Metagenomic Next-Generation Sequencing in the Diagnosis of Deep Sternal Wound Infection After Cardiac Transplantation: A Case Report and Literature Review
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Purpose: To explore the value of metagenomics next-generation sequencing (mNGS) for deep sternal wound infection (DSWI) diagnosis. Methods: mNGS was used to diagnose DSWI after cardiac transplantation; DSWI was treated with surgical debridement, wound care, and antibiotic therapy guided by mNGS. Results: Coinfection of methicillin-resistant Staphylococcus aureus (MRSA) and cytomegalovirus (CMV) was detected in this patient. The infection was controlled and the wound healed successfully with the specific medicine based on mNGS results for 3 weeks. Conclusion: mNGS is effective to achieve precise, individualized, and rapid treatment for wound infection.
2014 ◽
Vol 52
(7)
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pp. 2583-2594
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2019 ◽
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2019 ◽
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2010 ◽
Vol 58
(S 01)
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