The Fisher information matrix on a type II doubly censored sample from a Dagum distribution

2013 ◽  
Vol 7 ◽  
pp. 3715-3729 ◽  
Author(s):  
Filippo Domma ◽  
Sabrina Giordano ◽  
Mariangela Zenga
Keyword(s):  
Fisher Information ◽  
Fisher Information Matrix ◽  
Information Matrix ◽  
Type Ii ◽  
Dagum Distribution ◽  
Doubly Censored ◽  
Censored Sample

scholarly journals Optimal design for population pk/pd models

2012 ◽  
Vol 51 (1) ◽  
pp. 115-130
Author(s):  
Sergei Leonov ◽  
Alexander Aliev
Keyword(s):  
Optimal Design ◽  
Fisher Information ◽  
Fisher Information Matrix ◽  
Information Matrix ◽  
Optimal Sampling ◽  
Design Algorithm ◽  
Sampling Schemes ◽  
Population Pk ◽  
Different Types

ABSTRACT We provide some details of the implementation of optimal design algorithm in the PkStaMp library which is intended for constructing optimal sampling schemes for pharmacokinetic (PK) and pharmacodynamic (PD) studies. We discuss different types of approximation of individual Fisher information matrix and describe a user-defined option of the library.

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