Workfare’s persistent philosophical and legal issues: forced labour, reciprocity and a basic income guarantee

Author(s):  
Amir Paz-Fuchs

This chapter addresses four persistent legal and philosophical issues that imbue workfare, albeit usually not explicitly. First, forced labour is a relatively common charge against workfare. If workfare is tantamount to forced labour, it cannot be justified, legally or morally. But to what extent do we truly object to forcing people to work? Second, the chapter asks what is unique about requiring people to work? Third, we address reciprocity, probably the most persuasive, most common, and most controversial argument in justifying workfare. And finally, the chapter addresses Basic Income Guarantee, which is the mirror image of forced labour: If forced labour is the epitome of the ills of capitalism, basic income is the tool to save capitalism from itself. If forced labour is the charge, basic income is the (perceived) solution. But it also addresses the problems of conditionality. For if Basic Income is not only plausible, but morally justified, it offers a strong argument against conditioning benefits on work.

2020 ◽  
Vol 477 (15) ◽  
pp. 2921-2934
Author(s):  
Rodrigo D. Requião ◽  
Géssica C. Barros ◽  
Tatiana Domitrovic ◽  
Fernando L. Palhano

Protein segments with a high concentration of positively charged amino acid residues are often used in reporter constructs designed to activate ribosomal mRNA/protein decay pathways, such as those involving nonstop mRNA decay (NSD), no-go mRNA decay (NGD) and the ribosome quality control (RQC) complex. It has been proposed that the electrostatic interaction of the positively charged nascent peptide with the negatively charged ribosomal exit tunnel leads to translation arrest. When stalled long enough, the translation process is terminated with the degradation of the transcript and an incomplete protein. Although early experiments made a strong argument for this mechanism, other features associated with positively charged reporters, such as codon bias and mRNA and protein structure, have emerged as potent inducers of ribosome stalling. We carefully reviewed the published data on the protein and mRNA expression of artificial constructs with diverse compositions as assessed in different organisms. We concluded that, although polybasic sequences generally lead to lower translation efficiency, it appears that an aggravating factor, such as a nonoptimal codon composition, is necessary to cause translation termination events.


1975 ◽  
Vol 20 (6) ◽  
pp. 505-506
Author(s):  
HAROLD GRAFF
Keyword(s):  

1988 ◽  
Vol 33 (9) ◽  
pp. 833-833
Author(s):  
No authorship indicated
Keyword(s):  

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