Development and Validation of RP- HPLC Method for Simultaneous Determination of Niacin (Extended Release) and Lovastatin in Oral Solid Dosage Form

2012 ◽  
Vol 28 (2) ◽  
pp. 887-893 ◽  
Author(s):  
G.S. DEVIKA ◽  
M. SUDHAKAR ◽  
J. VENKATESHWARA RAO
2010 ◽  
Vol 7 (3) ◽  
pp. 947-952 ◽  
Author(s):  
Rajesh Sharma ◽  
Ganesh Prasad Mishra ◽  
Subhash Chandra Chaturvedi

A simple, sensitive, precise, accurate, rapid and reproducible reverse phase high performance liquid chromatographic procedure is developed for simultaneous determination of rabeprazole sodium and itopride hydrochloride in solid dosage form. The mobile phase used was a combination of acetonitrile: buffer (35:65 v/v) and the pH was adjusted to 7.0 ± 0.1 by addition of triethylamine. The detection of the capsule dosage form was carried out at 266 nm and a flow rate employed was 1 mL/min. Linearity was obtained in the concentration range of 2 to 16 μg/mL of rabeprazole sodium and 5 to 55 μg/mL of itopride hydrochloride with a correlation coefficient of 0.9992 and 0.9996 respectively. The results of the analysis were validated statistically and recovery studies confirmed the accuracy of the proposed method.


2009 ◽  
Vol 8 (4) ◽  
pp. 184
Author(s):  
S. G. Vasantharaju ◽  
Mishra Akanksha ◽  
Arumugam Karthik ◽  
Musmade P. Prashant ◽  
Udupa Nayanabhirama ◽  
...  

2016 ◽  
Vol 03 (01) ◽  
pp. 14-22
Author(s):  
Prathap Boobalan ◽  
Srinivasa Rao Gorantla ◽  
Gobalakrishnan Pandurangan ◽  
Venkata Swathikrishna Kavuluru ◽  
Priyanka Vadthey

2010 ◽  
Vol 72 (4) ◽  
pp. 513 ◽  
Author(s):  
Manisha Puranik ◽  
DV Bhawsar ◽  
Prachi Rathi ◽  
PG Yeole

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