This chapter argues that the parliamentary animal welfare campaign of the early nineteenth century, culminating in Martin’s Act (1822), was the heir to the radical movements of the 1790s. The literary representation of animals as feeling subjects, and the complex relationship between human and animal rights, both had profound effects on the anti-cruelty debate. Focusing on contributions by John Lawrence, an early exponent of legal rights for animals, Thomas Erskine, who introduced an unsuccessful Cruelty to Animals bill in 1809, and Margaret Cullen, who brought the debate about animals into the domestic novel, I show how they used and adapted radical political ideas in the service of animal welfare. The literature of animal subjectivity underpinned the anti-cruelty campaign and helped achieve legislation; but success depended on melding new attitudes with old hierarchies and turning away from the more radical implications of the reassessment of animal life.