Impact of common skin diseases on children in rural Côte d’Ivoire with leprosy and Buruli ulcer co-endemicity: A mixed methods study

Abstract BackgroundNeglected Tropical Diseases (NTDs) comprise 20 communicable diseases that are prevalent in rural poor and remote communities with less access to the health system. For an effective and efficient control, the WHO recommends to affected countries the implementation of integrated control interventions that take into account the different co-endemic NTDs in the same community. However, implementing these integrated interventions involving several diseases with different etiologies, requiring different control approaches and driven by different vertical programs remains a challenge. We report here the results and lessons learned from a pilot test of this integrated approach based on integrated screening of skin diseases in three co-endemic health districts of Côte d'Ivoire, a West African country endemic for Buruli ulcer, leprosy and yaw three skin NTDs. MethodThis cross-sectional study took place from April 2016 to March 2017 in 3 Districts of Côte d’Ivoire co-endemic for BU, leprosy and yaws. It was carried out in 6 stages: identification of potentially co-endemic communities; stakeholder training; social mobilization; mobile medical consultations; case detection and management; and a review meeting.ResultsIn total, 2310 persons were screened with skin diseases. Among them, 07 cases were diagnosed as Buruli ulcer. There were 30 leprosy cases and 15 yaws detected. Other types of ulcerations and skin conditions have been identified and represent the majority of cases detected. We learned from this pilot experience that integration can be successfully implemented in co-endemic communities in Côte d’Ivoire. Health workers are motivated and available to implement integrated interventions instead of interventions focused on a single disease. However, it is essential to provide capacity building, a minimum of drugs and consumables for the care of the patients detected, as well as follow up of detected patients including those with other skin conditions.ConclusionsThe results of this study show that the integration of activities can be successfully implemented in co-endemic communities under the condition of a staff capacity building and a minimal care of the detected patients.

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First Detection of Mycobacterium sp. in Wastewater in Abidjan (Yopougon) Cote d’Ivoire

South Asian Journal of Research in Microbiology ◽

10.9734/sajrm/2020/v7i230167 ◽

2020 ◽

pp. 34-40

Author(s):

Vakou N’dri Sabine ◽

Coulibaly-Kalpy Julien ◽

Amon Lydie Nina ◽

Bernaud Nicolas ◽

Dosso Mireille ◽

...

Keyword(s):

Cote D'ivoire ◽

Urban Areas ◽

Côte D’Ivoire ◽

Skin Diseases ◽

Sampling Site ◽

Buruli Ulcer ◽

Cote D’Ivoire ◽

Côte D'ivoire ◽

Lowenstein Jensen ◽

Wastewater Samples

Non-tuberculous mycobacteria (NTM) are ubiquitous in the environment and worldwide, under certain environmental conditions, they could be responsible for skin diseases or pulmonary lesions. In Ivory Coast, Buruli ulcers endemic country, very little information concerning the epidemiology of NTM in Cote d'Ivoire is known, this ignorance has led to an underestimation of its prevalence in the environment. Aims: The objective of this study was to characterize strains of environmental mycobacteria in wastewater located in urban areas in Abidjan (Yopougon) Côte d'Ivoire. Place and Duration of Study: The study was conducted at Yopougon (Selmer). This site is considered to be Buruli ulcer non-endemic zone according to the national program on fight against Buruli ulcer in Côte d’Ivoire. However, all biological aspect of this work was carried out at the Pastor Institute of Côte d’Ivoire. Methodology: Wastewater samples were collected at the surfaces at Yopougon using the technique described by Britton and Gresson. In the laboratory, these collected samples were treated according to the method described by Stinear et al. and Kankya et al. consisting of decontamination, neutralization followed by culture. Classification of species was done according to the method described by Runyon and collaborators. Biochemical identification of mycobacteria was done according to the method described by Metchock. Results: A total of 32 samples were collected, 8 water samples at each sampling site. After decontamination and culture, specimens grew on Lowenstein-Jensen medium after 7 days (at 37°C and 32°C) and revealed small, smooth, nonpigmented colonies. Smears confirmed the presence of variably acid-fast organisms. Biochemical traits of the isolates revealed, colony grown on Middlebrook agar 7H11 (at 37°C and 32°C); catalase (+); agar (+) (at 37°C and 32°C ); citrate (-); mannitol (-). Conclusion: This work is one of the first study focusing on Mycobacteria in wastewater in Abidjan. The isolation of Mycobacterium sp., an environmental pathogenic organism, supports the hypothesis of possible colonization of urban wastewater by pathogenic mycobacteria. Further studies are needed to verify the involvement of this specie in mycobacterial infections in Côte d'Ivoire.

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Skin disease prevalence study in schoolchildren in rural Côte d'Ivoire: Implications for integration of neglected skin diseases (skin NTDs)

PLoS Neglected Tropical Diseases ◽

10.1371/journal.pntd.0006489 ◽

2018 ◽

Vol 12 (5) ◽

pp. e0006489 ◽

Cited By ~ 23

Author(s):

Rie Roselyne Yotsu ◽

Kouamé Kouadio ◽

Bamba Vagamon ◽

Konan N’guessan ◽

Amari Jules Akpa ◽

...

Keyword(s):

Cote D'ivoire ◽

Skin Disease ◽

Côte D’Ivoire ◽

Skin Diseases ◽

Disease Prevalence ◽

Prevalence Study ◽

Cote D’Ivoire ◽

Côte D'ivoire

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Phytotherapy against buruli ulcer in the Health District of Yamoussoukro (Cote d’Ivoire) : Identification, description, and symbolic functions of the plants and recipes used

Médecine et Santé Tropicales ◽

10.1684/mst.2016.0630 ◽

2016 ◽

Vol 26 (4) ◽

pp. 408-413

Author(s):

A.A. Adjet ◽

D. Kouame ◽

G. Fokou

Keyword(s):

Cote D'ivoire ◽

Côte D’Ivoire ◽

Buruli Ulcer ◽

Health District ◽

Cote D’Ivoire ◽

Côte D'ivoire

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Child case of Buruli ulcer successfully treated through a school‐based skin survey project in Côte d’Ivoire

The Journal of Dermatology ◽

10.1111/1346-8138.15148 ◽

2019 ◽

Vol 47 (2) ◽

Author(s):

Rie R. Yotsu ◽

Chiaki Murase ◽

Konan N’guessan ◽

Aubin Yao ◽

Kouamé Kouadio ◽

...

Keyword(s):

Cote D'ivoire ◽

Côte D’Ivoire ◽

Buruli Ulcer ◽

Cote D’Ivoire ◽

School Based ◽

Côte D'ivoire

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Integrated Approach in the Control and Management of Skin Neglected Tropical Diseases in three health districts of Côte d’Ivoire

10.21203/rs.2.13484/v2 ◽

2019 ◽

Author(s):

Aboa Paul Koffi ◽

Théodore Ange Kouakou Yao ◽

YVES Thierry BAROGUI ◽

Gabriel Diez ◽

Simplice Djakeaux ◽

...

Keyword(s):

Cote D'ivoire ◽

Côte D’Ivoire ◽

Neglected Tropical Diseases ◽

Buruli Ulcer ◽

Integrated Approach ◽

Tropical Diseases ◽

Cote D’Ivoire ◽

Côte D'ivoire ◽

Skin Conditions ◽

Health Districts

Abstract Background Neglected Tropical Diseases (NTDs) comprise 20 communicable diseases that are prevalent in rural poor and remote communities with less access to the health system. For an effective and efficient control, the WHO recommends to affected countries the implementation of integrated control interventions that take into account the different co-endemic NTDs in the same community. However, implementing these integrated interventions involving several diseases with different etiologies, requiring different control approaches and driven by different vertical programs remains a challenge. We report here the results and lessons learned from a pilot test of this integrated approach based on integrated screening of skin diseases in three co-endemic health districts of Côte d'Ivoire, a West African country endemic for Buruli ulcer, leprosy and yaw three skin NTDs. Method This cross-sectional study took place from April 2016 to March 2017 in 3 Districts of Côte d’Ivoire co-endemic for BU, leprosy and yaws. It was carried out in 6 stages: identification of potentially co-endemic communities; stakeholder training; social mobilization; mobile medical consultations; case detection and management; and a review meeting. Results In total, 2310 persons screened had skin lesions at the screening stage. Among them, 07 cases were diagnosed as Buruli ulcer. There were 30 leprosy cases and 15 yaws detected. Other types of ulcerations and skin conditions have been identified and represent the majority of cases detected. We learned from this pilot experience that integration can be successfully implemented in co-endemic communities in Côte d’Ivoire. Health workers are motivated and available to implement integrated interventions instead of interventions focused on a single disease. However, it is essential to provide capacity building, a minimum of drugs and consumables for the care of the patients detected, as well as follow up of detected patients including those with other skin conditions. Conclusions The results of this study show that the integration of activities can be successfully implemented in co-endemic communities under the condition of a staff capacity building and a minimal care of the detected patients.

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Case Report: A New Mycobacterium ulcerans Genotype Causing Buruli Ulcer in Côte d’Ivoire

American Journal of Tropical Medicine and Hygiene ◽

10.4269/ajtmh.20-1307 ◽

2021 ◽

Author(s):

Philippe Bahadoran ◽

Nassim Hammoudi ◽

Alice Gaudart ◽

Jamal Saad ◽

Yoan Di Filippo ◽

...

Keyword(s):

Case Report ◽

Cote D'ivoire ◽

Côte D’Ivoire ◽

Buruli Ulcer ◽

Opportunistic Pathogen ◽

Mycobacterium Ulcerans ◽

Rural Populations ◽

Whole Genome ◽

Cote D’Ivoire ◽

Côte D'ivoire

Mycobacterium ulcerans, the opportunistic pathogen causing Buruli ulcer, is reported to affect rural populations in 36 tropical countries. We report one case of Buruli ulcer in a peri-urban area in Côte d’Ivoire, confirmed by whole genome sequencing which indicated a M. ulcerans genotype previously unreported in Côte d’Ivoire.

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Integrated Approach in the Control and Management of Skin Neglected Tropical Diseases in three health districts of Côte d’Ivoire

10.21203/rs.2.13484/v3 ◽

2020 ◽

Author(s):

Aboa Paul Koffi ◽

Théodore Ange Kouakou Yao ◽

Yves Thierry BAROGUI ◽

Gabriel Diez ◽

Simplice Djakeaux ◽

...

Keyword(s):

Cote D'ivoire ◽

Côte D’Ivoire ◽

Neglected Tropical Diseases ◽

Buruli Ulcer ◽

Integrated Approach ◽

Tropical Diseases ◽

Cote D’Ivoire ◽

Côte D'ivoire ◽

Skin Conditions ◽

Health Districts

Abstract Background Neglected Tropical Diseases (NTDs) comprise 20 communicable diseases that are prevalent in rural poor and remote communities with less access to the health system. For an effective and efficient control, the WHO recommends to affected countries the implementation of integrated control interventions that take into account the different co-endemic NTDs in the same community. However, implementing these integrated interventions involving several diseases with different etiologies, requiring different control approaches and driven by different vertical programs remains a challenge. We report here the results and lessons learned from a pilot test of this integrated approach based on integrated screening of skin diseases in three co-endemic health districts of Côte d'Ivoire, a West African country endemic for Buruli ulcer, leprosy and yaw. Method This cross-sectional study took place from April 2016 to March 2017 in 3 Districts of Côte d’Ivoire co-endemic for BU, leprosy and yaws. It was carried out in 6 stages: identification of potentially co-endemic communities; stakeholder training; social mobilization; mobile medical consultations; case detection and management; and a review meeting. Results We have included in the study all patients with ‘skin signs and symptoms at the screening stage who accepted voluntarily to be screened. In total, 2310 persons screened had skin lesions at the screening stage. Among them, 07 cases were diagnosed as Buruli ulcer. There were 30 leprosy cases and 15 yaws detected. Other types of ulcerations and skin conditions have been identified and represent the majority of cases detected. We learned from this pilot experience that integration can be successfully implemented in co-endemic communities in Côte d’Ivoire. Health workers are motivated and available to implement integrated interventions instead of interventions focused on a single disease. However, it is essential to provide capacity building, a minimum of drugs and consumables for the care of the patients detected, as well as follow up of detected patients including those with other skin conditions. Conclusions The results of this study show that the integration of activities can be successfully implemented in co-endemic communities under the condition of a staff capacity building and a minimal care of the detected patients.

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Integrated Approach in the Control and Management of Skin Neglected Tropical Diseases in Three Health Districts of Côte d’Ivoire

10.21203/rs.2.13484/v4 ◽

2020 ◽

Author(s):

Aboa Paul Koffi ◽

Théodore Ange Kouakou Yao ◽

Yves Thierry BAROGUI ◽

Gabriel Diez ◽

Simplice Djakeaux ◽

...

Keyword(s):

Cote D'ivoire ◽

Côte D’Ivoire ◽

Neglected Tropical Diseases ◽

Buruli Ulcer ◽

Integrated Approach ◽

Tropical Diseases ◽

Cote D’Ivoire ◽

Côte D'ivoire ◽

Skin Conditions ◽

Health Districts

Abstract Background: Neglected tropical diseases (NTDs) comprise 20 communicable diseases that are prevalent in rural poor and remote communities with less access to the health system. For effective and efficient control, the WHO recommends that affected countries implement integrated control interventions that take into account the different co-endemic NTDs in the same community. However, implementing these integrated interventions involving several diseases with different etiologies, requiring different control approaches and driven by different vertical programs, remains a challenge. We report here the results and lessons learned from a pilot test of this integrated approach based on integrated screening of skin diseases in three co-endemic health districts of Côte d'Ivoire, a West African country endemic for Buruli ulcer, leprosy and yaw.Method: This cross-sectional study took place from April 2016 to March 2017 in 3 districts of Côte d’Ivoire co-endemic for BU, leprosy and yaws. The study was carried out in 6 stages: identification of potentially co-endemic communities; stakeholder training; social mobilization; mobile medical consultations; case detection and management; and a review meeting.Results: We included in the study all patients with skin signs and symptoms at the screening stage who voluntarily accepted screening.In total, 2310 persons screened had skin lesions at the screening stage. Among them, 07 cases were diagnosed with Buruli ulcer. There were 30 leprosy cases and 15 yaws detected. Other types of ulcerations and skin conditions have been identified and represent the majority of cases detected. We learned from this pilot experience that integration can be successfully implemented in co-endemic communities in Côte d’Ivoire. Health workers are motivated and available to implement integrated interventions instead of interventions focused on a single disease. However, it is essential to provide capacity building, a minimum of drugs and consumables for the care of the patients identified, as well as follow-up of identified patients, including those with other skin conditions.Conclusions: The results of this study show that the integration of activities can be successfully implemented in co-endemic communities under the condition of staff capacity building and minimal care of identified patients.

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