scholarly journals Galveston Orientation and Amnesia Test: applicability and relation with the Glasgow Coma Scale

2007 ◽  
Vol 15 (4) ◽  
pp. 651-657 ◽  
Author(s):  
Silvia Cristina Fürbringer e Silva ◽  
Regina Marcia Cardoso de Sousa

Restrictions in the application of the Galveston Orientation and Amnesia Test and questionings about the relationship between conscience and post-traumatic amnesia motivated this study, which aims to identify, through the Glasgow Coma Scale scores, when to initiate the application of this amnesia test, as well to verify the relationship between the results of these two indicators. The longitudinal prospective study was carried at a referral center for trauma care in São Paulo - Brazil. The sample consisted of 73 victims of blunt traumatic brain injury, admitted at this institution between January 03rd and May 03rd 2001. Regarding the applicability, the test could be applied in patients with a Glasgow Coma Scale score > 12; however, the end of post traumatic amnesia was verified in patients who scored > 14 on the scale. A significant relationship (r s = 0.65) was verified between these measures, although different kinds of relationship between the end of the amnesia and changes in consciousness were observed.

2010 ◽  
Vol 27 (9) ◽  
pp. 1549-1555 ◽  
Author(s):  
Alexandra Brazinova ◽  
Walter Mauritz ◽  
Johannes Leitgeb ◽  
Ingrid Wilbacher ◽  
Marek Majdan ◽  
...  

Brain Injury ◽  
2015 ◽  
Vol 29 (5) ◽  
pp. 612-617 ◽  
Author(s):  
Daniel Simon ◽  
Josi Mara Botome Nicol ◽  
Sabrina Sabino da Silva ◽  
Camila Graziottin ◽  
Patrícia Corso Silveira ◽  
...  

2011 ◽  
Vol 71 (5) ◽  
pp. 1172-1178 ◽  
Author(s):  
Shelly D. Timmons ◽  
Tiffany Bee ◽  
Sharon Webb ◽  
Ramon R. Diaz-Arrastia ◽  
Dale Hesdorffer

Brain Injury ◽  
2010 ◽  
Vol 24 (7-8) ◽  
pp. 919-927 ◽  
Author(s):  
Rael T. Lange ◽  
Grant L. Iverson ◽  
Jeffrey R. Brubacher ◽  
Michael D. Franzen

2021 ◽  
Vol 11 (8) ◽  
pp. 1044
Author(s):  
Cristina Daia ◽  
Cristian Scheau ◽  
Aura Spinu ◽  
Ioana Andone ◽  
Cristina Popescu ◽  
...  

Background: We aimed to assess the effects of modulated neuroprotection with intermittent administration in patients with unresponsive wakefulness syndrome (UWS) after severe traumatic brain injury (TBI). Methods: Retrospective analysis of 60 patients divided into two groups, with and without neuroprotective treatment with Actovegin, Cerebrolysin, pyritinol, L-phosphothreonine, L-glutamine, hydroxocobalamin, alpha-lipoic acid, carotene, DL-α-tocopherol, ascorbic acid, thiamine, pyridoxine, cyanocobalamin, Q 10 coenzyme, and L-carnitine alongside standard treatment. Main outcome measures: Glasgow Coma Scale (GCS) after TBI, Extended Glasgow Coma Scale (GOS E), Disability Rankin Scale (DRS), Functional Independence Measurement (FIM), and Montreal Cognitive Assessment (MOCA), all assessed at 1, 3, 6, 12, and 24 months after TBI. Results: Patients receiving neuroprotective treatment recovered more rapidly from UWS than controls (p = 0.007) passing through a state of minimal consciousness and gradually progressing until the final evaluation (p = 0.000), towards a high cognitive level MOCA = 22 ± 6 points, upper moderate disability GOS-E = 6 ± 1, DRS = 6 ± 4, and an assisted gait, FIM =101 ± 25. The improvement in cognitive and physical functioning was strongly correlated with lower UWS duration (−0.8532) and higher GCS score (0.9803). Conclusion: Modulated long-term neuroprotection may be the therapeutic key for patients to overcome UWS after severe TBI.


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