In Vitro Toxicity Test of Ethyl 2-Cyanoacrylate, a Tissue Adhesive Used in Cardiovascular Surgery, by Fibroblast Cell Culture Method

2005 ◽  
Vol 8 (3) ◽  
pp. E169-E172 ◽  
Author(s):  
Mehmet Kaplan ◽  
Kemal Baysal
Keyword(s):  
Cell Culture ◽  
Toxicity Test ◽  
Cardiovascular Surgery ◽  
Culture Method ◽  
Fibroblast Cell ◽  
Tissue Adhesive ◽  
In Vitro Toxicity ◽  
Fibroblast Cell Culture ◽  
In Vitro Toxicity Test

In vitro toxicity test of 2-cyanoacrylate polymers by cell culture method

1990 ◽  
Vol 24 (10) ◽  
pp. 1355-1367 ◽  
Author(s):  
Yin-Chao Tseng ◽  
Yasuhiko Tabata ◽  
Suong-Hyu Hyon ◽  
Yoshito Ikada
Keyword(s):  
Cell Culture ◽  
Toxicity Test ◽  
Culture Method ◽  
In Vitro Toxicity ◽  
In Vitro Toxicity Test

Preparation, Characterization and in vitro Toxicity Test of Magnetic Nanoparticle-Based Drug Delivery System to Hyperthermia of Biological Tissues

2007 ◽  
Vol 43 (6) ◽  
pp. 2459-2461 ◽  
Author(s):  
Andreza Ribeiro Simioni ◽  
Fernando Lucas Primo ◽  
Marcilene Machado Andrade Rodrigues ◽  
Zulmira Guerrero Marques Lacava ◽  
Paulo Cesar Morais ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Toxicity Test ◽  
Magnetic Nanoparticle ◽  
Biological Tissues ◽  
In Vitro Toxicity ◽  
In Vitro Toxicity Test

scholarly journals In vitro toxicity test of poisonous mushroom extracts with isolated rat hepatocytes.

1990 ◽  
Vol 15 (3) ◽  
pp. 145-156 ◽  
Author(s):  
Akiko KAWAJI ◽  
Tomomichi SONE ◽  
Reiko NATSUKI ◽  
Masakazu ISOBE ◽  
Eigo TAKABATAKE ◽  
...  
Keyword(s):  
Toxicity Test ◽  
Rat Hepatocytes ◽  
In Vitro Toxicity ◽  
Isolated Rat Hepatocytes ◽  
Poisonous Mushroom ◽  
In Vitro Toxicity Test ◽  
Isolated Rat ◽  
Mushroom Extracts

Separation, isolation and stereochemical assignment of imazalil enantiomers and their quantitation in an in vitro toxicity test

2016 ◽  
Vol 1452 ◽  
pp. 116-120 ◽  
Author(s):  
Mònica Escolà Casas ◽  
Andreas Christopher Kretschmann ◽  
Lars Andernach ◽  
Till Opatz ◽  
Kai Bester
Keyword(s):  
Toxicity Test ◽  
In Vitro Toxicity ◽  
Stereochemical Assignment ◽  
In Vitro Toxicity Test

scholarly journals Testing in vitro toxicity of nanoparticles in 3D cell culture with various extracellular matrix scaffold

2021 ◽  
Author(s):  
Jae Won Choi ◽  
Song-Hwa Bae ◽  
In Young Kim ◽  
Minjeong Kwak ◽  
Tae Geol Lee ◽  
...  
Keyword(s):  
Cell Culture ◽  
3D Cell Culture ◽  
Cancer Cell Line ◽  
Culture Method ◽  
Sio2 Nanoparticles ◽  
Toxicity Assessment ◽  
In Vitro Toxicity ◽  
Dimensional Cell

Nanomaterials are used in a variety of fields and toxicity assessment is paramount for their development and application. Although most toxicity assessments have been performed in 2D (2-Dimensional) cell culture, the inability to adequately replicate the in vivo environment and toxicity is a limitation. To overcome the limitation, a 3D (3-Dimensional) cell culture method has been developed to make an environment closer to an in vivo system. In this study, 20 nm SiO2 nanoparticles were dispersed in serum-containing (SC) and serum-free (SF) media to compare 2D cell culture and 3D cell culture toxicity. The cells were subjected to a 3D cell culture method in which HepG2, a human-derived liver cancer cell line, was mixed on a scaffold. We found that nanoparticles induced toxicity in 2D cell culture, but toxicity was not observed in 3D cell culture similar to in vivo environment. However, differences in toxicity were observed between the three types of scaffolds in the absence of serum as the number of cells decreased.

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