Role of Hypertonic Saline for the Management of Intracranial Hypertension After Stroke and Traumatic Brain Injury

2008 ◽  
Vol 28 (4) ◽  
pp. 469-484 ◽  
Author(s):  
Lisa L Forsyth ◽  
Xi Liu-DeRyke ◽  
Dennis Parker ◽  
Denise H Rhoney
2017 ◽  
Vol 43 (5) ◽  
pp. E7 ◽  
Author(s):  
Areej Tariq ◽  
Pedro Aguilar-Salinas ◽  
Ricardo A. Hanel ◽  
Neeraj Naval ◽  
Mohamad Chmayssani

Intracranial pressure (ICP) monitoring has been widely accepted in the management of traumatic brain injury. However, its use in other pathologies that affect ICP has not been advocated as strongly, especially in CNS infections. Despite the most aggressive and novel antimicrobial therapies for meningitis, the mortality rate associated with this disease is far from satisfactory. Although intracranial hypertension and subsequent death have long been known to complicate meningitis, no specific guidelines targeting ICP monitoring are available. A review of the literature was performed to understand the pathophysiology of elevated ICP in meningitis, diagnostic challenges, and clinical outcomes in the use of ICP monitoring.


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