scholarly journals Biomarkers in low cardiac output syndrome after open cardiac surgery in children

2021 ◽  
Vol 61 (4) ◽  
pp. 223-8
Author(s):  
Reby Kusumajaya ◽  
Najib Advani ◽  
Piprim B. Yanuarso ◽  
Zulham Effendy
Keyword(s):  
Cardiac Output ◽  
Cardiac Surgery ◽  
Lactate Level ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
High Pco2 ◽  
Open Heart ◽  
Low Cardiac Output Syndrome ◽  
Low Cardiac Output ◽  
Pco2 Gap

Background Corrective cardiac surgery is the standard management for complex congenital heart disease. Cardiopulmonary bypass surgery and post-surgical intensive care may lead to low cardiac output syndrome (LCOS), as a major complication after open heart surgery.  To diagnose early LCOS, lactate level, pCO2 gap, and mixed venous oxygen saturation (SvO2) are parameters reported to have correlations with decreased cardiac output, morbidity, and post-cardiac surgery mortality. Objective To determine the usefulness of lactate level, pCO2 gap (arterial-vein), and SvO2 for early detection of LCOS in children post-open heart surgery. Methods This prospective cohort study was done from August to October 2017 in the ICU of the Integrated Cardiac Center, Dr. Cipto Mangunkusumo Hospital, Jakarta. Subjects were pediatric patients who underwent cardiac surgery. After surgery, patients underwent monitoring in the ICU for clinical signs of LCOS and examinations for lactate levels, pCO2 gap, and SvO2 at 15 minutes, 4 hours and 8 hours. Results Thirty-three open heart surgery patients were the subjects. Lactate level at 4 hours and 8 hours post-operative were significantly higher in the LCOS group compared to non-LCOS group. For the pCO2 gap, only the 4-hour post-operative results were significantly higher in LCOS group compared to non-LCOS groups. In addition, only SvO2 at 4 hours after surgery was significantly lower in LCOS group compared to non-LCOS group. Conclusion Elevated lactate, high pCO2 gap, as well as decreased SvO2 at 4 hours post-operatively are the most reliable markers of LCOS after pediatric open heart surgery.

scholarly journals A.14 Low cardiac output syndrome after open-heart surgery: intraoperative risk factors

1996 ◽  
Vol 76 ◽  
pp. 4-5
Author(s):  
S. Garrido ◽  
M.J. Martín ◽  
S. Rodiño ◽  
J. Llorens ◽  
C.R. Valdés ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiac Output ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Low Cardiac Output Syndrome ◽  
Low Cardiac Output

scholarly journals Organ failures due to low cardiac output syndrome following open heart surgery.

1986 ◽  
Vol 50 (4) ◽  
pp. 329-335 ◽  
Author(s):  
KEIJI KUMON ◽  
KAZUHIKO TANAKA ◽  
TAKAHIKO HIRATA ◽  
YASUAKI M.D NAITO ◽  
TSUYOSHI FUJITA
Keyword(s):  
Cardiac Output ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Low Cardiac Output Syndrome ◽  
Low Cardiac Output ◽  
Organ Failures

scholarly journals Hypothermia for the Management of Low Cardiac Output Syndrome after Open Heart Surgery.

1993 ◽  
Vol 22 (2) ◽  
pp. 118-122
Author(s):  
Yoshifumi IGURO ◽  
Hitoshi TOYOHIRA ◽  
Shinzi SHIMOKAWA ◽  
Yuusuke UMEBAYASHI ◽  
Shigeru FUKUDA ◽  
...  
Keyword(s):  
Cardiac Output ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Low Cardiac Output Syndrome ◽  
Low Cardiac Output

scholarly journals Gastric Tonometry in Open-Heart Surgery Patients without Low Cardiac Output Syndrome

1994 ◽  
Vol 1 (2) ◽  
pp. 107-110
Author(s):  
Toru Takahashi ◽  
Fumio Kunimoto ◽  
Susumu Ishikawa ◽  
Akio Ohtaki ◽  
Yasuo Morishita ◽  
...  
Keyword(s):  
Cardiac Output ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Gastric Tonometry ◽  
Open Heart ◽  
Low Cardiac Output Syndrome ◽  
Low Cardiac Output

The implications of Milrinone Lactate in the Postoperative Clinical Management of Surgical Interventions for Congenital Heart Malformations in Children

2017 ◽  
Vol 68 (11) ◽  
pp. 2658-2661
Author(s):  
Mariana Anisoara (Ciorba) Puiac ◽  
Horatiu Suciu ◽  
Marius Ilie Ciorba ◽  
Mihaela Maria Opris ◽  
Hussam Al Hussein ◽  
...  
Keyword(s):  
Cardiac Output ◽  
Congenital Heart ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Hemodynamic Parameters ◽  
Low Cardiac Output Syndrome ◽  
Low Cardiac Output ◽  
Congenital Heart Malformations ◽  
Heart Malformations

The purpose of the study was to prove to efficacy of Milrinone in the management of open heart surgery in children with congenital heart malformations, the link between Milrinone efficacy and the prevention of low cardiac output syndrome and Milrinone side effects. We conducted a retrospective study on a group of 24 patients, admitted to the Tg Mures Emergency Institute for Cardiovascular Diseases and Transplant, between August 2016 and February 2017. Milrinone was administered to children that underwent open heart surgery for different congenital heart malformations, using doses between 0.25 and 0.75 mcg per kg bodyweight, in continuous intravenous drip, before de-clamping of the Aorta, the procedures being conducted in extracorporeal circulation. We recorded demographic data, biological parameters of renal function, myocardial function and hemodynamic parameters, before and after surgery. The administration of Milrinone determined a reduction of incidence of low cardiac output syndrome, registering only 4 deaths, the survival rate being 83.33%, 13 cases presenting complications. Postoperatively we registered a significant improvement of the mean heart rate. Milrinone proved efficient in the re-establishment of hemodynamic parameters in patients with this type of clinical manifestations. Using Milrinone in children that undergo open heart surgery determines a decrease in incidence of low cardiac output syndrome, its� presence in the pharma market being necessary.

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