Longitudinal study of fiber density and motor unit number estimate in patients with amyotrophic lateral sclerosis

Neurology ◽  
1997 ◽  
Vol 49 (2) ◽  
pp. 573-578 ◽  
Author(s):  
E. C. Yuen ◽  
R. K. Olney
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Longitudinal Study ◽  
Motor Unit ◽  
Fiber Density ◽  
Motor Unit Number Estimate ◽  
Lateral Sclerosis

103. Longitudinal study of thenar motor unit number estimates in amyotrophic lateral sclerosis patients

2008 ◽  
Vol 119 (3) ◽  
pp. e58-e59
Author(s):  
X. Liu ◽  
J. Zhang ◽  
J. Zheng ◽  
S. Zhang ◽  
Y. Xu ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Longitudinal Study ◽  
Motor Unit ◽  
Lateral Sclerosis

scholarly journals Motor Unit Number Estimation in Neuromuscular Disease

2008 ◽  
Vol 35 (2) ◽  
pp. 153-159 ◽  
Author(s):  
Omid Rashidipour ◽  
K. Ming Chan
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Motor Unit ◽  
Neuromuscular Disease ◽  
Muscular Atrophy ◽  
Neuromuscular Diseases ◽  
Neuronal Loss ◽  
Response To Treatment ◽  
Motor Unit Number Estimation ◽  
Electrophysiological Method ◽  
Lateral Sclerosis

Motor unit number estimation (MUNE) is an electrophysiological method designed to quantify motor unit loss in target muscles of interest. Most of the techniques are noninvasive and are therefore well suited for longitudinal monitoring. In this brief review, we describe the more commonly used techniques and their applications in amyotrophic lateral sclerosis, poliomyelitis, spinal muscular atrophy and hereditary sensorimotor neuropathies. Findings in some of these studies offer important pathophysiological insights. Since conventional electrophysiologic methods are not sensible measures of motor neuronal loss, MUNE could play a potentially important role in the diagnosis, monitoring of disease progression and response to treatment in neuromuscular diseases in which motor unit loss is a major feature.

Motor unit hyperexcitability in amyotrophic lateral sclerosis vs amino acids acting as neurotransmitters

2002 ◽  
Vol 106 (1) ◽  
pp. 34-38 ◽  
Author(s):  
A. Kostera-Pruszczyk ◽  
I. Niebroj-Dobosz ◽  
B. Emeryk-Szajewska ◽  
A. Karwańska ◽  
K. Rowińska-Marcińska
Keyword(s):  
Amino Acids ◽  
Amyotrophic Lateral Sclerosis ◽  
Motor Unit ◽  
Lateral Sclerosis
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