scholarly journals Diagnosis and management of systemic hypertension due to renovascular and aortic stenosis in patients with Williams-Beuren syndrome

2018 ◽  
Vol 64 (8) ◽  
pp. 723-728
Author(s):  
Erika Arai Furusawa ◽  
Camila Sanches Lanetzki Esposito ◽  
Rachel Sayuri Honjo ◽  
Lisa Suzuki ◽  
Gabriela Nunes Leal ◽  
...  

SUMMARY AIM To describe the incidence, diagnosis, and management of systemic arterial hypertension related to renal artery stenosis in patients with Williams-Beuren syndrome. METHODS Sixty-five patients with Williams-Beuren syndrome were evaluated for hypertension. Enrolled patients underwent Doppler sonography of the renal arteries and Doppler echocardiography. Those with Doppler sonography-detected lesions or with normal Doppler sonography but severe hypertension underwent computed tomography or gadolinium-enhanced magnetic resonance angiography of the aorta and renal vessels. Patients needing vascular therapeutic intervention underwent conventional angiography. RESULTS Systemic arterial hypertension was diagnosed in 21/65 patients with Williams-Beuren syndrome (32%; 13 male) with a mean age of 13.9 years (5mo-20yrs). In 8/21 patients renovascular hypertension was detected. Angioplasty was unsuccessful in five patients with renal artery stenosis, requiring additional treatment. Doppler echocardiography showed cardiac abnormalities in 16/21 (76%) hypertensive patients. CONCLUSION Cardiac abnormalities and hypertension in patients with Williams-Beuren syndrome are common. Thus, thorough evaluation and follow-up are necessary to reduce cardiovascular risks and mortality of these patients

2021 ◽  
Vol 05 (03) ◽  
Author(s):  
Isadora Langoni Amorim Barbosa ◽  
Tayenne do Vale Cabral ◽  
Mariana Carraro ◽  
Mariana Castro Loureiro Borges e Curi

2002 ◽  
Vol 32 (5) ◽  
pp. 384-386 ◽  
Author(s):  
Marjorie W. Stein ◽  
Mordecai Koenigsberg ◽  
Jerry Grigoropoulos ◽  
Bruce C. Cohen ◽  
Henry Issenberg

1992 ◽  
Vol 22 (7) ◽  
pp. 527-528 ◽  
Author(s):  
T. Rupprecht ◽  
D. Wenzel ◽  
E. Schmitzer ◽  
M. Hofbeck ◽  
B. Böwing ◽  
...  

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