Glucocorticoid resistance patients exhibit defective cortisol metabolism, responsible for functional hypermineralocorticism

2019 ◽  
Author(s):  
Geraldine Vitellius ◽  
Brigitte Delemer ◽  
Olivier Chabre ◽  
Philippe Caron ◽  
Eric Pussard ◽  
...  
Keyword(s):  
Glucocorticoid Resistance ◽  
Cortisol Metabolism

Glucocorticoid resistance may be implicated in the emergence of ETV6/RUNX1- positive relapses

2011 ◽  
Vol 223 (03) ◽  
Author(s):  
R Grausenburger ◽  
L Kuster ◽  
A Inthal ◽  
R Panzer-Grümayer
Keyword(s):  
Glucocorticoid Resistance

VARIATION OF CORTISOL METABOLISM AS A CONTRIBUTING FACTOR TO DISCREPANCIES IN THE MEASUREMENT OF CORTISOL PRODUCTION RATE

1972 ◽  
Vol 70 (1) ◽  
pp. 89-96 ◽  
Author(s):  
M. J. Levell
Keyword(s):  
Production Rate ◽  
Isotope Dilution ◽  
Normal Subjects ◽  
Contributory Factor ◽  
Morning Dose ◽  
Production Rates ◽  
Evening Dose ◽  
Cortisol Metabolism

ABSTRACT Five normal subjects were given [14C] cortisol in the morning and [3H] cortisol in the evening, in both cases by mouth. The excretion of radioactivity in tetrahydrocortisol (THF) and tetrahydrocortisone (THE) was measured by a modified form of reverse isotope dilution. In 2 subjects, the ratio of isotopic THF/isotopic THE was higher after the evening dose than after the morning dose. In 1 subject the ratio decreased. In 2 subjects it did not change. Cortisol production rates calculated from THF were usually higher than those calculated from THE. The observed variations of metabolism were only a contributory factor to these discrepancies.

CORTISOL METABOLISM DURING HEMODIALYSIS

1975 ◽  
Vol 80 (1_Suppla) ◽  
pp. S145
Author(s):  
K. A. Deck ◽  
L. Eberlein ◽  
H. Hillen ◽  
B. Fischer
Keyword(s):  
Cortisol Metabolism
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