LC-ESI-MS-MS Determination of Rat Plasma Protein Binding of Major Flavonoids of Flos Lonicerae Japonicae by Centrifugal Ultrafiltration

2010 ◽  
Vol 72 (1-2) ◽  
pp. 71-77 ◽  
Author(s):  
Yongdong Luo ◽  
Shuisheng Wu ◽  
Xiaoyan Li ◽  
Ping Li
Keyword(s):  
Protein Binding ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Rat Plasma ◽  
Esi Ms ◽  
Flos Lonicerae ◽  
Centrifugal Ultrafiltration ◽  
Flos Lonicerae Japonicae

Bioavailability, plasma protein binding and metabolic stability studies of a ALDH2 activator, alda-1, using a validated LC-ESI-MS/MS method in rat plasma

RSC Advances ◽  
2015 ◽  
Vol 5 (67) ◽  
pp. 54395-54402 ◽  
Author(s):  
Isha Taneja ◽  
Kanumuri Siva Rama Raju ◽  
Monika Mittal ◽  
Kapil Dev ◽  
Mohammad Faheem Khan ◽  
...  
Keyword(s):  
Protein Binding ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Rat Plasma ◽  
Metabolic Stability ◽  
Stability Studies ◽  
Esi Ms

Alda-1 was found to be a poorly bioavailable, 82–86% protein bound, high extraction compound.

Plasma protein binding monitoring of therapeutic drugs in patients using single set of hollow fiber centrifugal ultrafiltration

Bioanalysis ◽  
2017 ◽  
Vol 9 (7) ◽  
pp. 579-592 ◽  
Author(s):  
Xinyu Wang ◽  
Cen Li ◽  
Chaohui Du ◽  
Jing-lin Gao ◽  
Ke-Xin Zhao ◽  
...  
Keyword(s):  
Protein Binding ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Hollow Fiber ◽  
Therapeutic Drugs ◽  
Single Set ◽  
Centrifugal Ultrafiltration
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