Is Preoperative Eosinopenia an Independent Predictor of Early Mortality for Coronary Artery Bypass Surgery?

2016 ◽  
Vol 19 (2) ◽  
pp. 088 ◽  
Author(s):  
Özge Korkmaz ◽  
Hakki Kaya ◽  
Osman Beton ◽  
Ali Zorlu ◽  
Sabahattin Göksel ◽  
...  

<strong>Objective:</strong> Coronary artery bypass graft surgery in one of the most effective and widely used methods employed in the treatment of ischemic heart disease, but many factors to various degrees are directly associated with perioperative and postoperative problems. In this study, we evaluated the relationship between preoperative eosinophil count and postoperative mortality in patients who underwent coronary artery bypass graft operation. <br /><strong>Methods:</strong> A total of 241 patients (157 males, 84 females) who underwent isolated on-pump coronary artery bypass graft operation between 2011 and 2013 in two centers were evaluated retrospectively. The mean age of patients was 64 ± 11 years. After the mean 6.2 ± 0.8 month follow-up period, <br />36 (15%) of the 241 patients experienced cardiovascular death. Patients were classified into two groups as those who survived versus those who died. <br /><strong>Results:</strong> Eosinophil levels were lower among the patients who died compared to the patients who survived (0.8 [0-3.8] versus 1.7 [0-9.4] ×1000 cells/mm3; P &lt; .001). Optimal cut-off level of eosinophils for predicting mortality was determined as ≤1.6 ×1000 cells/mm3, with a sensitivity of 85.7% and specificity of 51.0% (area under curve, 0.703; 95% CI, 0.641-0.760).<br /><strong>Conclusion:</strong> Eosinopenia was used as the predictor of mortality in pediatric and adult patients in the intensive care units. Eosinopenia after coronary artery bypass graft can be related to the endogenous stress hormones, and insufficiency of the existing cardiac status. Eosinophil levels can assist and facilitate risk stratification for patients with coronary artery bypass graft.

2021 ◽  
Author(s):  
Maasoumeh Barkhordari-Sharifabad ◽  
Fatemeh Zerang

Abstract Background Hemodynamic changes are among the common complications after coronary artery bypass graft (CABG) surgery. Incentive spirometry and deep breathing exercises are widely used in patients undergoing coronary artery bypass graft surgery. The aim of the present study was to compare the effect of incentive spirometry and deep breathing exercises on hemodynamic parameters of patients undergoing coronary artery bypass graft surgery. Methods This is a clinical trial that was performed on 40 heart patients who were candidates for coronary artery bypass graft surgery. Participants were selected using convenience sampling and then randomly divided into two groups. One day before surgery, one group was taught how to perform deep breathing exercises (DBE) and the other group was taught how to use incentive spirometry in practice. Hemodynamic indices were measured and recorded before the intervention, the first, second, and the third day after the intervention. Data analysis was carried out using SPSS ver.16 and descriptive and inferential statistical tests. Findings: The mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) on the first day after the intervention in patients undergoing the incentive spirometry group was significantly higher than the DBE group (p < 0.05). On the third day after the intervention, the mean arterial SaO2 in patients of the incentive spirometry group was significantly higher than the DBE group and the mean respiratory rate (RR) in patients in the incentive spirometry group was significantly lower than the DBE group (p < 0.05). However, there was no significant difference between the two groups in terms of other indices (p > 0.05). Conclusion The results showed that incentive spirometry has a greater effect on hemodynamic indices of patients undergoing CABG compared to DBE, so, it is recommended to use incentive spirometry to improve hemodynamic indices in these patients. Trial registration: Iranian Registry of Clinical Trials (IRCT), IRCT20191028045267N1. Registered 12 March 2020, https://www.irct.ir/trial/43365


Author(s):  
Mehdi Hadadzadeh ◽  
Mahdiesadat Mirahmadi ◽  
Masoud Mirzaei ◽  
Ali Pedarzadeh ◽  
Bahram Ghasemzadeh ◽  
...  

Background: Percutaneous coronary intervention (PCI) has become the first-choice treatment strategy the world over for patients with chronic coronary artery disorders. This study compared the effects of previous PCI procedures on the short-term postoperative results of coronary artery bypass graft surgery (CABG). Methodsː This cross-sectional analytical study recruited 220 patients who underwent CABG in Afshar Hospital in the Iranian city of Yazd between March 2009 and February 2013. The mean postoperative morbidity and mortality rates, the mean postoperative left ventricular ejection fraction (LVEF), the mean hemorrhage volume, the mean serum urea level, and the mean length of stay in the intensive care unit (ICU) were compared between the PCI and non-PCI groups. Results: Among the 220 participants, 147(66.8%) were male and 73(33.2%) were female. The mean age of the study population was 59.41±10.52 years. There was no significant difference in the risk of mortality between the 2 groups (P=0.369). The mean serum urea level was 21.14±6.52 mg/dL in the PCI group and 14.45±1.08 mg/dL in the non-PCI group (P=0.016). The mean postoperative LVEF was 43.19±8.81% in the PCI group and 45.51±8.15% in the non-PCI group (P=0.044). The mean length of stay in the ICU was 3.34±1.23 days in the PCI group and 2.22±0.56 days in the non-PCI group (P<0.001). The mean hemorrhage volume was 1113.01±428.13 mL in the PCI group and 961.42±228.31 mL in the non-PCI group (P=0.027). Conclusion: Previous PCI procedures did not affect the post-CABG mortality rate; however, some postoperative results were worse in the PCI group than in the non-PCI group, which should be considered before the selection of the revascularization method.   J Teh Univ Heart Ctr 2019;14(2):53-57   This paper should be cited as: Hadadzadeh M, Mirahmadi M, Mirzaei M, Pedarzadeh A, Ghasemzadeh B, Rahimianfar AA. Comparison of Short-term Results between Patients Undergoing Coronary Artery Bypass Graft with a Stent-Placement History and Patients Undergoing Primary Coronary Artery Surgery. J Teh Univ Heart Ctr 2019;14(2):53-57.


2006 ◽  
Vol 55 (5) ◽  
pp. 451
Author(s):  
Seung Ho Joo ◽  
Byoung Wook Choi ◽  
Jae Seung Seo ◽  
Young Jin Kim ◽  
Tae Hoon Kim ◽  
...  

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