Prolonged Apnea, Vagal Overactivity, and Sudden Infant Death

PEDIATRICS ◽  
1973 ◽  
Vol 51 (4) ◽  
pp. 755-755
Author(s):  
David S. Bachman
Keyword(s):  
At Risk ◽  
Vagus Nerve ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Vagal Stimulation ◽  
Sudden Infant Death ◽  
Sudden Infant ◽  
Prolonged Apnea ◽  
Stimulation Of

The article on prolonged apnea and the sudden infant death syndrome (SIDS) by Steinschneider1 is very exciting in that it suggests the possibility of identifying infants at risk from SIDS before the final event. Obviously, it is of great importance to learn the mechanism causing the preceding apneic episodes. Do they represent vagal overactivity? Stimulation of the intact vagus nerve in the unanesthetized monkey causes apnea, as well as bradycardia and even arrhythmias.2 In fact, we have seen myocardial myocytolysis secondary to vagal stimulation.3

Assessment of compliance with home cardiorespiratory monitoring in infants at risk of sudden infant death syndrome

1995 ◽  
Vol 127 (3) ◽  
pp. 384-388 ◽  
Author(s):  
Jean M. Silvestri ◽  
David R. Hufford ◽  
Jane Durham ◽  
Sheilah M. Pearsall ◽  
Mary Ann Oess ◽  
...  
Keyword(s):  
At Risk ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Sudden Infant Death ◽  
Sudden Infant ◽  
Assessment Of Compliance

SLEEP MONITORING IN INFANTS AT RISK FOR SUDDEN INFANT DEATH SYNDROME

1991 ◽  
Vol 36 (s1) ◽  
pp. 434-435 ◽  
Author(s):  
Gerhard Litscher ◽  
Gert Pfurtscheller ◽  
Karlheinz Matuschik ◽  
Dieter Gergen ◽  
Reinhard Haidmayer ◽  
...  
Keyword(s):  
At Risk ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Sudden Infant Death ◽  
Sudden Infant ◽  
Sleep Monitoring

scholarly journals ASSESSMENT OF SLEEP POSITION AMONG INFANTS AT RISK OF SUDDEN INFANT DEATH SYNDROME (SIDS). † 661

1996 ◽  
Vol 39 ◽  
pp. 113-113 ◽  
Author(s):  
Jean M Silvestri ◽  
Michael J Corwin ◽  
Larry Tinsley ◽  
Tom G Keens ◽  
Carl E Hunt ◽  
...  
Keyword(s):  
At Risk ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Sudden Infant Death ◽  
Sleep Position ◽  
Sudden Infant

Close encounters with SIDS

PEDIATRICS ◽  
1978 ◽  
Vol 61 (4) ◽  
pp. 664-665
Author(s):  
Ann R. Stark ◽  
Frederick Mandell ◽  
H. William Taeusch
Keyword(s):  
At Risk ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Age Distribution ◽  
Sudden Infant Death ◽  
Sudden Infant ◽  
Live Births ◽  
Close Encounters ◽  
At Home

The use of apnea monitors at home to prevent sudden infant death syndrome (SIDS) in infants at risk is a debated issue. Several very difficult questions await answers: (1) Who should be monitored? (2) What kinds of monitors would be most effective? (3) Does monitoring work? (4) Are other approaches apt to be simpler and more efficacious, e.g., respiratory stimulants? What is known about SIDS is mostly epidemiologic information. The incidence is 2 to 3 per 1,000 live births, with a peak age distribution between 2 and 4 months. Most deaths are silent and occur when the infant is supposedly asleep.

PROLONGED APNEA AND THE SUDDEN INFANT DEATH SYNDROME: CLINICAL AND LABORATORY OBSERVATIONS

PEDIATRICS ◽  
1994 ◽  
Vol 93 (6) ◽  
pp. 944-944
Author(s):  
Alfred Steinschneider
Keyword(s):  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Critical Role ◽  
Warning System ◽  
Sudden Infant Death ◽  
Serial Killer ◽  
Medical Examiner ◽  
Sudden Infant ◽  
Pediatric Pathology ◽  
Prolonged Apnea

A 25-Year Trail to Murder Charges—... The first suspicions were raised in 1985 by Dr. Linda Norton, a former medical examiner for Dallas County, Texas, and an expert on pediatric pathology, who had been a consultant in the VanDerSluys case. "You may have a serial killer in Syracuse," she told the prosecutor in giving him a copy of an October 1972 article in Pediatrics (1972;50(4)) called "Prolonged Apnea and the Sudden Infant Death Syndrome: Clinical and Laboratory Observations." In the report Dr. Steinschneider described his work with the syndrome and how two children in a family plagued with the affliction had died within hours of their release from his Syracuse research project. In his paper, Dr. Steinschneider concluded that the family, which he still identifies only as "H," showed that victims suffered from real if almost undetectable physical abnormalities. In a proposal that was radical then but is now accepted, he suggested that the syndrome had a genetic component and was therefore inherited. He suggested that scientists could identify the abnormalities and thereby devise a warning system. "But the paper indicated a more sinister possibility to Dr. John F. Hick of Minnesota. In a letter to the journal, he wrote that the case offered "circumstantial evidence suggesting a critical role for the mother in the death of her children." (See below.) But his warning was dismissed, until Mr. Fitzpatrick read the paper 15 years later. "The medical records described two happy, healthy, perfectly normal kids," he said. "It convinced me that these children were murdered."

Sudden Infant Death Syndrome and Child Abuse

PEDIATRICS ◽  
1973 ◽  
Vol 52 (1) ◽  
pp. 147-147
Author(s):  
John F. Hick
Keyword(s):  
Child Abuse ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Sudden Infant Death ◽  
The Other ◽  
Sudden Infant ◽  
Common Denominator ◽  
Prolonged Apnea ◽  
The Common ◽  
Family Chronicle

In reporting two siblings who succumbed to "sudden infant death syndrome," Steinschneider exposes an unparalleled family chronicle of infant death.1 Of five children, four died in early infancy and the other died without explanation at age 28 months. Prolonged apnea is proposed as the common denominator in the deaths, yet the author leaves many questions relevant to the fate of these children unanswered. Apnea of greater than 15 seconds has been well documented for the two siblings studied.

Sudden Infant Death Syndrome and Child Abuse

PEDIATRICS ◽  
1994 ◽  
Vol 93 (6) ◽  
pp. 944-944
Author(s):  
J. F. Hick
Keyword(s):  
Child Abuse ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Sudden Infant Death ◽  
The Other ◽  
Sudden Infant ◽  
Common Denominator ◽  
Prolonged Apnea ◽  
The Common ◽  
Family Chronicle

In reporting two siblings who succumbed to "sudden infant death syndrome," Steinschneider exposes an unparalleled family chronicle of infant death.1 Of five children, four died in early infancy and the other died without explanation at age 28 months. Prolonged apnea is proposed as the common denominator in the deaths, yet the author leaves many questions relevant to the fate of these children unanswered.

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