A new device for the treatment of female stress urinary incontinence

Author(s):  
L van Veggel ◽  
M Morrell ◽  
C Harris ◽  
M Dormans-Linssen

Treatment for stress urinary incontinence (SUI) comprises a broad range of possible interventions. Non-surgical options include absorbent pads, vaginal weights and cones, biofeedback and minimally invasive techniques such as urethral bulking agents (UBAs). Surgical interventions range in complexity from sling surgery and suspension techniques to more major surgeries such as burch colposuspension. Each option has its challenges and limitations. This paper will focus on UBAs, which are implantable materials whose purpose is to augment urethral tissue function and restore continence. The characteristics required of such materials, and the challenges to be overcome when incorporating them in a successful product design, will be described and discussed. Particular attention will be given to the latest developments in the administration of polydimethylsiloxane elastomer UBA.

2019 ◽  
Vol 26 (4) ◽  
pp. 84-93
Author(s):  
V. F. Bezhenar ◽  
B. V. Arakelyan ◽  
V. A. Krutova ◽  
O. V. Tarabanova ◽  
A. A. Khachetsukova ◽  
...  

Aim. The article presents information on modern urethral bulking agents used in the treatment of female stress urinary incontinence (SUI).Materials and methods. The authors reviewed the current scientifi c literature on the topic (original articles, monographs, meta-analyses), whose relevance lies in the increasing interest of both clinicians and patients in the minimally invasive treatment of SUI.Results. On the basis of available information on the use of urethral bulking agents, regulatory bodies prohibited the use of substances that did not meet the requirements of safety and effi cacy. Substances approved for clinical use are safe and show considerable effect, which makes them a suitable alternative to the surgical treatment of SUI.Conclusions. This kind of treatment is characterised by a low rate of serious complications and a suffi ciently high level of patients’ satisfaction with the results, despite its lower objective cure rate. Further research in this area involves a search for the “ideal” urethral bulking agent, as well as the use of cell technologies.


2017 ◽  
Vol 11 (6S2) ◽  
pp. 152 ◽  
Author(s):  
Adiel Mamut ◽  
Kevin V. Carlson

Urethral bulking aims to improve urethral mucosal coaptation, and thus outlet resistance, in an effort to limit stress-induced leakage. While efforts have been made to employ bulking agents to treat stress urinary incontinence (SUI) for more than 100 years, we remain wanting for the perfect injectable. Regardless of the agent studied, efficacy is modest at best, repeat injections are the norm, and longterm followup is conspicuously lacking. This treatment, however, fills an important need in our armamentarium against SUI, serving those patients who are not candidates for more invasive interventions and those with multiple prior failed surgeries. This review offers a contemporary discussion on the role of periurethral bulking therapy in Canada, along with practical aspects of its application.


2020 ◽  
pp. 761-822
Author(s):  
Suzanne Biers ◽  
Noel Armenakas ◽  
Alastair Lamb ◽  
Stephen Mark ◽  
John Reynard ◽  
...  

This chapter covers female stress urinary incontinence and its management, including assessment, non-operative management, urethral bulking agents, artificial urinary sphincters, and different types of sling. It also describes modes of management for male stress urinary incontinence, pelvic organ prolapse, female urethral diverticulum, and the repair of vesicovaginal fistula.


2020 ◽  
Vol Volume 12 ◽  
pp. 495-501
Author(s):  
Manami Kinjo ◽  
Kazuki Masuda ◽  
Yu Nakamura ◽  
Satoru Taguchi ◽  
Mitsuhiro Tambo ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document