A Familial Coincidence of Pseudotumor Cerebri and Communicating Hydrocephalus

Neurosurgery ◽  
1991 ◽  
Vol 28 (5) ◽  
pp. 727-729 ◽  
Author(s):  
Ian Johnston ◽  
Michael K. Morgan
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
The Other ◽  
Communicating Hydrocephalus ◽  
Fluid Absorption ◽  
Cerebrospinal Fluid Absorption ◽  
History Of

Abstract A family in which the mother and two of four daughters had a diagnosis of pseudotumor cerebri and one son developed communicating hydrocephalus is described. The other two daughters both have a long history of headaches but no signs of intracranial hypertension. The argument is advanced that there exists a defect of cerebrospinal fluid absorption common to pseudotumor cerebri and communicating hydrocephalus.

An Alternative Pathway of Cerebrospinal Fluid Absorption in Communicating Hydrocephalus

Radiology ◽  
1974 ◽  
Vol 111 (1) ◽  
pp. 143-146 ◽  
Author(s):  
A. Everette James ◽  
Ernst-Peter Strecker ◽  
Ed Sperber ◽  
William J. Flor ◽  
Timothy Merz ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Alternative Pathway ◽  
Communicating Hydrocephalus ◽  
Fluid Absorption ◽  
Cerebrospinal Fluid Absorption

scholarly journals Familial Benign Intracranial Hypertension and Depression

1982 ◽  
Vol 9 (1) ◽  
pp. 45-47 ◽  
Author(s):  
C. Edward Coffey ◽  
Donald R. Ross ◽  
E. Wayne Massey ◽  
C. Warren Olanow
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Benign Intracranial Hypertension ◽  
Fluid Absorption ◽  
Major Depressive ◽  
Cerebrospinal Fluid Absorption ◽  
Related Individuals ◽  
Pituitary Adrenal Axis

SUMMARY:Two sisters developed benign intracranial hypertension (BIH) two weeks following the resolution of a major depressive episode. The association of BIH and a major affective disorder in genetically related individuals has not been previously reported to our knowledge. Both conditions are associated with disturbances in the hypothalamic-pituitary-adrenal axis. Falling corticosteroid levels in a resolving depression may result in impaired cerebrospinal fluid absorption and subsequent BIH.

Diverse Clinical Applications of Percutaneous Lumboperitoneal Shunts

Neurosurgery ◽  
1981 ◽  
Vol 8 (1) ◽  
pp. 39-42 ◽  
Author(s):  
H. E. James ◽  
P. A. Tibbs
Keyword(s):  
Cerebrospinal Fluid ◽  
Wound Dehiscence ◽  
Pseudotumor Cerebri ◽  
Shunt Infection ◽  
Communicating Hydrocephalus ◽  
Lumbar Region ◽  
Csf Fistula ◽  
Shunt Removal ◽  
Shunt Migration ◽  
Shunt Obstruction

Abstract A population of 28 patients underwent the percutaneous placement of a shunt in the lumbar region with a single tube, the other end of which was placed in the peritoneal cavity by laparotomy. The clinical indications for the procedure were: communicating hydrocephalus (16 patients), pseudotumor cerebri (3 patients), cranial cerebrospinal fluid fistula (4 patients), and a bulging postcraniotomy site (2 patients). An additional 3 patients were treated by lumbar subcutaneousperitoneal shunt for a cerebrospinal fluid (CSF)-subcutaneous fistula after the removal of a leptomyelolipoma. The mean time of follow-up was 18.8 ± 7.8 months. All patients with pseudotumor cerebri and subcutaneous lumbar CSF fistula and all but 1 of the patients with a cranial CSF fistula improved without further therapy. Twelve of the 16 patients with communicating hydrocephalus improved and did not require other shunt procedures. There was one shunt infection, one wound dehiscence that led to shunt removal, and one shunt migration into the spinal canal. Shunt obstruction that led to revision of the shunt occurred on three occasions in 2 patients. The shunt functioned in only 1 of 4 infants under 4 months of age.

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