scholarly journals Adenosine kinase deficiency with neurodevelopemental delay and recurrent hepatic dysfunction: A case report

2016 ◽  
Vol 03 (01) ◽  
Author(s):  
Shakiba M ◽  
Mahjoub F ◽  
Fazilaty H ◽  
Rezagholizadeh F ◽  
Shakiba A ◽  
...  

Author(s):  
Midori Awazu ◽  
Tetsuya Tanaka ◽  
Seiji Sato ◽  
Makoto Anzo ◽  
Masataka Higuchi ◽  
...  

Author(s):  
C. Prarthana Saraswathi ◽  
J. Anu Rita ◽  
S. Nambi

Valproate is a commonly used mood stabilizer. One of the important and rare side effects of valproate is hyperammonemia leading to delirium and hepatic encephalopathy. Valproate-induced delirium is commonly mistaken for worsening of manic symptoms or psychosis. We hereby report a case of bipolar affective disorder who was on a therapeutic dose of valproate monotherapy developed altered mental status where we found elevated levels of plasma ammonia which decreased after the discontinuation of valproate and with normal levels of serum valproate, LFT’s, EEG and imagings. This case report emphasises on the need to consider plasma ammonia levels in patients with altered mental status receiving valproate in addition to other investigations.


2006 ◽  
Vol 51 (3) ◽  
pp. 359 ◽  
Author(s):  
Yong Son ◽  
Yong Kwan Cheong ◽  
Dea Jung Kim

PEDIATRICS ◽  
1987 ◽  
Vol 79 (2) ◽  
pp. 281-282
Author(s):  
DAVID J. BAILEY ◽  
JOEL M. ANDRES

N-acetylcysteine (NAC) is a mucolytic agent (Mucomyst, Mead-Johnson) that is often used for the treatment of meconium ileus equivalent, a complication of cystic fibrosis.1-3 No serious adverse reactions to nonparenterally administered NAC have been observed, and there have been no reports of significant hepatotoxicity. We describe a patient in whom severe hepatic dysfunction occurred on two occasions after the administration of NAC for the treatment of meconium ileus equivalent. CASE REPORT A 3-year-old, 12.5-kg, white boy with cystic fibrosis was admitted for treatment of a fractured left femur. His medications included theophylline, metaproterenol, cefaclor, nebulized isoethanine, and pancreatic enzyme replacement with meals.


2006 ◽  
Vol 51 (3) ◽  
pp. 363
Author(s):  
Hyo Seok Kang ◽  
Jong Oh Lim ◽  
So Jin Park ◽  
Soo Kyeong Choi ◽  
Hae Jin Park ◽  
...  

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