315 Can Adenoma Detection Rates Predict a Benchmark for Serrated Polyp and Advanced Adenoma Detection Rates in a Diverse Urban Population?

2019 ◽  
Vol 114 (1) ◽  
pp. S186-S186
Author(s):  
Shaman Dalal ◽  
Aun Shah ◽  
Patrick Twohig ◽  
Aakash Desai ◽  
Dalbir S. Sandhu
Endoscopy ◽  
2017 ◽  
Vol 49 (11) ◽  
pp. 1051-1060 ◽  
Author(s):  
Konstantinos Triantafyllou ◽  
Dimitrios Polymeros ◽  
Periklis Apostolopoulos ◽  
Catarina Lopes Brandao ◽  
Paraskevas Gkolfakis ◽  
...  

Abstract Background and study aims The Endocuff (ARC Medical Design, Leeds, UK) is a device that, when mounted on the tip of an endoscope, may assist with inspection of a greater surface of the colonic mucosa by pulling backwards, flattening, and stretching the colonic folds as the endoscope is gradually withdrawn. We aimed to compare the adenoma miss rates of Endocuff-assisted colonoscopy with those of conventional colonoscopy. Patients and methods The included patients underwent same-day, back-to-back, (Endocuff-assisted colonoscopy as the index procedure followed by conventional colonoscopy or vice versa, randomly assigned 1:1) colonoscopies, performed by six endoscopists with documented adenoma detection rates > 35 %, in four tertiary endoscopy facilities. Results We randomized 200 patients (mean age 61.2 years [standard deviation 9.8]; 86.5 % colorectal cancer screening surveillance cases). Overall, there were seven incomplete examinations using Endocuff and one with conventional colonoscopy (P = 0.03). Times for endoscope insertion (5.0 minutes [0.8 – 21.0] vs. 5.0 minutes [1.0 – 16.0]; P = 0.49) and withdrawal (6.0 minutes [3.2 – 29.0] vs. 6.0 minutes [3.1 – 17.0]; P = 0.06) were similar for Endocuff-assisted and conventional colonoscopy. We detected one cancer and 195 adenomas; 84 in the proximal colon. Endocuff-assisted colonoscopy showed significantly lower overall and proximal colon adenoma miss rates compared with conventional colonoscopy (14.7 % [8.0 % – 21.0 %] vs. 38.4 % [28.1 % – 48.6 %] and 10.4 % [1.8 % – 19.1 %] vs. 38.9 % [23.0 % – 54.8 %], respectively). No difference between the two arms was shown regarding advanced adenoma miss rates, either overall or in the proximal colon. There were no serious adverse events related to the procedures. Conclusions In comparison with conventional colonoscopy, Endocuff-assisted colonoscopy has a significantly lower adenoma miss rate when performed by high-detector endoscopists. However, the incomplete colonoscopy rate with Endocuff is higher.ClinicalTrials.gov Identifier: NCT02340065.


2016 ◽  
Vol 83 (5) ◽  
pp. AB549
Author(s):  
Jennifer Nayor ◽  
Sergey Goryachev ◽  
Vivian S. Gainer ◽  
John R. Saltzman

2014 ◽  
Vol 146 (5) ◽  
pp. S-410
Author(s):  
Anand S. Shah ◽  
Heval Mohamed Kelli ◽  
Lauren M. Shea ◽  
Stephan U. Goebel ◽  
Emad S. Qayed

2019 ◽  
Vol 07 (11) ◽  
pp. E1344-E1354 ◽  
Author(s):  
Stacey A. Fedewa ◽  
Joseph C. Anderson ◽  
Christina M. Robinson ◽  
Julie E. Weiss ◽  
Robert A. Smith ◽  
...  

Abstract Background and study aims Adenoma detection rate (ADR), the proportion of an endoscopist’s screening colonoscopies in which at least one adenoma is found, is an established quality metric. Several publications have suggested that a technique referred to as “one and done,” where less attention is paid to additional polyp detection following discovery of one likely adenoma, may be occurring 1 2 3. To investigate whether this practice occurs and provide additional context to the significance of ADR, we examined ADR by single and multiple adenomas in the statewide New Hampshire Colonoscopy Registry (NHCR). Patients and methods A total of 25,324 NHCR patients receiving screening colonoscopies between 2009 and 2014 by 69 endoscopists were analyzed. ADR was dichotomized into high (≥ 20 %) and low (< 20 %) based on 2006 recommended targets in place during the time of the study. ADR-plus (the average number of adenomas in colonoscopies with > 1 adenoma) was dichotomized at mean values into high (≥ 1.5) and low (< 1.5). As suggested by others, a high ADR but low ADR-plus was used to indicate the “one and done” approach. Results Among endoscopists with an ADR ≥ 20 %, only 5 (7.2 %) had low ADR-plus values and were classified as “one and done.” Results for serrated polyp detection were similar. ADR and ADR-plus decreased monotonically with increasing years since residency (P values for trend ADR = 0.02; ADR-plus = 0.003) after adjusting for patient risk factors. Conclusion “One and done” infrequently occurred among endoscopists with high ADR in a large statewide registry. The need to replace ADR with other polyp detection metrics (such as ADR-plus) to accurately ascertain performance quality is not supported by these findings.


2012 ◽  
Vol 107 ◽  
pp. S795
Author(s):  
Shashideep Singhal ◽  
Deepanshu Jain ◽  
Mojdeh Momeni ◽  
Sushil Duddempudi ◽  
Mahesh Krishnaiah ◽  
...  

Gut ◽  
2017 ◽  
Vol 67 (12) ◽  
pp. 2124-2130 ◽  
Author(s):  
Manuel Zorzi ◽  
Cesare Hassan ◽  
Giulia Capodaglio ◽  
Chiara Fedato ◽  
Adriana Montaguti ◽  
...  

BackgroundThe long-term performance of colorectal cancer (CRC) screening programmes based on a 2-year faecal immunochemical test (FIT) is still unclear.MethodsIn a sample of 50 to 69-year-olds repeatedly screened with the FIT (OC-Hemodia latex agglutination test; cut-off: 20 µg haemoglobin/g faeces), we examined: (1) the FIT positivity rate, the CRC and advanced adenoma detection rate and the FIT’s positive predictive value (PPV) for advanced neoplasia, at each round of screening and (2) the cumulative CRC and advanced adenoma detection rate after five rounds of FIT.ResultsOver 12 years (2002–2014), 123 347 individuals were administered the FIT up to six times, and 781 CRCs and 4713 advanced adenomas were diagnosed. The CRC and advanced adenoma detection rates declined substantially from the first to the third (rate ratio (RR) 0.25, 95% CI 0.20 to 0.32) and second (RR 0.51, 95% CI 0.47 to 0.56) rounds, respectively, and then remained stable. The PPV for advanced neoplasia dropped by 18% in the second round (RR 0.82, 95% CI 0.77 to 0.89), with no further reduction thereafter due to a concomitant decline in the FIT positivity rate (RR first to sixth rounds: 0.56, 95% CI 0.53 to 0.60).The cumulative CRC and advanced adenoma detection rates over five consecutive rounds were 8.5‰ (95% CI 7.8 to 9.2), and 58.9‰ (95% CI 56.9 to 61.0), respectively.ConclusionsRepeated FIT significantly reduces the burden of colorectal disease while facilitating an efficient use of colonoscopy resources. The cumulative detection rate after five rounds of FIT is similar to primary screening with colonoscopy, supporting the need to account for the cumulative sensitivity of repeated FITs when evaluating the test’s efficacy.


Sign in / Sign up

Export Citation Format

Share Document