol 1536 (1) ◽

pp. 55-63 ◽

Author(s):

Toshio Obata ◽

Akio Ebihara ◽

Yasumitsu Yamanaka

Keyword(s):

Nitric Oxide ◽

Hydroxyl Radical ◽

Rat Heart ◽

Radical Generation ◽

Coenzyme A Reductase

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Protective effect of fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on MPP+-induced hydroxyl radical in the rat striatum

Brain Research ◽

10.1016/s0006-8993(00)02011-4 ◽

2000 ◽

Vol 860 (1-2) ◽

pp. 166-169 ◽

Author(s):

Toshio Obata ◽

Yasumitsu Yamanaka

Keyword(s):

Protective Effect ◽

Hydroxyl Radical ◽

Rat Striatum ◽

Coenzyme A Reductase

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Phytic acid suppresses ischemia-induced hydroxyl radical generation in rat myocardium

European Journal of Pharmacology ◽

10.1016/j.ejphar.2015.12.045 ◽

2016 ◽

Vol 774 ◽

pp. 20-24 ◽

Author(s):

Toshio Obata ◽

Michiko Nakashima

Keyword(s):

Hydroxyl Radical ◽

Phytic Acid ◽

Rat Myocardium ◽

Radical Generation

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The protective effect of fluvastatin on hydroxyl radical generation by inhibiting low-density lipoprotein (LDL) oxidation in the rat myocardium

Microvascular Research ◽

10.1016/j.mvr.2008.08.005 ◽

2009 ◽

Vol 77 (2) ◽

pp. 163-165 ◽

Author(s):

Toshio Obata ◽

Hidetoshi Yonemoti ◽

Masahiro Aomine

Keyword(s):

Protective Effect ◽

Hydroxyl Radical ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Ldl Oxidation ◽

Low Density ◽

Rat Myocardium ◽

Radical Generation

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Protective Effect of Histidine on Hydroxyl Radical Generation Induced by Potassium-Depolarization in Rat Myocardium

The Japanese Journal of Pharmacology ◽

10.1254/jjp.80.217 ◽

1999 ◽

Vol 80 (3) ◽

pp. 217-222 ◽

Author(s):

Toshio Obata ◽

Masahiro Aomine ◽

Yasumitsu Yamanaka

Keyword(s):

Protective Effect ◽

Hydroxyl Radical ◽

Rat Myocardium ◽

Potassium Depolarization ◽

Radical Generation

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Prazosin attenuates hydroxyl radical generation in the rat myocardium

European Journal of Pharmacology ◽

10.1016/s0014-2999(99)00504-x ◽

1999 ◽

Vol 379 (2-3) ◽

pp. 161-166 ◽

Author(s):

Toshio Obata ◽

Yasumitsu Yamanaka

Keyword(s):

Hydroxyl Radical ◽

Rat Myocardium ◽

Radical Generation

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Faculty Opinions recommendation of Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme a reductase (HMGCR) in patients with statin-associated autoimmune myopathy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8135957.8539056 ◽

2011 ◽

Author(s):

Jiri Vencovsky ◽

Herman Mann

Keyword(s):

Autoimmune Myopathy ◽

Coenzyme A Reductase

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Simvastatin, an HMG–Coenzyme A Reductase Inhibitor, Improves Endothelial Function Within 1 Month

Circulation ◽

10.1161/01.cir.95.5.1126 ◽

1997 ◽

Vol 95 (5) ◽

pp. 1126-1131 ◽

Author(s):

Gerard O'Driscoll ◽

Danny Green ◽

Roger R. Taylor

Keyword(s):

Endothelial Function ◽

Reductase Inhibitor ◽

Coenzyme A Reductase

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Tamoxifen protect against hydroxyl radical generation induced by phenelzine in rat striatum

10.1016/j.tox.2006.01.023 ◽

2006 ◽

Vol 222 (1-2) ◽

pp. 46-52 ◽

Author(s):

Toshio Obata

Keyword(s):

Hydroxyl Radical ◽

Rat Striatum ◽

Radical Generation

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