scholarly journals Spalt transcription factors are required for R3/R4 specification and establishment of planar cell polarity in the Drosophila eye

Development ◽  
2004 ◽  
Vol 131 (22) ◽  
pp. 5695-5702 ◽  
Author(s):  
P. M. Domingos



2015 ◽  
Author(s):  
Liqun Yuan ◽  
Shu Hu ◽  
Zeynep Okray ◽  
Xi Ren ◽  
Natalie De Geest ◽  
...  

AbstractThe Neurogenin (Ngn) transcription factors control early neurogenesis and neurite outgrowth in mammalian cortex. In contrast to their proneural activity, their function in neurite growth is poorly understood. Drosophila has a single predicted Ngn homologue called Tap, whose function is completely unknown. Here we show that Tap is not a proneural protein in Drosophila but is required for proper axonal growth and guidance of neurons of the mushroom body (MB), a neuropile required for associative learning and memory. Genetic and expression analyses suggest that Tap inhibits excessive axonal growth by fine regulation of the levels of the Wnt signaling adaptor protein, Dishevelled.SummaryThe Drosophila Neurogenin homologue, Target of Pox neuro (Tap), prevents axonal overgrowth by regulating the Wnt Planar Cell Polarity pathway adaptor protein Dishevelled.



Cell ◽  
2005 ◽  
Vol 121 (4) ◽  
pp. 497-499 ◽  
Author(s):  
François Schweisguth


2019 ◽  
Vol 160 ◽  
pp. 103583
Author(s):  
Pedro M. Domingos ◽  
Andreas Jenny ◽  
Keon F. Combie ◽  
David del Alamo ◽  
Marek Mlodzik ◽  
...  


Cell ◽  
2005 ◽  
Vol 121 (4) ◽  
pp. 621-631 ◽  
Author(s):  
Alexandre Djiane ◽  
Shaul Yogev ◽  
Marek Mlodzik


2008 ◽  
Vol 316 (1) ◽  
pp. 110-123 ◽  
Author(s):  
Ursula Weber ◽  
Csilla Pataki ◽  
Jozsef Mihaly ◽  
Marek Mlodzik


Sign in / Sign up

Export Citation Format

Share Document