Results of the Special Health Examination-Studies on the Seasonal Variation of Peripheral Circulation

Many studies have been conducted regarding the association between night work and diabetes, but the association between impaired fasting glucose (IFG) and night work is still unclear. The aim of this study was to evaluate this association using the Special Health Examination (SHEW) for Korean night workers. Laboratory, questionnaire, and physical examination data were collected for 80,077 manual workers between 2014 and 2016 from Korea Medical Institute, and associations of the data with IFG were evaluated using a multivariate logistic regression model. The odds ratios for IFG among those who worked night shifts for 2~5 years, 5~12 years, and 12 years or over (ref: <2 years) after adjusting for abdominal obesity were 1.14 (0.90–1.45), 1.41 (1.10–1.81), and 1.75 (1.41–2.19), respectively. A dose–response relationship was identified between the duration of night work and the prevalence of IFG (p for trend <0.05). A dose relationship remained significant when a subgroup of non-obese participants was analyzed. We identified an association and a dose–response relationship between the number of years of night work and IFG. To prevent the development of diabetes in night workers, we suggest that they should be pre-emptively screened and treated from the stage of IFG.

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Geographic, gender and seasonal variation of diabetes: a nationwide study among 1.4 million participants

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/clinem/dgab543 ◽

2021 ◽

Author(s):

Yuanfeng Zhang ◽

Mingkun Tong ◽

Bo Wang ◽

Zumin Shi ◽

Ping Wang ◽

...

Keyword(s):

Seasonal Variation ◽

Glycemic Control ◽

Census Data ◽

Fasting Blood Glucose ◽

Geographic Location ◽

Self Report ◽

Population Census ◽

Health Examination ◽

And Gender ◽

And Control

Abstract Background China experienced a rapid increase in the prevalence of diabetes. Objectives To assess the prevalence of diabetes among Chinese adults who attend preventive physical examination, and analyzed geographical and gender difference in seasonal variation of fasting blood glucose (FBG). Methods The study used data from 1,390,088 participants attending preventive health examination at 430 health screening centers in 220 cities. Diagnosis of diabetes and prediabetes were based on FBG and hemoglobinA1c and self-report physician’s diagnosis. We calculated age and sex standardized prevalence of diabetes according to the sixth Chinese population census data in 2010. Geographical distribution of diabetes and prediabetes were displayed on the country map. FBG were analyzed to detect the seasonal variation adjusted for age and gender by geographic location. Results The standardized prevalence of diabetes was 8.70% (95% CI, 8.22%-9.19%), 10.7% in men and 6.61% in women. Among those with diabetes, 43.7% (95% CI, 40.9%-46.5%) were aware of their conditions and 38.5% (95% CI, 36.0%-41.1%) were treated. Only 49.3% (95% CI, 47.0%-51.6%) of treated patients achieved glycemic control. The mean level of FBG was higher in winter than summer and in the northern than the southern. Conclusions The prevalence of diabetes was high whilst the percentages of awareness, treatment and glycemic control were low among adults. Effective measures are needed to prevent and manage diabetes in China. Geographic and seasonal variation of diabetes should be considered for its prevention and control.

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