Reproducibility of Double Indicator Dilution Measurements of Intrathoracic Blood Volume Compartments, Extravascular Lung Water, and Liver Function

CHEST Journal ◽  
1998 ◽  
Vol 113 (4) ◽  
pp. 1070-1077 ◽  
Author(s):  
Oliver Godje ◽  
Marcus Peyerl ◽  
Tobias Seebauer ◽  
Oliver Dewald ◽  
Bruno Reichart
Keyword(s):  
Liver Function ◽  
Blood Volume ◽  
Extravascular Lung Water ◽  
Indicator Dilution ◽  
Intrathoracic Blood Volume ◽  
Lung Water ◽  
Double Indicator Dilution

Indicator dilution using a fluorescent indicator

1982 ◽  
Vol 52 (5) ◽  
pp. 1368-1374 ◽  
Author(s):  
V. B. Elings ◽  
F. R. Lewis ◽  
J. Briggs
Keyword(s):  
Extravascular Lung Water ◽  
Detection System ◽  
Indicator Dilution ◽  
Fluorescent Light ◽  
Left Heart ◽  
Lung Water ◽  
Fluorescent Indicator ◽  
Double Indicator Dilution

In vitro and in vivo indicator-dilution measurements are made with a fluorescent indicator and a novel detection system using a catheter containing a single optical fiber that carries both the exciting and returning fluorescent light. These fluorescent-dilution measurements are compared with simultaneous green dye-dilution measurements. The double-indicator-dilution measurement of extravascular lung water using heat and fluorescence is compared with gravimetric measurements. Also investigated is the sensitivity of the fluorescent measurement to changes in O2 saturation and hematocrit of the blood. An example of the measurement of a right-to-left heart shunt with this new indicator is given.

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