scholarly journals Analysis of self-associating proteins by singular value decomposition of solution scattering data

2008 ◽  
Vol 94 (12) ◽  
pp. 4906-4923 ◽  
Author(s):  
Tim E. Williamson ◽  
Bruce A. Craig ◽  
Elena Kondrashkina ◽  
Chris Bailey-Kellogg ◽  
Alan M. Friedman
2014 ◽  
Vol 369 (1647) ◽  
pp. 20130336 ◽  
Author(s):  
Kristoffer Haldrup

The development of new X-ray light sources, XFELs, with unprecedented time and brilliance characteristics has led to the availability of very large datasets with high time resolution and superior signal strength. The chaotic nature of the emission processes in such sources as well as entirely novel detector demands has also led to significant challenges in terms of data analysis. This paper describes a heuristic approach to datasets where spurious background contributions of a magnitude similar to (or larger) than the signal of interest prevents conventional analysis approaches. The method relies on singular-value decomposition of no-signal subsets of acquired datasets in combination with model inputs and appears generally applicable to time-resolved X-ray diffuse scattering experiments.


2017 ◽  
Author(s):  
Ammar Ismael Kadhim ◽  
Yu-N Cheah ◽  
Inaam Abbas Hieder ◽  
Rawaa Ahmed Ali

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