Application of Oestrogen Receptor Ligand Binding Domain to the Generic Isolation of Oestrogens by Receptor Affinity Chromatography

2004 ◽  
Vol 59 (S1) ◽  
pp. S123-S130 ◽  
Author(s):  
M. F. Byford ◽  
M. J. Sauer
Keyword(s):  
Ligand Binding ◽  
Affinity Chromatography ◽  
Oestrogen Receptor ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand ◽  
Receptor Affinity

scholarly journals A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

1995 ◽  
Vol 23 (10) ◽  
pp. 1686-1690 ◽  
Author(s):  
T. D. Littlewood ◽  
D. C. Hancock ◽  
P. S. Danielian ◽  
M. G. Parker ◽  
G. I. Evan
Keyword(s):  
Ligand Binding ◽  
Oestrogen Receptor ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Heterologous Proteins ◽  
Receptor Ligand

Parabens bind directly to recombinant human oestrogen receptor ligand binding domain

2001 ◽  
Vol 29 (1) ◽  
pp. A41-A41
Author(s):  
M. F. Byford ◽  
J. R. Higman ◽  
P. D. Darbre ◽  
M. J. Sauer
Keyword(s):  
Ligand Binding ◽  
Oestrogen Receptor ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand

scholarly journals Structural plasticity in the oestrogen receptor ligand‐binding domain

EMBO Reports ◽  
2007 ◽  
Vol 8 (6) ◽  
pp. 563-568 ◽  
Author(s):  
Kendall W Nettles ◽  
John B Bruning ◽  
German Gil ◽  
Erin E O'Neill ◽  
Jason Nowak ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Oestrogen Receptor ◽  
Structural Plasticity ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand

Structure and mechanism of the oestrogen receptor

2003 ◽  
Vol 31 (1) ◽  
pp. 56-59 ◽  
Author(s):  
E.H. Kong ◽  
A.C.W. Pike ◽  
R.E. Hubbard
Keyword(s):  
Ligand Binding ◽  
Transcriptional Activation ◽  
Oestrogen Receptor ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Pharmacological Properties ◽  
Receptor Ligand ◽  
Structural Mechanisms

We have determined the structures of the oestrogen receptor ligand-binding domain in complex with a range of ligands and with fragments of co-regulator proteins. These structures provide insights into the structural mechanisms underlying the receptor's complex pharmacological properties and how the conformation of the receptor modulates its ability to recruit co-regulators that are necessary for transcriptional activation.

scholarly journals Structural plasticity in the oestrogen receptor ligand‐binding domain

EMBO Reports ◽  
2007 ◽  
Vol 8 (6) ◽  
pp. 610-610 ◽  
Author(s):  
Kendall W Nettles ◽  
John B Bruning ◽  
German Gil ◽  
Erin E O'Neill ◽  
Jason Nowak ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Oestrogen Receptor ◽  
Structural Plasticity ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand
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