scholarly journals Simultanious Determination of Related Organic Impurities of Ibuprofen and Paracetamol in Combination Solid Dosage Form by Rp-hplc With Qbd Approach

2017 ◽  
Vol 33 (3) ◽  
pp. 1461-1468 ◽  
Author(s):  
Palakurthi Ashok Kumar ◽  
Dongala Thirupathi ◽  
Y Ravindra Kumar ◽  
Anireddy Jayashree
2009 ◽  
Vol 8 (4) ◽  
pp. 184
Author(s):  
S. G. Vasantharaju ◽  
Mishra Akanksha ◽  
Arumugam Karthik ◽  
Musmade P. Prashant ◽  
Udupa Nayanabhirama ◽  
...  

2010 ◽  
Vol 72 (4) ◽  
pp. 513 ◽  
Author(s):  
Manisha Puranik ◽  
DV Bhawsar ◽  
Prachi Rathi ◽  
PG Yeole

Author(s):  
Puranik Manisha ◽  
Shambharkar Samta ◽  
Nimbalkar Shantanu ◽  
Mahapatra Debarshi Kar

2010 ◽  
Vol 7 (3) ◽  
pp. 947-952 ◽  
Author(s):  
Rajesh Sharma ◽  
Ganesh Prasad Mishra ◽  
Subhash Chandra Chaturvedi

A simple, sensitive, precise, accurate, rapid and reproducible reverse phase high performance liquid chromatographic procedure is developed for simultaneous determination of rabeprazole sodium and itopride hydrochloride in solid dosage form. The mobile phase used was a combination of acetonitrile: buffer (35:65 v/v) and the pH was adjusted to 7.0 ± 0.1 by addition of triethylamine. The detection of the capsule dosage form was carried out at 266 nm and a flow rate employed was 1 mL/min. Linearity was obtained in the concentration range of 2 to 16 μg/mL of rabeprazole sodium and 5 to 55 μg/mL of itopride hydrochloride with a correlation coefficient of 0.9992 and 0.9996 respectively. The results of the analysis were validated statistically and recovery studies confirmed the accuracy of the proposed method.


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