Mantle Cell Lymphoma of the Gastrointestinal Tract: A Case Series and Review of the Literature for Gastroenterologists

2013 ◽  
Vol 108 ◽  
pp. S380
Author(s):  
Nathan Yeasted ◽  
Elliot Epner ◽  
Matt Moyer ◽  
Francesca Ruggiero ◽  
Thomas McGarrity
Keyword(s):  
Gastrointestinal Tract ◽  
Mantle Cell Lymphoma ◽  
Cell Lymphoma ◽  
Case Series ◽  
Review Of The Literature ◽  
Mantle Cell

Mantle Cell Lymphoma Presenting with Unusual Morphology in an Adolescent Female: A Case Report and Review of the Literature

2006 ◽  
Vol preprint (2007) ◽  
pp. 1
Author(s):  
Kristi Smock ◽  
Hassan Yaish ◽  
Mitchell Cairo ◽  
Mark Lones ◽  
Carlynn Willmore-Payne ◽  
...  
Keyword(s):  
Case Report ◽  
Mantle Cell Lymphoma ◽  
Cell Lymphoma ◽  
Adolescent Female ◽  
Review Of The Literature ◽  
Mantle Cell

scholarly journals Mantle cell lymphoma and chronic lymphocytic leukemia: report of a rare disease association and review of the literature

2010 ◽  
Vol 3 (2-3) ◽  
pp. 91-99 ◽  
Author(s):  
Joana Perdigão ◽  
Helena Alaiz ◽  
Paulo Lúcio ◽  
Paula Gameiro ◽  
Marta Sebastião ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Mantle Cell Lymphoma ◽  
Rare Disease ◽  
Cell Lymphoma ◽  
Disease Association ◽  
Lymphocytic Leukemia ◽  
Review Of The Literature ◽  
Mantle Cell

CD10-positive mantle cell lymphoma: biologically distinct entity or an aberrant immunophenotype? Insight, through gene expression profile in a unique case series

2015 ◽  
Vol 68 (10) ◽  
pp. 844-848 ◽  
Author(s):  
Ariz Akhter ◽  
Etienne Mahe ◽  
Lesley Street ◽  
Payam Pournazari ◽  
Marco Perizzolo ◽  
...  
Keyword(s):  
Gene Expression ◽  
Mantle Cell Lymphoma ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Cell Lymphoma ◽  
Somatic Hypermutation ◽  
Case Series ◽  
Convincing Evidence ◽  
Minimal Impact ◽  
Mantle Cell

BackgroundMantle cell lymphoma (MCL) is an aggressive disease with genetic heterogeneity and discrete clinical subtypes. MCL is rarely CD10 positive. These cases raise the question whether a subset of MCL may be germinal centre (GC) derived, and have distinct clinicopathological characteristics.Aims and methodsA series of nine CD10-positive MCL cases is described herein. The clinicopathological and immunophenotypic features, immunoglobulin somatic hypermutation (SHM) status and gene expression profile (GEP) data are detailed. These features were compared with two independent sets (n=20, each) of CD10-negative MCL cases (controls), which were randomly selected from our institutional registry.ResultsGEP showed distinct expression of a GC signature in CD10-positive MCL cases with minimal impact on downstream signalling pathways. There were no significant differences in the clinicopathological features or clinical outcome between our CD10-positive and CD10-negative MCL cases. The frequency of SHM was comparable with established data.ConclusionsThis study provides convincing evidence that CD10 expression is related to a distinct GC signature in MCL cases, but without clinical or biological implications.

Mantle Cell Lymphoma of the Soft Palate. A Case Report and Review of the Literature

2015 ◽  
Vol 120 (3) ◽  
pp. e167
Author(s):  
S. TITSINIDES ◽  
M. GEORGAKI ◽  
N. NIKITAKIS ◽  
E. PIPERI ◽  
P. PANAYOTIDIS
Keyword(s):  
Case Report ◽  
Mantle Cell Lymphoma ◽  
Soft Palate ◽  
Cell Lymphoma ◽  
Review Of The Literature ◽  
Mantle Cell

Rituximab-Induced Acute Severe Thrombocytopenia: A Case Series in Patients With Mantle Cell Lymphoma

2013 ◽  
Vol 13 (5) ◽  
pp. 602-605 ◽  
Author(s):  
Santhosh K. Sadashiv ◽  
Rohit Rao ◽  
Salman Fazal ◽  
John Lister
Keyword(s):  
Mantle Cell Lymphoma ◽  
Cell Lymphoma ◽  
Case Series ◽  
Severe Thrombocytopenia ◽  
Mantle Cell

scholarly journals Mantle Cell Lymphoma of the Gastrointestinal Tract (Lymphomatous Polyposis)

1996 ◽  
Vol 10 (3) ◽  
pp. 144-148
Author(s):  
Hugh James Freeman
Keyword(s):  
Gastrointestinal Tract ◽  
Mantle Cell Lymphoma ◽  
Cell Lymphoma ◽  
Mantle Cell ◽  
History Of ◽  
Postmortem Studies ◽  
Gastrointestinal Lymphomas ◽  
Aggressive Clinical Course ◽  
Widespread Dissemination ◽  
Entire Gastrointestinal Tract

A74-year-old male with a history of a tonsillar lymphoma developed diarrhea. Investigations led to detection of extensive intestinal lymphomatous polyposis (mantle cell lymphoma). After an aggressive clinical course with associated nodal and peripheral blood involvement, death followed within three months. Postmortem studies revealed widespread dissemination within the entire gastrointestinal tract, including the esophagus, stomach, and small and large intestines. Although this type of lymphoma is rare and accounts for only about 1% to 8% of all forms of primary B cell gastrointestinal lymphomas in North America, separation from other subtypes has become more important because of reported responses of mucosa-associated lymphoid tissue-lymphomas to antibiotics aimed atHelicobacter pylorieradication.

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