The Juliá-Colonna Type Asymmetric Epoxidation Reaction Catalyzed by Soluble Oligo-L-leucines Containing an α-Aminoisobutyric Acid Residue: Importance of Helical Structure of the Catalyst on Asymmetric Induction

2000 ◽  
Vol 29 (4) ◽  
pp. 366-367 ◽  
Author(s):  
Ryukichi Takagi ◽  
Akiko Shiraki ◽  
Toshiki Manabe ◽  
Satoshi Kojima ◽  
Katsuo Ohkata
Keyword(s):  
Helical Structure ◽  
Asymmetric Induction ◽  
Asymmetric Epoxidation ◽  
Aminoisobutyric Acid ◽  
Epoxidation Reaction

Facile synthesis of the enantiomers of frontalin

1984 ◽  
Vol 62 (11) ◽  
pp. 2148-2154 ◽  
Author(s):  
B. D. Johnston ◽  
A. C. Oehlschlager
Keyword(s):  
Asymmetric Epoxidation ◽  
Facile Synthesis ◽  
Epoxidation Reaction ◽  
Synthetic Sequence ◽  
Sharpless Asymmetric Epoxidation

S-(−)- and R-(+)-frontalin (1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane) were prepared from (E)-2-methyl-2,6-heptadiene-1-ol utilizing the Sharpless asymmetric epoxidation reaction to induce chirality. The six-step synthetic sequence proceeded in approximately 50% overall yield and was found to be suitable for the preparation of multi-gram quantities of either enantiomer with ≥ 90% ee.

Asymmetric epoxidation of alkenes catalyzed by novel chiral porphyrin metal complexes

2016 ◽  
Vol 20 (06) ◽  
pp. 730-737 ◽  
Author(s):  
Pachiannan Sakthipriya ◽  
Nallamuthu Ananthi
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Asymmetric Epoxidation ◽  
Excellent Yield ◽  
Chiral Epoxides ◽  
Epoxidation Reaction ◽  
Epoxidation Of Alkenes

Novel chiral porphyrin ligands were synthesized from four different chiral aldehydes. In situ transition metal complexes of these novel chiral porphyrin ligands were found to catalyze asymmetric epoxidation reaction of styrene possessing various substituents. The chiral epoxides were formed in excellent yield and ee.

Development of the Juliá−Colonna Asymmetric Epoxidation Reaction:  Part 1. Preparation and Activation of the Polyleucine Catalyst

2003 ◽  
Vol 7 (4) ◽  
pp. 509-513 ◽  
Author(s):  
Sylvia Baars ◽  
Karl-Heinz Drauz ◽  
Hans-Peter Krimmer ◽  
Stanley M. Roberts ◽  
Jörg Sander ◽  
...  
Keyword(s):  
Asymmetric Epoxidation ◽  
Epoxidation Reaction
Sign in / Sign up

Export Citation Format

Share Document