scholarly journals Interaction of DNA Minor Groove Binder Hoechst 33258 with Bovine Serum Albumin

2009 ◽  
Vol 57 (5) ◽  
pp. 481-486 ◽  
Author(s):  
Himanshu Ojha ◽  
Bhaskar Mohan Murari ◽  
Sneh Anand ◽  
Mohd Imtaiyaz Hassan ◽  
Faizan Ahmad ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Minor Groove ◽  
Minor Groove Binder ◽  
Hoechst 33258 ◽  
Dna Minor Groove ◽  
Dna Minor Groove Binder

DNA Binding Compounds. VII. Synthesis, Characterization and DNA Binding Capacity of 1,2-Dicarba-closo-dodecaborane Bibenzimidazoles Related to the DNA Minor Groove Binder Hoechst 33258

1999 ◽  
Vol 52 (4) ◽  
pp. 291 ◽  
Author(s):  
Stuart A. Bateman ◽  
David P. Kelly ◽  
Jonathan M. White ◽  
Roger F. Martin
Keyword(s):  
Dna Binding ◽  
Binding Capacity ◽  
Minor Groove ◽  
Minor Groove Binder ◽  
Hoechst 33258 ◽  
Binding Studies ◽  
Dna Minor Groove ◽  
Dna Binding Studies ◽  
Carborane Ligand ◽  
Dna Minor Groove Binder

A series of bibenzimidazole derivatives based on the known DNA minor groove binder Hoechst 33258 have been prepared to include a 1,2-dicarba-closo-dodecaborane cage for potential use in boron neutron capture therapy (BNCT). The carborane derivatives (5){(7) were chosen to reduce the steric inhibition of minor groove DNA binding displayed by the previously prepared carborane ligand (4). The synthesis and preliminary DNA binding studies of these bibenzimidazole derivatives are presented herein.

ChemInform Abstract: Hoechst 33258, a Specific DNA Minor Groove Binder

ChemInform ◽  
2010 ◽  
Vol 28 (18) ◽  
pp. no-no
Author(s):  
S. FRAU ◽  
J. BERNADOU ◽  
B. MEUNIER
Keyword(s):  
Minor Groove ◽  
Minor Groove Binder ◽  
Hoechst 33258 ◽  
Dna Minor Groove ◽  
Dna Minor Groove Binder

DNA Binding Compounds. V. Synthesis and Characterization of Boron Containing Bibenzimidazoles Related to the DNA Minor Groove Binder, Hoechst-33258

1994 ◽  
Vol 47 (2) ◽  
pp. 247 ◽  
Author(s):  
DP Kelly ◽  
SA Bateman ◽  
RF Martin ◽  
ME Reum ◽  
M Rose ◽  
...  
Keyword(s):  
Neutron Capture ◽  
Minor Groove ◽  
Synthesis And Characterization ◽  
Neutron Capture Therapy ◽  
Minor Groove Binder ◽  
Hoechst 33258 ◽  
Dna Minor Groove ◽  
Boron Neutron Capture ◽  
Dna Minor Groove Binder

The synthesis and characterization of four novel boron-containing bibenzimidazoles related to the DNA minor groove binder Hoechst 33258 are reported. Such compounds, particularly their 1�B-enriched forms, have potential as agents for boron neutron capture therapy which is used in the treatment of cancers.

scholarly journals Trabectedin – the DNA minor groove binder

2015 ◽  
Vol 2 (2) ◽  
pp. 41
Author(s):  
G. A. Belitsky ◽  
K. I. Kirsanov ◽  
E. A. Lesovaya ◽  
M. G. Yakubovskaya
Keyword(s):  
Minor Groove ◽  
Minor Groove Binder ◽  
Dna Minor Groove ◽  
Dna Minor Groove Binder
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