A STUDY OF CORRELATION OF PREOPERATIVE FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) WITH HISTOPATHOLOGICAL EXAMINATION (HPE) IN GOITRE

Cysticercosis is a systemic parasitic disease caused by the larval form of cestodeT. solium. It has a worldwide distribution and is potentially harmful with variable clinical manifestations. The patient most commonly presents with subcutaneous and muscle involvement in the form of nodular lesions. The other most commonly involved sites include eye, brain, bladder wall, and heart. Cysticercosis can be diagnosed on serology, and radiologically but confirmatory diagnosis is based on histopathological examination of the involved tissue biopsy specimen. Fine needle aspiration cytology is a useful low-cost outpatient procedure tool for preoperative diagnosis of cysticercosis and is absolutely essential for diagnosis of the parasitic lesions in a peripheral hospital, one like ours.

Download Full-text

Fine needle aspiration cytology in feline skeletal muscle as a diagnostic tool for extramedullary plasmacytoma

Arquivo Brasileiro de Medicina Veterinária e Zootecnia ◽

10.1590/1678-4162-9180 ◽

2017 ◽

Vol 69 (3) ◽

pp. 587-592

Author(s):

D.B. Martins ◽

C.K. Rossato ◽

S.L. Silva ◽

S.S.N. Almeida ◽

L.S. Ribeiro

Keyword(s):

Skeletal Muscle ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Needle Aspiration ◽

Extramedullary Plasmacytoma ◽

Feline Leukemia Virus ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology

ABSTRACT Extramedullary noncutaneous plasmacytoma (ENP) is a myeloproliferative disorder of plasma cells that rarely affects cats. This paper describes an ENP case revealed by fine needle aspiration cytology (FNAC) of the mass in the skeletal muscle of an 8-month-old, male, mixed breed cat, which had a nodule in the left hind limb. The rapid immunoassay test confirmed the presence of feline leukemia virus (FeLV). The animal necropsy macroscopically showed the nodule came from the semimembranosus muscle. Histopathological examination ratified the cytological findings. Thus, this paper alerts to the existence of plasmacytoma located in the skeletal muscle of feline species. FNAC is a quick and efficient method for diagnosis of ENP.

Download Full-text

Accuracy of Fine Needle Aspiration Cytology (FNAC) in comparison to histopathological examination for the diagnosis of thyroid swellings

International Journal of Medical Science and Public Health ◽

10.5455/ijmsph.2016.30042016536 ◽

2017 ◽

Vol 6 (1) ◽

pp. 6 ◽

Cited By ~ 1

Author(s):

Divyesh Goswami ◽

Preeti Agrawal ◽

Princy Shinde

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology

Download Full-text

Fine-needle aspiration cytology of pilomatrixoma: A short series of three cases

CytoJournal ◽

10.4103/1742-6413.144689 ◽

2014 ◽

Vol 11 ◽

pp. 30 ◽

Cited By ~ 8

Author(s):

Jitendra Singh Nigam ◽

Savitri Singh

Keyword(s):

Head And Neck ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Neck Region ◽

Middle Finger ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology

Pilomatrixoma (PMX) (pilomatricoma, calcifying epithelioma of Malherbe) is a benign tumor with differentiation toward the hair matrix cells and is common in head and neck region. It is most commonly seen in the first two decades of life and presents as a subcutaneous, small, asymptomatic firm solitary nodule. Fine-needle aspiration cytology (FNAC) has been described as an important preoperative diagnostic investigation though on cytology the diagnosis of PMX is sometimes difficult and misdiagnosed. We describe two patients with gradually increasing asymptomatic swelling on pinna and middle finger. FNAC was done and a diagnosis of PMX was given, further confirmed by histopathological examination. The present cases highlight the importance of FNAC in considering PMX as differential diagnosis of dermal or subcutaneous nodules in locations other than head and neck. Cytopathologists who play an important role in the preliminary diagnosis should keep in mind the variability of the cellular composition of these types of lesions to avoid misdiagnosis.

Download Full-text

Correlation of ultrasonography and fine needle aspiration cytology for diagnosis of malignancy in thyroid lesions: a study of 100 cases

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20212787 ◽

2021 ◽

Author(s):

E. Pavan Kumar ◽

S. Namratha ◽

Siva Subba Rao Pakanati ◽

Uma Pokala

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Needle Aspiration ◽

Prospective Clinical Study ◽

Specific Information ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology ◽

Thyroid Lesions

Background: The majority (90%) of thyroid lesions are benign as malignancy occurs only 1 in 10 thyroid nodules. The purpose of ultrasonography (USG) and fine needle aspiration cytology (FNAC) is to pick the patients having malignancy for surgical intervention. The objective of present study is to correlate ultrasonography findings with FNAC for diagnosis of malignancy in thyroid lesions by relating these findings to histopathological examination (HPE) reports.Methods: A prospective clinical study carried out from September 2019 to February 2021, in the Department of Ear Nose and Throat (ENT), Mamata Medical College, Khammam, in patients with clinical evidence of thyroid swelling. Ultrasound and FNAC were done in all cases and HPE were done in cases where surgeries were performed at our institution. The results were analysed. Results: According to USG, out of 100 cases 93 cases were found to be of benign thyroid swellings, 4 cases were suspected malignant and 3 cases were found malignant. According to FNAC, out of 100 cases 97 cases were benign and 3 cases were confirmed to be malignant. Two cases which were found to be malignant on both USG and FNAC were confirmed as malignant according to HPE report.Conclusions: USG is a sensitive modality in the assessment of thyroid swellings with good accuracy. FNAC also provides the most direct and specific information about thyroid lesions. It is suggested that USG followed by FNAC provides better diagnosis in thyroid lesions.

Download Full-text

A large malignant oncocytoma of parotid gland: a case report

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20205079 ◽

2020 ◽

Vol 6 (12) ◽

pp. 2310

Author(s):

Nidhi S. Mohan ◽

Sunita S. Vernekar ◽

Mohammed M. Abus Samee ◽

Manjunath D.

Keyword(s):

Salivary Gland ◽

Parotid Gland ◽

Fine Needle Aspiration ◽

Facial Palsy ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology

Malignant oncocytoma is an extremely rare neoplasm of the salivary gland accounting for 0.5% of epithelial salivary gland malignancies and 0.18% of epithelial salivary gland tumors. We report a case of malignant oncocytoma of left parotid gland in a 61-year old female patient. Patient presented with a 6-year history of painless swelling in the left parotid region. Fine needle aspiration cytology of the swelling was suggestive of pleomorphic adenoma. A computed tomography scan performed did not reveal any features suggestive of malignancy. Patient underwent left superficial parotidectomy. However, histopathological examination of the specimen turned out to be malignant oncocytoma. Malignant oncocytoma of salivary glands have rare incidence and may have similar morphologic features with other neoplasms. Despite the tumor being large and malignant in this case, there was no facial palsy preoperatively. As histopathology is often diagnostic, the possibility of malignancy always must be kept in mind preoperatively even when there is no facial palsy or fine needle aspiration cytology not showing up malignancy.

Download Full-text

A study of correlation of fine-needle aspiration cytology with postoperative histopathological examination in patients with either solitary thyroid nodule or multiple nodules

The Scientific Journal of Al-Azhar Medical Faculty Girls ◽

10.4103/sjamf.sjamf_7_18 ◽

2018 ◽

Vol 2 (2) ◽

pp. 41

Author(s):

MaherF Badr ◽

MohammedA Sirry ◽

ElsayedM Abdelwahab ◽

HebaT Abdelaziz

Keyword(s):

Thyroid Nodule ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Solitary Thyroid Nodule ◽

Needle Aspiration Cytology ◽

Multiple Nodules

Download Full-text

Accuracy Of Fine Needle Aspiration Cytology (FNAC) In The Diagnosis Of Thyroid Swellings

Journal of Dhaka National Medical College & Hospital ◽

10.3329/jdnmch.v18i2.16023 ◽

2013 ◽

Vol 18 (2) ◽

pp. 47-51 ◽

Cited By ~ 1

Author(s):

Md Alamgir Hossain Sikder ◽

AZM Mahfuzur Rahman ◽

Md Abul Khair

Keyword(s):

Thyroid Gland ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Needle Aspiration ◽

Histopathological Diagnosis ◽

Aspiration Cytology ◽

Female Ratio ◽

Fine Needle ◽

Needle Aspiration Cytology

Objective: To evaluate the accuracy of fine needle aspiration cytology (FNAC) in comparison to paraffin section in thyroid swelling. Study design: Cross sectional study. Place and duration of study: Department of Surgery, Bangabandhu Sheikh Mujib Medical University from July 2009 to June 2011. Patient and method: One hundred patients with enlarged thyroid gland of both sexes were selected from admitted patient of Surgery department. All patients had preoperative FNAC, performed by pathologist at the Histopathology department and postoperative specimen were also examined and histopathological diagnosis were made. All FNAC diagnosis were correlated with the histopathological diagnosis. Results: Out of 100 patients 23 were male and 77 were female, male-female ratio 1: 3.3. In FNAC 76 patients were diagnosed as benign lesion of which 8 were later diagnosed as malignant on histopathological examination (68 were true negative 8 were false negative). 22 cases were diagnosed as malignant, both on FNAC and histopathological examination. Only 2 cases were diagnosed as follicular neoplasm on FNAC but on histopathological examination diagnosed as follicular carcinoma (22 cases were true positive) in this study. Overall sensitivity of FNAC were 68.75%, specificity 100.00% and accuracy 90%; PPV=100% & NPV=87.18% Conclusion: FNAC is a reliable, safe and accurate method as a preoperative evaluation in thyroid gland swelling before surgery. FNAC has more accuracy and specificity in detecting thyroid gland malignancy and therefore it is a reliable diagnostic test for evaluating thyroid swellings. DOI: http://dx.doi.org/10.3329/jdnmch.v18i2.16023 J. Dhaka National Med. Coll. Hos. 2012; 18 (02): 47-51

Download Full-text

FINE NEEDLE ASPIRATION CYTOLOGY AS A DIAGNOSTIC TOOL; AN ASSESSMENT

International Medical Science Research Journal ◽

10.51594/imsrj.v1i2.62 ◽

2020 ◽

Vol 1 (2) ◽

pp. 32-44

Author(s):

Do Thi Trang ◽

Duong Thi Dung ◽

Tran Thi Minh Thu

Keyword(s):

Fine Needle Aspiration ◽

Diagnostic Tool ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Needle Aspiration ◽

Breast Lesions ◽

Negative Consequences ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology

The study is about breast lesions which is a common cause of mortality and morbidity among females. To avoid negative consequences, there is need for urgent diagnosis and treatment. Fine Needle Aspiration Cytology (FNAC) is a useful diagnostic tool and possess higher level of accuracy. In this study, the objective was to determine the accuracy of FNAC in diagnosis of palpable breast lumps. Additionally, the objective was to find the correlation between cytological findings and histopathological examination of surgical specimens. The methodology of the study was based on retrospective study method. FNAC of breast lump was conducted on 271 patients out of which 104 formed the base group. The results showed that there were 104 patients of base study who had average age of 32 years. There were 54 patients with lump in left breasts, and 46 patients with lump in right breasts and 4 patient had bilateral lump. There were 77 patients with benign, 34 patients with malignant, and 3 had atypica;/suspicious lesions on cytological examination. Based on histopathological examination, 77 cases were related to benign, 26 were related to malignant, and 1 with atypical/suspicious. Cyto-histological concurrence was 93.05% and 79.2% for Fibroadenoma and Infiltrating ductal carcinoma respectively. Overall sensitivity of FNAC procedure was 94.17%, specificity 100% and accuracy 93.26%. On the basis of result, it is concluded that FNAC is a simple, reliable method for diagnosis of both benign and malignant lesions and can be used in the evaluation of breast lesions.

Download Full-text

Comparative study of fine needle aspiration cytology and histopathology of thyroid swellings in tertiary health centre

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20214900 ◽

2021 ◽

Vol 8 (1) ◽

pp. 53

Author(s):

Gangadhara K. S. ◽

Chaitanya Vadva ◽

Sridhara S.

Keyword(s):

Fine Needle Aspiration ◽

Predictive Value ◽

Fine Needle Aspiration Cytology ◽

Histopathological Examination ◽

Health Centre ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Thyroid Swelling ◽

Needle Aspiration Cytology

Background: Thyroid swelling being the most common presentation in ENT clinical practice, a prospective study was done to assess the role of Fine needle aspiration cytology in diagnosing the nature of thyroid swellings and comparing its results with histopathological examination findings.Methods: This is a prospective institutional based study comparing cytology and corresponding histopathology findings reported in 60 cases of thyroid swelling. The statistical analysis included sensitivity, specificity, positive predictive value, negative predictive value and accuracy in thyroid swelling.Results: Out of 60 cases, FNAC showed 93.3% and 6.6% of benign and malignant cases respectively whereas HPE showed 86.7% and 13.3% of benign and malignant cases respectively. On FNAC-HPE correlation using HPE as standard reference the diagnostic accuracy of present study is 91.66%.Conclusions: It was observed that FNAC is a reliable tool, safe and accurate method in evaluating thyroid swelling thus having great influences in treatment decision. Thus FNAC is the investigation of choice in thyroid swellings with excellent patient compliance, simple, safe and cost effective.

Download Full-text