A recurrence case of keratocystic odontogenic tumor

2017 ◽  
Vol 4 (1) ◽  
pp. 1-4
Author(s):  
Tejavathi Nagaraj ◽  
Haritma Nigam ◽  
Arundhati Biswas ◽  
C. K. Sumana
2007 ◽  
Vol 49 (3) ◽  
pp. 229-235 ◽  
Author(s):  
Ataollah Habibi ◽  
Nasrollah Saghravanian ◽  
Mehdi Habibi ◽  
Ehsan Mellati ◽  
Morteza Habibi

2011 ◽  
Vol 22 (6) ◽  
pp. 2347-2350 ◽  
Author(s):  
Francesco Arcuri ◽  
Fabrizio Grivetto ◽  
Giuseppe Poglio ◽  
Matteo Brucoli ◽  
Arnaldo Benech

2021 ◽  
Vol 12 (1) ◽  
pp. 134-143
Author(s):  
Merlin Jayaraj ◽  
Pratibha Ramani ◽  
Herald J. Sherlin

Background: Keratocystic odontogenic tumor (KCOT) is an odontogenic lesion which manifests distinct biological behavior. Predominant studies in KCOT attribute this behavior to high epithelial proliferative capacity. Besides, a few studies facet loosely arranged collagen can contribute to the behavior of KCOT. Matrix metalloproteinases (MMP) are enzymes that degrade extracellular matrix components under both physiologic and pathologic conditions. The loosely arranged collagen in connective tissue wall of KCOT could be related to the degree of MMP-9 expression. Aim: To evaluate the arrangement of collagen fibers along with immunoexpression of MMP-9 and to relate to its neoplastic biologic behavior in sporadic cases of KCOT. Materials and Methods: KCOT ( n = 23) and dentigerous cyst (DC) ( n = 15) samples were processed for the following techniques: Masson’s trichrome stain for light microscopy, PMA-PSR stain for confocal microscopy, and MMP-9 for immunohistochemistry. Results: In Masson’s trichrome analysis, correlation of collagen fiber arrangement in the deeper regions with color intensity for KCOT was found to be statistically significant ( P = .033). In confocal microscopy, there was no difference between intensities in KCOT ( P = .990) and DC ( P = .233), respectively. The immunoexpression of MMP-9 in the connective tissue wall of DC (73.3%) was relatively higher than that of KCOT (60.8%). However, on comparison between KCOT and DC in the presence of inflammation, the immunoexpression of MMP-9 was higher in DC (100%) than KCOT (69.9%) and was statistically significant ( P = .028). Conclusion: It was concluded that the loose connective tissue wall in KCOT is because of the inherent nature of the lesion that could facilitate its biologic behavior. If inflammation is present, this could further aggravate the tumorigenic behavior.


2016 ◽  
Vol 43 (6) ◽  
pp. 466-471 ◽  
Author(s):  
BRENDA DE SOUZA MOURA ◽  
MARIA APARECIDA CAVALCANTE ◽  
WAGNER HESPANHOL

ABSTRACT Objective: to evaluate the frequency of keratocystic odontogenic tumor (KOT) in the Oral Surgery Service (OSS) of the University Hospital Clementino Fraga Filho of the Federal University of Rio de Janeiro (HUCFF / UFRJ), with respect to recurrence rate, gender, age of recurrence and location of the injury Methods: clinical records were reviewed and histopathological reports of KOT patients of the HUCFF/UFRJ between 2002 and 2012. Patients diagnosed with KOT were divided into two groups for the occurrence of relapse: positive (n=6) and negative (n=19) Results: regarding the location, there was a predilection for the mandible. In the average age of patients in the positive group was 40.5 and the negative group, 35.53. In the distribution by gender, positive group showed equal distribution, different from that observed in the negative group, which showed a predilection for males Conclusion: KOT was the second most frequent injury in our patients, recurrence was lower among males and had the jaw as most affected location


2015 ◽  
Vol 9 (2) ◽  
pp. 219-226 ◽  
Author(s):  
Caroline Brandi Schlaepfer-Sales ◽  
Ludmila De Faro Valverde ◽  
Rosane Borges Dias ◽  
Bruna Natália Alves Da Silva Pimentel ◽  
Leonardo De Araújo Melo ◽  
...  

2016 ◽  
Vol 6 (3) ◽  
pp. 41-46 ◽  
Author(s):  
Rachna Kaushik ◽  
Kumar Pushpanshu ◽  
Silky Rajesh Punyani ◽  
Vineet Raj

Author(s):  
Camilla Siqueira De Aguiar ◽  
Natália Zanin Perelmuter De Melo ◽  
Marcela Cortê Real Fernandes ◽  
Milena Mello Varela Ayres De Melo Pinheiro ◽  
Victor Leonardo Mello Varela Ayres De Melo ◽  
...  

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