scholarly journals Evidence that Climbing Fibers Control an Intrinsic Spike Generator in Cerebellar Purkinje Cells

2004 ◽  
Vol 24 (19) ◽  
pp. 4510-4517 ◽  
Author(s):  
N. L. Cerminara
2011 ◽  
Vol 71 ◽  
pp. e215
Author(s):  
Ryoichi Ichikawa ◽  
Miwako Yamasaki ◽  
Taisuke Miyazaki ◽  
Haruyuki Tatsumi ◽  
Masahiko Watanabe

2017 ◽  
Vol 143 (6) ◽  
pp. 660-670 ◽  
Author(s):  
Nobutaka Takahashi ◽  
Anton N. Shuvaev ◽  
Ayumu Konno ◽  
Yasunori Matsuzaki ◽  
Masashi Watanave ◽  
...  

Neuroscience ◽  
2010 ◽  
Vol 171 (3) ◽  
pp. 655-665 ◽  
Author(s):  
N.H. Barmack ◽  
Z. Qian ◽  
V. Yakhnitsa

2011 ◽  
Vol 31 (47) ◽  
pp. 16916-16927 ◽  
Author(s):  
R. Ichikawa ◽  
M. Yamasaki ◽  
T. Miyazaki ◽  
K. Konno ◽  
K. Hashimoto ◽  
...  

Author(s):  
R.V.W. Dimlich ◽  
M.H. Biros

In severe cerebral ischemia, Purkinje cells of the cerebellum are one of the cell types most vulnerable to anoxic damage. In the partial (forebrain) global ischemic (PGI) model of the rat, Paljärvi noted at the light microscopic level that cerebellar damage is inconsistant and when present, milder than in the telencephalon, diencephalon and rostral brain stem. Cerebellar injury was observed in 3 of 4 PGI rats following 5 minutes of reperfusion but in none of the rats after 90 min of reperfusion. To evaluate a time between these two extremes (5 and 90 min), the present investigation used the PGI model to study the effects of ischemia on the ultrastructure of cerebellar Purkinje cells in rats that were sacrificed after 30 min of reperfusion. This time also was chosen because lactic acid that is thought to contribute to ischemic cell changes in PGI is at a maximum after 30 min of reperfusion.


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