scholarly journals OUTCOME OF ACUTE LIVER FAILURE DUE TO HEPATITIS A TREATED WITH MEDICAL MANAGEMENT

2016 ◽  
Vol 5 (17) ◽  
pp. 834-837
Author(s):  
Thulaseedharan Nallaveettil Kesavan ◽  
Shajit Sadanand ◽  
Arun Thomas Edathumpadikal Thomas ◽  
Bhagya Shaji
2020 ◽  
Vol 14 (4) ◽  
pp. 483-490
Author(s):  
Bikrant Bihari Lal ◽  
Vikrant Sood ◽  
Pandey Snehavardhan ◽  
Rajeev Khanna ◽  
Samba Siva Rao Pasupuleti ◽  
...  

2014 ◽  
Vol 61 (3) ◽  
pp. 456-458 ◽  
Author(s):  
Heng Chi ◽  
Elizabeth B. Haagsma ◽  
Annelies Riezebos-Brilman ◽  
Arie P. van den Berg ◽  
Herold J. Metselaar ◽  
...  

2017 ◽  
Vol 32 (1) ◽  
pp. e13140 ◽  
Author(s):  
Dong-Hwan Jung ◽  
Shin Hwang ◽  
Young-Suk Lim ◽  
Ki-Hun Kim ◽  
Chul-Soo Ahn ◽  
...  

Author(s):  
FK Chiou ◽  
V Logarajah ◽  
CWW Ho ◽  
LSH Goh ◽  
SV Karthik ◽  
...  

Introduction: The aetiology of paediatric acute liver failure (PALF) varies widely according to age, and geographic and socioeconomic factors. This study aimed to examine the epidemiology, aetiology and outcome of PALF in Singapore at a single centre. Methods: A retrospective review was performed of patients aged 0–18 years who were diagnosed with PALF from 2007 to 2019. PALF was defined by: absence of chronic liver disease; biochemical evidence of acute liver injury; and coagulopathy, non-correctible by vitamin K, defined as prothrombin time (PT) ≥ 20 seconds or international normalised ratio (INR) ≥ 2.0 regardless of hepatic encephalopathy (HE) or PT ≥ 15 seconds or INR ≥ 1.5 in the presence of HE. Results: 34 patients were included. Median age at diagnosis was 10 months (range 7 days to 156 months). The top three causes of PALF were indeterminate (41.2%), metabolic (26.5%) and infectious (26.5%) aetiologies. A metabolic disorder was the most frequent aetiology in infants < 12 months (38.9%), whereas an indeterminate cause was the most common in children > 12 months (50%). No cases of viral hepatitis A or B presenting with PALF were detected. Overall spontaneous recovery rate (survival without liver transplantation [LT]) was 38.2%, and overall mortality rate was 47.1%. Six patients underwent living-donor LT, and the post-transplant survival at one year was 83.3%. Conclusion: The aetiologic spectrum of PALF in Singapore is similar to that in developed Western countries, with indeterminate aetiology accounting for the majority. PALF is associated with poor overall survival; hence, timely LT for suitable candidates is critical to improve survival outcomes.


2020 ◽  
Vol 44 (3) ◽  
pp. e61-e63
Author(s):  
Ignacio García-Juárez ◽  
Alejandro Campos-Murguía ◽  
Braulio A. Marfil-Garza ◽  
Godolfino Miranda ◽  
Edgar A. Granados ◽  
...  

2014 ◽  
Vol 55 (4) ◽  
pp. 953 ◽  
Author(s):  
Hye Sun Shin ◽  
Sae Pyul Kim ◽  
Sang Hoon Han ◽  
Do Young Kim ◽  
Sang Hoon Ahn ◽  
...  

2018 ◽  
pp. 155-173
Author(s):  
Heli Bhatt ◽  
Girish S. Rao

2014 ◽  
Vol 53 (1) ◽  
pp. 309-310 ◽  
Author(s):  
Susan K. Wollersheim ◽  
Romney M. Humphries ◽  
James D. Cherry ◽  
Paul Krogstad

We describe a case of acute liver failure caused by echovirus 25 (E25) in a previously healthy 2-year-old boy. Initial serological studies were consistent with hepatitis A virus (HAV), with prozone phenomenon. The similarity of E25 to HAV may obscure accurate diagnosis in some cases of hepatitis.


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